- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Muscle activation and electromyography studies
- Cerebral Palsy and Movement Disorders
- Cerebrovascular and Carotid Artery Diseases
- Transcranial Magnetic Stimulation Studies
- Balance, Gait, and Falls Prevention
- Venous Thromboembolism Diagnosis and Management
- Dementia and Cognitive Impairment Research
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury and Neurovascular Disturbances
- Spatial Neglect and Hemispheric Dysfunction
- Patient Satisfaction in Healthcare
- Advanced Neuroimaging Techniques and Applications
- Dietary Effects on Health
- Atrial Fibrillation Management and Outcomes
- Hospital Admissions and Outcomes
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Effects of Exercise
- Traumatic Brain Injury Research
- Cardiac Health and Mental Health
- Reliability and Agreement in Measurement
- Burn Injury Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Electromagnetic Fields and Biological Effects
Harvard University
2012-2024
Spaulding Rehabilitation Hospital
2011-2024
Harvard University Press
2020
Massachusetts General Hospital
2007-2019
Spaulding Hospital
2018
New York University
2018
Brigham and Women's Hospital
2018
Northwestern University
2018
Foundation for Physical Medicine and Rehabilitation
2018
Dr. Jeffrey Thomas Stroke Shield Foundation
2018
Background and Purpose— We aim to compare demographics functional outcomes of patients with stroke in a variety vascular territories who underwent inpatient rehabilitation. Such comparative data are important prognostication, rehabilitation, healthcare planning, but literature is scarce isolated. Methods— Using collected prospectively over 9-year period, we studied 2213 individuals sustained first-ever ischemic strokes were admitted an rehabilitation program. Strokes divided into anterior...
High-dosage motor practice can significantly contribute to achieving functional recovery after a stroke. Performing rehabilitation exercises at home and using, or attempting use, the stroke-affected upper limb during Activities of Daily Living (ADL) are effective ways achieve high-dosage in stroke survivors. This paper presents novel technological approach that enables 1) detecting goal-directed movements performance ADL, so timely feedback be provided encourage use affected limb, 2)...
The need to develop patient-specific interventions is apparent when one considers that clinical studies often report satisfactory motor gains only in a portion of participants. This observation provides the foundation for "precision rehabilitation". Tracking and predicting outcomes defining recovery trajectory key this context. Data collected using wearable sensors provide clinicians with opportunity do so little burden on patients. approach proposed paper relies machine learning-based...
The effect of age on functional outcome after stroke remains uncertain. Many studies have found that younger patients do better than older patients, whereas others minimal or no rehabilitation outcomes. We examined the advancing FIM trade mark gain, length stay, stay efficiency, and home discharge in 979 at a long-term acute care hospital. strong relationship increasing to poorer all measures for with admission (AFIM) score <40, variable those AFIM 40-80, >80.
Objective Acute care readmission risk is an increasingly recognized problem that has garnered significant attention, yet the reasons for acute in inpatient rehabilitation population are complex and likely multifactorial. Information on both medical comorbidities functional status routinely collected stroke patients participating rehabilitation. We sought to determine whether a more robust predictor of readmissions compared with using large, administrative data set. Methods A retrospective...
Rehabilitation specialists have shown considerable interest for the development of models, based on clinical data, to predict response rehabilitation interventions in stroke and traumatic brain injury survivors. However, accurate predictions are difficult obtain due variability patients' interventions. This study aimed investigate use wearable technology combination with data monitor recovery process assess responsiveness treatment an individual basis.Gaussian Process Regression-based...
Selective serotonin reuptake inhibitors (SSRIs) are currently widely used in the field of neuromodulation not only because their anti-depressive effects but also due to ability promote plasticity and enhance motor recovery patients with stroke. Recent studies showed that fluoxetine promotes after stroke through its on serotonergic system enhancing outputs facilitating long term potentiation, key factors neural plasticity. However, little is known regards exact mechanisms underlying these...
Background. Although recent evidence has shown a new role of fluoxetine in motor rehabilitation, results are mixed. We conducted randomized clinical trial to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with increases upper limb function stroke. Methods. Twenty-seven hemiparetic patients within 2 years ischemic stroke were into 3 groups: Combined (active rTMS + fluoxetine), Fluoxetine (sham or Placebo placebo fluoxetine). Participants received 18 sessions...
Current functional assessment instruments in stroke rehabilitation are often setting-specific and lack precision, breadth, and/or feasibility. Computer adaptive testing (CAT) offers a promising potential solution by providing quick, yet precise, measure of function that can be used across broad range patient abilities multiple settings. CAT technology yields precise score selecting very few relevant items from large diverse item pool based on each individual's responses. We demonstrate the...
Haley SM, Ni P, Coster WJ, Black-Schaffer R, Siebens H, Tao W: Agreement in functional assessment: graphic approaches to displaying respondent effects. Am J Phys Med Rehabil 2006;85:747–755. Objective: The objective of this study was examine the agreement between respondents summary scores from items representing three content areas (physical and mobility, personal care instrumental, applied cognition) within Activity Measure for Postacute Care (AM-PAC). We compare proxy vs. patient report...
The aim of the study was to assess relation between cerebrovascular function early after aneurysmal subarachnoid hemorrhage onset and functional rehabilitation outcomes.Observational cohort patients (n = 133) admitted 49), discharged home 52), or died before discharge 10). We obtained hemodynamic markers cerebral autoregulatory from blood flow velocities in middle artery arterial pressure waveforms, recorded daily on days 2-4 symptom onset, independence measure (FIM) scores FIM efficiency...
Frequent and objective monitoring of motor recovery progression holds significant importance in stroke rehabilitation. Despite extensive studies on wearable solutions this context, the focus has been predominantly evaluating limb activity. This study aims to address limitation by delving into a novel measure wrist kinematics more intricately related patients' capacity.
The study herein summarized was focused on the development of a method to derive reliable estimates quality movement stroke survivors via analysis wearable sensor data. Data collected from 34 subjects while they performed battery functional movements that are part standard clinical assessment. assessed using Functional Ability Scale, validated scale based visual observation patterns by expert. Two sensors were positioned stroke-affected wrist and sternum, respectively. Wearable data...