A5083470677- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- RNA modifications and cancer
- Environmental Toxicology and Ecotoxicology
- MicroRNA in disease regulation
- Colorectal Cancer Treatments and Studies
- Circular RNAs in diseases
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Gastric Cancer Management and Outcomes
- Ferroptosis and cancer prognosis
- Cervical Cancer and HPV Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Alzheimer's disease research and treatments
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
- Immune Cell Function and Interaction
- Colorectal Cancer Screening and Detection
- Heavy Metal Exposure and Toxicity
- Adipose Tissue and Metabolism
- Global Cancer Incidence and Screening
Zhuhai People's Hospital
2025
Jinan University
2025
Iowa State University
2020-2024
Chengdu University of Information Technology
2024
University Hospitals Seidman Cancer Center
2022-2024
Case Western Reserve University
2024
First Affiliated Hospital of Zhengzhou University
2017-2024
Southern Medical University
2010-2024
National University of Ukraine on Physical Education and Sport
2024
University School
2024
Abstract Background Cellular senescence is a complex stress response that impacts cellular function and organismal health. Multiple developmental environmental factors, such as intrinsic cues, radiation, oxidative stress, oncogenes, protein accumulation, activate genes pathways can lead to senescence. Enormous efforts have been made identify characterize (SnGs) in disease systems. However, the prevalence of senescent cells healthy human tissues global SnG expression signature different cell...
Recent evidence suggests that the Myc and Mad1 proteins are implicated in regulation of gene encoding human telomerase reverse transcriptase (hTERT), catalytic subunit telomerase. We have analyzed vivo interaction between endogenous c-Myc hTERT promoter HL60 cells with use chromatin immunoprecipitation assay. The E-boxes at proximal were occupied by exponentially proliferating but not induced to differentiate DMSO. In contrast, protein was bound differentiated cells. Concomitantly,...
Background Cancer survivors develop other chronic medical conditions because of shared risk factors and delayed effects cancer treatment. This study investigated trends in the prevalence diseases estimated their population sizes among adult United States from 2002 to 2018. Methods Using 2002‐2018 National Health Interview Survey data, this calculated age‐sex‐race/ethnicity–adjusted prevalences for following survivors: hypertension, diabetes, stroke, heart disease, obstructive pulmonary...
The authors present long-term results from a phase 2 study that assessed the efficacy of transrectal ultrasound hyperthermia plus radiation with or without androgen suppression for treatment locally advanced prostate cancer.Patients clinical T2b-T3bN0M0 disease (according to 1992 American Joint Committee on Cancer [AJCC] criteria) received treatments. After first 4 patients, 6 months were allowed. was designed assess absolute improvement in 2-year disease-free survival rate compared...
We studied here the short-term toxicity effects of Cd on oxidative state and cell death in gill freshwater crab Sinopotamon henanense. Crabs were exposed to that resulted accumulation a significant increase metallothionein (MT) level gill, but MT increased disproportionally compared with an extension exposure time. Significant changes activities superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) observed. An levels reactive oxygen species (ROS) lipid peroxidation (LPO)...
Long non-coding RNAs (lncRNAs) emerged as key regulators of diverse roles during colorectal cancer (CRC) carcinogenesis, but their specific function still remains to be explored. The present study aimed re-annotate the Affymetrix Human Exon 1.0 ST Array for defining differential lncRNAs in CRC. Their prognostic relevance was also developed screening CRC datasets E-GEOD-31737, E-MATB-829, colon dataset and E-GEOD-24550 were re-purposed searching exploring association with overall survival...
Background Polymyositis and dermatomyositis (PM/DM) are systemic autoimmune diseases with multiple organ involvements that manifest as muscular cutaneous disorders, interstitial lung disease (ILD) malignancies. However, information concerning the outcomes associated factors for PM/DM patients who hospitalized is limited. Methods We retrospectively reviewed medical charts of admitted to a Chinese tertiary referral hospital (Peking Union Medical College Hospital, PUMCH) from 2008 2014. The...
Despite the overall decreasing incidence, nasopharyngeal cancer (NPC) continues to cause a significant health burden among Asian Americans (AAs), who are fast-growing but understudied heterogeneous racial group in United States. We aimed examine racial/ethnic disparities NPC treatment, and mortality with specific focus on AA subgroups. patients aged ≥15 years were obtained from Surveillance, Epidemiology, End Results (SEER) 18 (1975-2018). AAs divided into Chinese, Filipino, Vietnamese,...
Emerging evidence indicates that resistin and fascin-1 may possess a causal role in the development of several types cancers. However, clinical significance expression colorectal cancer (CRC) tissues is unclear, there are no reports any correlation between fascin-1. Our analyses explored CRC tissue analyzed prognostic observed positive The rate strongly (27.5%) was significantly higher than normal (5.2%). Strongly related to multiple poor factors CRC, including depth tumor invasion, lymph...
Fluid intelligence (FI) involves abstract problem-solving without prior knowledge. Greater age-related FI decline increases Alzheimer's disease (AD) risk, and recent studies suggest that certain dietary regimens may influence rates of decline. However, it is uncertain how long-term food consumption affects among adults with or familial history AD (FH) APOE4 (ɛ4).