- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Zeolite Catalysis and Synthesis
- Neuroinflammation and Neurodegeneration Mechanisms
- Traditional Chinese Medicine Analysis
- Catalytic Processes in Materials Science
- Allergic Rhinitis and Sensitization
- Neurological Disease Mechanisms and Treatments
- Catalysis and Hydrodesulfurization Studies
- Mesoporous Materials and Catalysis
- Natural Antidiabetic Agents Studies
- Food Quality and Safety Studies
- Adipose Tissue and Metabolism
- Asthma and respiratory diseases
- Catalysis and Oxidation Reactions
- Mast cells and histamine
- Phytochemistry and Biological Activities
- Chemical Synthesis and Characterization
- Ginseng Biological Effects and Applications
- Ginger and Zingiberaceae research
- Natural Compounds in Disease Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Petroleum Processing and Analysis
- Dermatology and Skin Diseases
Dongguk University
2015-2024
Shanxi University
2024
Korea Research Institute of Chemical Technology
2012-2023
Korea University of Science and Technology
2017-2023
Dunsan Korean Medicine Hospital
2015
Dongguk University WISE
2007-2014
Korea Institute of Oriental Medicine
2009-2013
Dankook University
2013
BongSeng Memorial Hospital
2010
Cornell University
2007
Abstract Amine-containing adsorbents have been extensively investigated for post-combustion carbon dioxide capture due to their ability chemisorb low-concentration from a wet flue gas. However, earlier studies focused primarily on the uptake of adsorbents, and not demonstrated effective adsorbent regeneration long-term stability under such conditions. Here, we report versatile scalable synthesis functionalized-polyethyleneimine (PEI)/silica which simultaneously exhibits large working...
Excessive production of nitric oxide (NO) and proinflammatory cytokines from activated microglia play an important role in human neurodegenerative disorders. Here, we investigated whether celastrol, which has been used as a potent anti-inflammatory anti-oxidative agent Chinese medicine, attenuates excessive NO such TNF-α IL-1β LPS-stimulated BV-2 cells, mouse microglial cell line. We report here that the LPS-elicited NO, TNF-α, cells was largely inhibited presence attenuation inducible iNOS...
Radix Pueraria lobata (RP) has been reported to prevent obesity and improve glucose metabolism; however, the mechanism responsible for these effects not elucidated. The underlying anti-obesity effect of RP was investigated in high-fat diet (HFD) induced obese mice skeletal muscle cells (C2C12). Five-week-old C5BL/6 were fed a HFD containing or (100 300 mg/kg) metformin (250 16 weeks. reduced body weight gain, lipid accumulation liver, adipocyte blood levels. In addition, dose-dependently...
The present study aimed to investigate the effects of monotropein (MON) on improving dexamethasone (DEX)-induced muscle atrophy in mice and C2C12 mouse skeletal cells. body weights, grip strengths, weights were assessed. histological change gastrocnemius tissues was also observed through H&E staining. expression myosin heavy chain (MyHC), ring finger 1 (MuRF1), F-box (Atrogin1) phosphorylation AKT, mTOR, FOXO3a myotubes analyzed using Western blotting. MON improved by regulating catabolic...
MOK, a pharmacopuncture medicine consisting of 10 herbs, has long history as treatment for various inflammatory conditions. To investigate the mechanisms action its anti‑inflammatory and antioxidative effects were assessed in RAW 264.7 macrophages stimulated by lipopolysaccharide (LPS). cells treated with different concentrations MOK extract 30 min prior to stimulation or without LPS indicated times. Nitric oxide (NO) production was measured using Griess reagent, while mRNA levels cytokines,...
Dysfunction of glucose metabolism is associated with the occurrence metabolic syndromes, including type 2 diabetes mellitus (T2DM). In this study, we investigated anti-diabetic effects yam aqueous extract and allantoin in high-fat-diet (HFD) streptozotocin (STZ)-induced diabetic mice mechanism action on dysfunction liver, pancreas, skeletal muscle. Male C57BL/6 were induced into a condition by HFD for 16 weeks single injection STZ (120 mg/kg) then orally administered (500 1000 or (20 50 once...
Energy-efficient processes for converting polyolefinic waste plastics into light olefins are critical mitigating environmental pollution and reducing carbon emissions. In this study, an alternative recycling scheme, the catalytic cracking of crude plastic pyrolysis oil (WPPO) over microspherical P-modified steam-treated ZSM-5 (ms-P-HZSM5-S), was demonstrated compared to a state-of-the-art commercial thermal hydrotreated naphtha range WPPO. The C2–C4 yield achieved by WPPO (56.6 wt%) exceeded...
Background. Macrophages are associated with ischemia/reperfusion (I/R) injury; however, the role of macrophages that have infiltrated into tissues remains unclear. Therefore, we investigated whether influence recovery after kidney I/R injury and affect phenomenon ischemic preconditioning, in which previous ischemia affords resistance to subsequent ischemia. Methods. Mice were subjected 30 min bilateral renal on day 0, then intravenously administered either liposome-encapsulated...
In this study, we investigated the neuroprotective effect of hairy root extract Angelica gigas NAKAI (Angelica Gigantis Radix) on transient focal cerebral ischemia in rats through regulation angiogenesis molecules.Male Sprague-Dawley were induced by a middle artery occlusion (tMCAO) for 90 min, and then orally administrated with water A. roots (AG). After 24 h reperfusion, infarction volume changes BBB permeability measured TTC Evans Blue (EB) staining. The neuronal cell damage activation...
Bekhogainsam decoction (BHID), a representative prescription for the treatment of diabetes mellitus (DM) and diabetic complications in both traditional Korean Chinese medicine, was examined its ability to ameliorate nephropathy (DN), mechanism action evaluated by metabolomics, gut microbiota, network pharmacology. In this study, male specific pathogen-free C57BL/6 mice were intraperitoneally injected with streptozotocin (STZ, 100 mg/kg) once per day 3 days consecutively, then orally...
Excessive production of inflammatory mediators, nitric oxide (NO) and proinflammatory cytokines from activated microglia has been implicated in neurodegeneration human brain diseases. Recently, it seems possible that treatment with antiinflammatory agents, including Oriental medicinal plants, might delay the progression through inhibition microglial activation. The present study evaluated effect a methanol extract Ficus religiosa leaf (MFL) on lipopolysaccharide (LPS)-induced NO cytokines,...