- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Malaria Research and Control
- CAR-T cell therapy research
- Neutropenia and Cancer Infections
- Streptococcal Infections and Treatments
- Travel-related health issues
- Family and Patient Care in Intensive Care Units
- Antibiotics Pharmacokinetics and Efficacy
- Schizophrenia research and treatment
- Mosquito-borne diseases and control
- Acute Kidney Injury Research
- Nosocomial Infections in ICU
- Respiratory viral infections research
- Cardiac Arrest and Resuscitation
- Mental Health and Psychiatry
- Intensive Care Unit Cognitive Disorders
- Health, Medicine and Society
- Blood disorders and treatments
- Psychoanalysis and Psychopathology Research
- Airway Management and Intubation Techniques
- Hemodynamic Monitoring and Therapy
- Tryptophan and brain disorders
- Neuroscience of respiration and sleep
- Zoonotic diseases and public health
Université Paris Cité
2010-2024
Assistance Publique – Hôpitaux de Paris
2011-2024
Hôpital Robert-Debré
2013-2024
Mother Hospital
2023
Délégation Paris 7
2010-2021
Centre National de la Recherche Scientifique
2008-2016
Sorbonne Paris Cité
2012-2016
Aix-Marseille Université
2015-2016
Institut Pasteur
2016
Bicêtre Hospital
2016
To date, it remains impossible to guarantee that short-term treatment given a patient suffering from major depressive episode (MDE) will improve long-term efficacy. Objective biological measurements and biomarkers could help in predicting the clinical evolution of MDE are still warranted. better understand reason nearly half patients respond poorly current antidepressive treatments, we examined gene expression profile peripheral blood samples collected 16 severe 13 matched controls. Using...
Differentiating agents have been proposed to overcome the impaired cellular differentiation in acute myeloid leukemia (AML). However, only combinations of all-trans retinoic acid or arsenic trioxide with chemotherapy successful, and treating promyelocytic (also called AML3). We show that iron homeostasis is an effective target treatment AML. Iron chelating therapy induces blasts normal bone marrow precursors into monocytes/macrophages a manner involving modulation reactive oxygen species...
Forty-one children hospitalized for necrotizing pneumonia were retrospectively analyzed. Necrotizing represented 0.8% of community-acquired and 6% pneumonia. The chest radiograph revealed necrosis on admission in onethird cases. Twenty-one cases (51%) documented, including 13 Staphylococcus aureus, all Panton-Valentine leukocidin positive, 7 Streptococcus pneumoniae 1 Fusobacterium nucleatum.
Abstract The Medication Adherence Rating Scale (MARS) is one of the most widely used measurements adherence in schizophrenia (SZ), but there no available data regarding its psychometric properties homeless SZ patients (HSZ). aim this study was therefore to assess MARS a large multicenter sample HSZ subjects. This multi-centre prospective conducted following 4 French cities: Lille, Marseille, Paris and Toulouse. Three hundred fifty-three were included. 3-factor structure confirmed using...
AME Aquatic Microbial Ecology Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 57:263-277 (2009) - DOI: https://doi.org/10.3354/ame01339 Special: 'Rassoulzadegan at Villefranche-sur-Mer: 3 decades of aquatic microbial ecology' Community structure and trophic role ciliates heterotrophic nanoflagellates in Rhone River diluted mesoscale structures (NW Mediterranean Sea) Urania Christaki1,*, Claude...
<h3>Objective</h3> As few data are available on the causes of fever in children returning from international travel, authors studied presenting to a French tertiary care centre with fever. <h3>Methods</h3> Children emergency department Robert Debré Paediatric Hospital, Paris, France between July and December 2007 that occurred within 3 months stay abroad were included this retrospective study. <h3>Results</h3> The (n=538) had most commonly visited North Africa (NA) (n=214), sub-Saharan (SSA)...
Abstract Background Electronic medical records (EMR) are currently being implemented in psychiatric hospitals throughout Europe. The perceptions of health care professionals can contribute important information that may predict their acceptance and desired mode use for EMR, thus guiding EMR implementation. Aims To develop a self-administered instrument designed to assess professionals’ satisfaction regarding hospital, based only on the professional point view, according psychometric...
Purpose Toxic shock syndrome (TSS) is a rare disease responsible for significant morbidity and mortality. Intravenous immunoglobulin (IG) therapy in paediatric TSS could improve organ failure, but more consistent efficacy safety data are needed. Our objective was to determine whether randomised clinical trial (RCT) assessing intravenous IG children feasible. Methods We performed multicentre, feasibility, double-blind RCT of high-dose versus albumin 4% (control group) within the first 12...
Sickle cell disease (SCD) is one of the most frequent inherited diseases in world. Over last decades, high-income countries, an important decrease mortality have been observed due to improvement care. However, children with SCD can become critically ill and require admission Pediatric Intensive Care Units (PICU). The purpose this study was describe epidemiology admitted PICU for acute crisis identify factors associated adverse outcome (AO).
Community-acquired and nosocomial lower-respiratory-tract infections in critically ill pediatric patients require early appropriate antibiotic therapy to optimize outcomes. Using blind bronchial samples, we assessed the diagnostic performance of rapid-multiplex polymerase chain reaction (PCR) assay BioFire Pneumonia plus Panel vs. reference standard culturing with antimicrobial susceptibility testing.
Objective The World Health Organization (WHO) severity criteria for paediatric Plasmodium falciparum (Pf) malaria are based on studies in countries of endemic malaria. relevance these other remains unclear. We assessed the an industrialised country. Design Retrospective case-control study. Setting Eight French university hospitals, from 2006 to 2012. Patients Children with Pf admitted intensive care units (cases: n=55) or emergency departments (controls: n=110). Main outcome measures...