A5037311865- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Health Literacy and Information Accessibility
- Atherosclerosis and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Hepatitis C virus research
- Ethics in Clinical Research
- Autoimmune and Inflammatory Disorders Research
- Geriatric Care and Nursing Homes
- Cytokine Signaling Pathways and Interactions
- BRCA gene mutations in cancer
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Homelessness and Social Issues
- Health disparities and outcomes
- Child Abuse and Trauma
- Assistive Technology in Communication and Mobility
- Spaceflight effects on biology
- Place Attachment and Urban Studies
- Grief, Bereavement, and Mental Health
- RNA Research and Splicing
- Chronic Disease Management Strategies
- LGBTQ Health, Identity, and Policy
- Stroke Rehabilitation and Recovery
- Tryptophan and brain disorders
- Clinical practice guidelines implementation
University of Huddersfield
2021-2023
Brigham and Women's Hospital
1986-2014
Inserm
2012
Theories and Approaches of Genomic Complexity
2012
Harvard University
1995-2009
VA Boston Healthcare System
2009
New England Baptist Hospital
2008
New York University
2007
Harvard University Press
1984-2005
Nashville Oncology Associates
1958
To date, it remains impossible to guarantee that short-term treatment given a patient suffering from major depressive episode (MDE) will improve long-term efficacy. Objective biological measurements and biomarkers could help in predicting the clinical evolution of MDE are still warranted. better understand reason nearly half patients respond poorly current antidepressive treatments, we examined gene expression profile peripheral blood samples collected 16 severe 13 matched controls. Using...
Fatigue, a complex symptom, significantly affects the quality of life in many patients with systemic lupus erythematosus (SLE). To understand this phenomenon, 23 SLE and fatigue were studied. Standardized tests depression (NIMH), fatigue, exercise tolerance (ETT) on bicycle ergometer, activity obtained. At baseline, had lower maximum oxygen consumption (Vbj max) than normals (p ≪ 0.005). Adjusted for age sex, perform at 54% their expected Vo2, which is similar to published data from...
Abstract Objective A feasibility study for a trial of strategies the prevention atherosclerosis in patients with systemic lupus erythematosus (SLE) was stopped because inadequate recruitment. There is little understanding factors influencing patients' decisions about participation trials. Our goal to determine that SLE consider deciding participating trials, uncover concerns and investigate how design purpose affect decisions. Methods We conducted focus groups participants (n = 13),...
The utility of flow mediated dilation (FMD) a measure endothelial function is limited by operator dependence. Pulse amplitude tonometry (PAT) novel, less operator-dependent technique to assess function. This study compares PAT FMD in SLE and controls. Thirty women with 31 controls were enrolled. Medications, cardiovascular disease risk factors, activity (SLAM-R) damage (SLICC-DI) recorded. performed simultaneously. Endothelium-independent was assessed nitroglycerin. Average age 48.3 ± 10.1...
Abstract Objective The effectiveness of aggressive management traditional risk factors for accelerated atherosclerosis in systemic lupus erythematosus (SLE) has been advocated but not proven. We conducted a pilot, randomized, controlled trial known prevention medications (pravastatin, ramipril, aspirin, and combination B vitamin) plus individualized cardiovascular education. describe our experience recruiting retaining patients with SLE this trial. Methods Patients by American College...
Online child sexual abuse encompasses a range of offenses including the accessing, downloading, sharing and creating images abuse, often referred to as Child Sexual Abuse Material (CSAM). CSAM consumption has increased exponentially, lockdowns implemented response COVID-19 have exacerbated this problem. offenders are more likely than other sex be married, children live with partner child(ren). Policy, practice research largely considered these families within context their protective...
In the past decade, there has been growing awareness of well-being and its importance an increase in development activities or programmes aimed at improving well-being. The purpose this study is to investigate what were being offered prisoners England Wales benefits other outcomes experienced.
Abstract Fifty‐seven elderly homebound patients with arthritis and orthopedic disabilities were randomized to a goal‐oriented outreach rehabilitation program or usual treatment. Although 64% of patient goals met, there no overall significant differences in functional scores, institutionalization, contentment between treatment control periods. Twenty‐three had maintained clinical improvement at the end study some dramatically improved simple measures. The program's marginal costs modest...
In Brief Background: The internet is used by many new rheumatology patients before visiting a health care provider, and also for education, recruiting study participants, administering surveys, conducting clinical trials, data entry management of multicenter providing forum to share experiences in chat rooms. has not been nor evaluated public applications. Objectives: We the early detection referral individuals with "typical" symptoms undiagnosed rheumatoid arthritis (RA) systemic lupus...