Huayou Chen

ORCID: 0000-0002-1010-8205
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About
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Research Areas
  • Enzyme Production and Characterization
  • Enzyme Catalysis and Immobilization
  • Enzyme-mediated dye degradation
  • Protein Hydrolysis and Bioactive Peptides
  • Enzyme Structure and Function
  • Protein Structure and Dynamics
  • Probiotics and Fermented Foods
  • Microbial Metabolic Engineering and Bioproduction
  • Algal biology and biofuel production
  • Peptidase Inhibition and Analysis
  • Lignin and Wood Chemistry
  • Biochemical and biochemical processes
  • Biofuel production and bioconversion
  • Heat shock proteins research
  • Phytase and its Applications
  • Microbial Metabolism and Applications
  • Bacteriophages and microbial interactions
  • Electrochemical sensors and biosensors
  • Animal Nutrition and Physiology
  • Protein purification and stability
  • Biochemical and Structural Characterization
  • Meat and Animal Product Quality
  • Advanced Nanomaterials in Catalysis
  • Studies on Chitinases and Chitosanases
  • Lipid metabolism and disorders

Jiangsu University
2015-2025

Hainan Medical University
2025

Anhui University
2024

Institute of Process Engineering
2015-2023

Second Affiliated Hospital of Xi'an Jiaotong University
2019-2022

Jingchu University of Technology
2021

Xi'an Jiaotong University
2019

Institute of Life Sciences
2015-2017

University of California, San Diego
2014-2016

Chinese Academy of Sciences
2006-2014

Traditional medicines are becoming more popular as people become aware of the dangers synthetic pharmaceuticals. Tribulus terrestris L., (Gokharu) an annual herbaceous plant, has been extensively utilized by herbalists for numerous medicinal purposes. T. studied its multiple therapeutic effects, including immunomodulatory, aphrodisiac, anti-urolithic, absorption enhancer, cardioprotective, antidiabetic, anti-inflammatory, hypolipidemic, neuro-protective, anticancer, and analgesic properties....

10.1016/j.heliyon.2024.e25549 article EN cc-by-nc-nd Heliyon 2024-01-30

The tons of keratin waste are produced by the poultry and meat industry which is an insoluble protein-rich material found in hair, feathers, wool, some epidermal wastes. These products could be degraded recycled to recover protein, can save our environment. One potential strategy achieve this target use microbial biotreatment more convenient, cost-effective, environment-friendly formulating hydrolysate complexes that administered as protein supplements, bioactive peptides, or animal feed...

10.1016/j.psj.2024.103606 article EN cc-by-nc-nd Poultry Science 2024-03-05

Essential oils (EOs), ascorbic acid, sugars, carotenoids, flavonoids, dietary fiber, polyphenols, and trace minerals are found in citrus residue. It gives animals energy promotes health. On a dry matter basis, the pulp is composed of 7% crude protein, 14% 21.6% nitrogen detergent 2.5% fat, 24.4% total 12.1% ME MJ/kg. has been reported that natural antioxidant content beneficial effect on growth microbial immunological parameters. The literature indicates ultimate weight gain poultry...

10.1016/j.psj.2024.103549 article EN cc-by-nc-nd Poultry Science 2024-02-13

Keratinases is a special hydrolytic enzyme produced by microorganisms, which has the ability to catalyze degradation of keratin. Currently, keratinases show great potential for application in many agricultural and industrial fields, such as biofermented feed, leather tanning, hair removal, fertilizer production. However, these potentials have not yet been fully unleashed on an scale. This paper reviews sources, properties, catalytic mechanisms keratinases. Strategies molecular modification...

10.1021/acs.jafc.4c03025 article EN Journal of Agricultural and Food Chemistry 2024-06-04

Rapeseed meal (RSM), a protein-rich byproduct, holds potential as high-quality animal feed, but nitrile compounds derived from glucosinolates (GSLs) in RSM pose toxicity risk. Nitrilases, enzymes that hydrolyze toxic nitriles to carboxylic acids, offer solution for detoxification. However, the low thermal stability of nitrilases restricts their industrial applicability. We herein identified eight ancestral through sequence-based mining using 6803NIT probe enzyme. Among these, enzyme A1...

10.1021/acs.jafc.4c09532 article EN Journal of Agricultural and Food Chemistry 2025-01-01

This study was conducted to obtain the optimal fermentation process improve nutritional value of bean dregs (BD) and soybean meal (SBM) using single-factor experiments response surface methodology with small peptide content as index. The follows: Bacillus subtilis selected for aerobic 12 h, Saccharomyces cerevisiae + Lactobacillus plantarum rhamnosus anaerobic fermentation, ratio BD SBM = 1:1, 0.65% acid protease +0.65% papain, 15% wheat middlings, 5% inoculum size, 34 °C temperature, 11 d...

10.1016/j.lwt.2021.112626 article EN cc-by-nc-nd LWT 2021-10-18

Some feed source plants will produce secondary metabolites such as cyanogenic glycosides during metabolism, which some poisonous nitrile compounds after hydrolysis and remain in plant tissues. The consumption of feed-source without proper treatment affect the health animals' bodies. Nitrilases can convert nitriles have been used industry green biocatalysts. However, due to their bottleneck problems, application agriculture is still facing challenges. Acid-resistant nitrilase preparations,...

10.1021/acs.jafc.4c03388 article EN Journal of Agricultural and Food Chemistry 2024-07-01

Chitin is the second most prevalent polysaccharide found in nature, following cellulose. Amino-oligosaccharides, byproducts of chitin degradation, exhibit favorable biological properties and potential for various uses. Chitinases play a crucial function breakdown chitin, their exceptionally effective production has garnered significant interest. Here, this study, exochitinase PbChiA, obtained from

10.3390/molecules29184302 article EN cc-by Molecules 2024-09-11

Addressing the demand for efficient biological degradation of straw, this study employed rational design coupled with structural biology and enzyme engineering techniques to enhance catalytic activity cellobiose dehydrogenase (

10.1021/acs.jafc.4c05991 article EN Journal of Agricultural and Food Chemistry 2024-10-28

To date, only two drugs, pirfenidone and nintedanib, are approved for the treatment of patients with idiopathic pulmonary fibrosis (IPF). In addition, very few studies have reported on safety profile either drug in large populations. This study aims to identify compare adverse events (ADEs) associated nintedanib real-world settings by analyzing data from US Food Drug Administration Adverse Event Reporting System (FAERS). we utilized Japanese Report (JADER) database external validation. The...

10.3389/fphar.2025.1530697 article EN cc-by Frontiers in Pharmacology 2025-04-28

Abstract BACKGROUND With the development of global poultry industry, millions tons feathers are produced each year. A significant proportion is improperly discarded, leading to a substantial loss keratin resources from feathers. Utilizing in feed industry could reduce costs substantially. However, new fermented lacks acid‐resistant keratinase, making it unable convert feather effectively lactic acid bacteria fermentation environment. RESULTS This study established high‐throughput screening...

10.1002/jsfa.14361 article EN Journal of the Science of Food and Agriculture 2025-05-13
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