A5089696045- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Adolescent and Pediatric Healthcare
- Metabolism and Genetic Disorders
- Childhood Cancer Survivors' Quality of Life
- Genetics and Neurodevelopmental Disorders
- Neonatal and fetal brain pathology
- Genomics and Rare Diseases
- Diversity and Career in Medicine
- Bipolar Disorder and Treatment
- Pharmaceutical studies and practices
- Diet and metabolism studies
- Vitamin D Research Studies
- Long-Term Effects of COVID-19
- Medical Education and Admissions
- Muscle Physiology and Disorders
- Cardiomyopathy and Myosin Studies
- Telemedicine and Telehealth Implementation
- Neurogenetic and Muscular Disorders Research
- Patient Satisfaction in Healthcare
- Innovations in Medical Education
- COVID-19 and Mental Health
- EEG and Brain-Computer Interfaces
- Bacterial Infections and Vaccines
- Infant Development and Preterm Care
Children's Hospital of Los Angeles
2025
Keck Hospital of USC
2025
Wake Forest University
2024
Children's Healthcare of Atlanta
2024
Washington University in St. Louis
2024
University of Virginia
2024
Emory University
2024
Providence Health & Services
2024
St. Louis Children's Hospital
2024
University of Michigan
2011-2023
Objective Infantile spasms are seizures associated with a severe epileptic encephalopathy presenting in the first 2 years of life, and optimal treatment continues to be debated. This study evaluates early sustained response initial treatments addresses both clinical remission electrographic resolution hypsarrhythmia. Secondarily, it assesses whether differs by etiology or developmental status. Methods The National Spasms Consortium established multicenter, prospective database enrolling...
Febrile infection-related epilepsy syndrome (FIRES) is a newly recognized epileptic encephalopathy in which previously healthy school-aged children present with prolonged treatment-resistant status epilepticus (SE). Survivors are typically left pharmacoresistant and severe cognitive impairment. Various treatment regimens have been reported, all limited success. The ketogenic diet (KD) an alternative of may be appropriate choice for refractory SE. We report 2 who presented FIRES were placed...
The multicenter National Infantile Spasms Consortium prospective cohort was used to compare outcomes and phenotypic features of patients with infantile spasms without hypsarrhythmia.Patients aged 2 months years were enrolled prospectively new-onset spasms. Treatment choice categorization hypsarrhythmia determined clinically at each site. Response therapy defined as resolution clinical (and if present) relapse 3 after initiation.Eighty-two percent had hypsarrhythmia, but this not associated...
Summary Objective Infantile spasms ( IS ) represent a severe epileptic encephalopathy presenting in the first 2 years of life. Recommended first‐line therapies (hormonal therapy or vigabatrin) often fail. We evaluated response to second treatment for children whom initial failed produce both clinical remission and electrographic resolution hypsarhythmia whether time was related outcome. Methods The National Spasms Consortium established multicenter, prospective database enrolling infants...
More than a decade has passed since the last major workforce survey of child neurologists in United States; thus, reassessment neurology is needed, along with an inaugural assessment new related field, neurodevelopmental disabilities.The American Academy Pediatrics and Child Neurology Society conducted electronic 2015 disabilities specialists.The majority respondents participate maintenance certification, practice academic medical centers, offer subspecialty care. EEG reading epilepsy care...
Circumstances of the COVID-19 pandemic have mandated a change to standard management infantile spasms. On April 6, 2020, Child Neurology Society issued an online statement immediate recommendations streamline diagnosis and treatment spasms with utilization telemedicine, outpatient studies, selection first-line oral therapies as initial treatment. The rationale for specific guidance including follow-up assessment are provided in this manuscript. These indicated enduring if intended outlast...
The optimal evaluation and treatment of children with infantile spasms is unknown. To aid in the development a standardized approach to spasms, members Child Neurology Society were surveyed determine common practice. survey had 222 responders responder rate 18.5%. We found that diagnostic use first-line treatments varied among responders. For example, although adrenocorticotropic hormone continues be most commonly used for not due tuberous sclerosis, some clinicians corticosteroids,...
Children and adolescents with epilepsy may experience prolonged seizures in school-associated settings (eg, during transportation, the classroom, or sports activities). Prolonged evolve into status epilepticus. Administering a seizure rescue medication can abort obviate need for emergency medical services subsequent care an department. In turn, this save patients from morbidity of more invasive interventions cost escalated care. There are significant variations prescribing practices...
Background: Since the COVID-19 pandemic, telehealth has been widely adopted, and several studies have highlighted benefits of telehealth. However, there are limited in pediatric neurology with a focus on epilepsy. The objective this single-site retrospective cohort study was to examine patient experience scores versus in-person established encounters an outpatient clinic. Methods: Data were abstracted from April 1, 2020 through March 31, 2024. Variables included demographics, appointment...
Gender disparities have been demonstrated across several medical specialties, including neurology. Although women comprised most of the child neurology trainees since 2007, it is not apparent whether this demographic shift reflected in Child Neurology Society (CNS) awards and leadership. This study aimed to evaluate differences gender representation among leadership positions award recipients within CNS. The primary outcome measure was total number board director (BOD) or given by each year.
We conducted an online survey of elementary school teachers in Washtenaw County, Michigan, regarding their confidence knowledge epilepsy and preferred media or sources information about epilepsy. Eighty-three (9.3%) responded. One quarter expressed a lack ability to teach students with respond appropriately seizure. Teachers most frequently (68%) cited the Internet as primary source epilepsy, nurse parents/guardians also mentioned (55% 48%, respectively). In contrast, respondents prefer that...
In January 2019, a new plant-derived purified cannabidiol preparation, approved by the US Food and Drug Administration, became commercially available for patients ≥2 years old with Lennox-Gastaut syndrome or Dravet syndrome. Among our who were prescribed formulation, we observed several cases of thrombocytopenia therefore embarked on this study. We conducted single-center systematic chart review all pediatric (<21 old) from to August 2019. evaluated salient features patients' epilepsy...
Abstract Objective Project ECHO (Extension for Community Healthcare Outcomes), a telementoring program, utilizes lectures, case‐based learning, and an “all teach–all learn” approach to increase primary care provider (PCP) knowledge/confidence in managing chronic health conditions. The American Academy of Pediatrics (AAP) Epilepsy Comorbidities incorporated quality improvement (QI) methodology create meaningful practice change, while increasing PCP knowledge/self‐efficacy epilepsy management...