A5039990242- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Diet, Metabolism, and Disease
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Substance Abuse Treatment and Outcomes
- Tendon Structure and Treatment
- Healthcare Policy and Management
- Hematological disorders and diagnostics
- Hepatitis C virus research
- Organ Donation and Transplantation
- Elbow and Forearm Trauma Treatment
- Healthcare Systems and Reforms
- Viral gastroenteritis research and epidemiology
- Migration, Health and Trauma
- Global Health Care Issues
- Drug-Induced Hepatotoxicity and Protection
- Hepatocellular Carcinoma Treatment and Prognosis
- Infectious Encephalopathies and Encephalitis
- Aerospace and Aviation Technology
- Streptococcal Infections and Treatments
- COVID-19 and Mental Health
- Infective Endocarditis Diagnosis and Management
University of Southern California
2020-2025
Keck Hospital of USC
2022
University of California, San Francisco
2017-2021
Mount Elizabeth Hospital
2005-2021
UCSF Benioff Children's Hospital
2014-2018
Boeing (Australia)
2018
Johns Hopkins University
2016
Johns Hopkins Medicine
2016
Mayo Clinic
1995-1997
<h3>Importance</h3> Alcohol-associated liver disease (ALD) has emerged as the most common indication for transplant in United States, but data on reasons this increase and long-term post-liver outcomes among recipients are sparse. <h3>Objective</h3> To characterize trends of ALD States between 2002 2016. <h3>Design, Setting, Participants</h3> This multicenter, prospective, national cohort study used from Network Organ Sharing database to evaluate all transplants performed January 1, 2002,...
Objective: To examine our pilot to transplant selected patients with acute alcoholic hepatitis, initiated in October 2012. Background: Six months of alcohol abstinence is typically required before liver transplant. A Franco-Belgian protocol showed that early severe hepatitis could improve survival low incidence relapse. Application this controversial indication growing despite unclear generalizability. Methods: Data was collected on all alcohol-related disease since initiation the through...
Background and Aims: The multisociety consensus nomenclature has renamed NAFLD to steatotic liver disease (SLD) with various subclassifications. There is a paucity of data regarding how the new modifies our understanding prevalence patient phenotypes. Approach Results: Using National Health Nutrition Examination Survey from January 2017 March 2020, we included all participants aged 18 years or above complete vibration-controlled transient elastography measures. SLD its subclassifications...
Early liver transplant (LT) for alcohol-associated disease (i.e., without a specific sobriety period) is controversial but increasingly used. Using the multicenter American Consortium of Liver Transplantation Alcoholic Hepatitis (ACCELERATE-AH) cohort, we aimed to develop predictive tool identify patients pretransplant with low risk sustained alcohol use posttransplant inform selection candidates early LT. We included consecutive ACCELERATE-AH LT recipients between 2012 and 2017. All had...
Summary Backgrounds and Aims Alcohol use leads to disabilities deaths worldwide. It not only harms the liver but also causes alcohol disorder (AUD) heart disease. Additionally, consumption contributes health disparities among different socio‐economic groups. Methods We estimated global regional trends in burden of AUD, disease, cardiovascular disease from using methodology Global Burden Disease study. Results In 2019, highest disability‐adjusted life years rate per 100,000 population was due...
Background: Articular wear is considered to be a possible long-term complication of the use stemmed, coupled elbow replacements with capacity correct deformity and restore function. There have been no reports on this topic, our knowledge. Methods: A review results 919 semiconstrained linked Coonrad-Morrey total implant, performed between 1981 2000, revealed that twelve patients (1.3%) had undergone an isolated exchange articular bushings as result polyethylene wear. The status these was...
Background: The optimal choice for intervention recalcitrant lateral elbow tendinopathy remains unclear as various treatment modalities have documented comparable results in the literature. Purpose: To explore safety, tolerability, and early efficacy of a new minimally invasive mode that delivers focused, calibrated ultrasonic energy, effectively microresecting pathological tendon removing only tissue. Study Design: Case series; Level evidence, 4. Methods: Seven male 13 female patients aged...
Background: A previously published study found positive outcomes for a novel technique ultrasound-guided percutaneous ultrasonic tenotomy, showing good tolerability, safety, and early efficacy within an office setting. Purpose: In this follow-up study, all 20 members of the original cohort were contacted after 3 years to explore sustainability symptomatic relief, functional improvement, sonographic soft tissue response tenotomy. Study Design: Case series; Level evidence, 4. Methods: All...
The burden of chronic kidney disease (CKD) is rising among patients with cirrhosis, though it not known what impact this has had on outcomes after liver transplantation (LT). All listed for LT in the United States between 2002 and 2017 were analyzed, excluding those Model End-Stage Liver Disease (MELD) exceptions. primary outcome was post-LT mortality. We defined pre-LT CKD as an estimated glomerular filtration rate <60 mL/minute 90 days or ≥42 hemodialysis. Cox regression determined...
Abstract Background & Aims Bariatric surgery is common, but alcohol misuse has been reported following these procedures. We aimed to determine if bariatric associated with increased risk of alcohol‐related cirrhosis (AC) and misuse. Methods Retrospective observational analysis obese adults employer‐sponsored insurance administrative claims from 2008 2016. Subjects diagnosis codes for were included. Primary outcome was AC. Secondary divided into before after account patients who had a...
Early liver transplantation (LT) for alcohol-associated hepatitis (AH) is the fastest growing indication LT, but prediction of harmful alcohol use post-LT remains limited. Among 10 ACCELERATE-AH centers, we examined psychosocial evaluations from consecutive LT recipients AH 2006 to 2017. A multidisciplinary panel used content analysis develop a maximal list variables. We developed an artificial intelligence model predict use. The cohort included training (N = 91 among 8 centers) and external...
There is an ongoing outbreak of Mycobacterium chimaera infections among patients exposed to contaminated heater-cooler devices used during cardiac surgery. Recognition M. infection hampered by its long latency and non-specific symptoms. Standard diagnostic methods using acid-fast bacilli (AFB) culture often require invasive sampling, have low sensitivity, can take weeks result. We describe the performance a plasma-based next-generation sequencing test (plasma NGS) for diagnosis infection.We...
Alcohol‐associated liver disease (ALD) can be coded in United Network for Organ Sharing (UNOS) as either alcoholic cirrhosis or hepatitis (AH), without having specific criteria to assign diagnosis. In this multicenter American Consortium of Early Liver Transplantation Alcoholic Hepatitis (ACCELERATE‐AH) study, we sought assess the concordance clinician diagnosis AH at transplantation (LT) listing versus UNOS data entry a prior consecutive early LT recipients transplanted between 2012 and...