A5065212821- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Hormonal Regulation and Hypertension
- Adipose Tissue and Metabolism
- Neonatal Health and Biochemistry
- Clinical Nutrition and Gastroenterology
- Respiratory Support and Mechanisms
- Exercise and Physiological Responses
- Bee Products Chemical Analysis
- Renin-Angiotensin System Studies
- Intestinal Malrotation and Obstruction Disorders
- Neonatal and fetal brain pathology
- Vitamin D Research Studies
- Muscle metabolism and nutrition
- Nutrition, Genetics, and Disease
- Cancer and Skin Lesions
- Pharmacogenetics and Drug Metabolism
- Spectroscopy Techniques in Biomedical and Chemical Research
- Genetic and rare skin diseases.
- Ocular Disorders and Treatments
- Spectroscopy and Chemometric Analyses
- Magnesium in Health and Disease
Kocaeli Üniversitesi
2023
Bursa Uludağ Üni̇versi̇tesi̇
2023
Istanbul University-Cerrahpaşa
2020
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2014-2020
Nightingale Hospital
2020
Istanbul Bilim University
2020
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2019
Adnan Menderes University
2016-2017
Middle East Technical University
2001-2016
Ondokuz Mayıs University
2010
In recent years, Fourier Transform Infrared (FT-IR) spectroscopy has had an increasingly important role in the field of pathology and diagnosis disease states. current study, FT-IR together with cluster analysis were used as a diagnostic tool discrimination diabetic samples from control ones rat kidney plasma membrane apical sides (brush-border membranes), liver microsomal membranes Extensor digitorum longus (EDL) Soleus (SOL) skeletal muscle tissues. A variety alterations spectral...
Diabetes Mellitus (DM) is a metabolic disorder, characterized by abnormally high blood glucose levels due to decreased secretion or effectiveness in function of insulin. Having role carbohydrate and lipid metabolism, skeletal muscle affected the absence insulin diabetic conditions. This current study reports application Fourier transform infrared (FTIR) spectroscopy determination macromolecular alterations streptozotocin (STZ)-induced rat Soleus (SOL) muscles, which highlight promise this...
Objective. To analyze neonatal morbidity and mortality rates of late-preterms to compare them with their term counterparts in a tertiary care unit Turkey.Study design. The study included 252 late-preterm newborns (34 0/7–36 6/7 weeks' gestational age), admitted Neonatal Intensive Care Unit the first 24 h life between January 2005 June 2007 born same hospital period time. Babies major congenital and/or chromosomal abnormalities were excluded.Results. rate was 2.3% late-preterms. None died....
To analyze neonatal morbidity and mortality rates of late-preterms to compare them with their term counterparts in a tertiary care unit Turkey.The study included 252 late-preterm newborns (34 0/7--36 6/7 weeks' gestational age), admitted Neonatal Intensive Care Unit the first 24 h life between January 2005 June 2007 born same hospital period time. Babies major congenital and/or chromosomal abnormalities were excluded.The rate was 2.3% late-preterms. None died. Compared terms, 11 times more...
To assess the incidence and severity of acute kidney injury (AKI) evaluate risk factors that predict AKI in asphyxiated infants receiving therapeutic hypothermia.Infants ≥36 weeks' gestation diagnosed with moderate-to-severe perinatal asphyxia received hypothermia were reviewed retrospectively (n = 166). Modified Acute Kidney Injury Network criteria used to diagnose AKI. The results compared who did not develop AKI.AKI developed 49 (29.5%) infants, whom 22 had stage I, 13 II, 14 III overall...
The relation between protein structural alterations and tissue dysfunction is a major concern as fibrillation and/or aggregation due to has been reported in many disease states. In the current study, Fourier transform infrared microspectroscopic imaging used investigate diabetes-induced changes on secondary structure macromolecular content streptozotocin-induced diabetic rat liver. Protein were predicted using neural network approach utilizing amide I region. Moreover, role of selenium...
Objective To determine the effect of two different feeding strategies on time to achieve full enteral and incidence intolerance in preterm infants with birth weight ≤1250 g.Methods A prospective randomized trial (NCT02913677) conducted at a tertiary level neonatal intensive care unit. Preterm g were randomly allocated either prolonged minimal nutrition (MEN) which feed volumes not increased for five days or early advancement groups advanced by 20–25 ml/kg/d until 150 volume was achieved. The...
Advances in diagnostic and therapeutic methods have led to a paradigm shift the management of bronchopulmonary dysplasia (BPD). The lack evidence-based data this area has variations clinical practice. aim study was identify these differences compare them with recommendations based on pathophysiology. designed as an observational online survey neonatologists from level 3 4 neonatal intensive care units caring for premature infants at increased risk BPD born before 28 weeks' gestation....
BackgroundVariation in the renin–angiotensin system (RAS) and salt-sensitivity genes may influence effect of thiazides on risk diabetes. We assessed whether polymorphisms RAS influenced diabetes associated with thiazides.
Rhamnetin is a flavonoid that has antioxidant, anti-inflammatory and anti-cancer effects. Nucleolar-organizing regions are the ribosomal genes region. We aimed to identify whether rhamnetin an effect on cell proliferation AgNOR proteins may be used for detection of therapeutic benefits drugs new metabolites, which have potential being cancer treatments.Twenty-four mice with Ehrlich's ascites carcinoma (EAC) were randomly assigned three main groups as positive control, 2 3 treated...
Alterations in microstructure and mineral features can affect the mechanical chemical properties of bones their capacity to resist forces. Controversial results on diabetic bone content have been reported little is known about structural alterations collagen, maturation apatite crystals, carbonate bone. This current study first report organic cortical, trabecular, growth plate regions rat femurs using Fourier transform infrared (FT-IR) microspectroscopy Vickers microhardness test. Femurs...
To describe the design, recruitment and baseline characteristics of participants in a community pharmacy based pharmacogenetic study antihypertensive drug treatment.Participants enrolled from population-based Pharmaco-Morbidity Record Linkage System.We designed nested case-control which we will assess whether specific genetic polymorphisms modify effect drugs on risk myocardial infarction. In this study, cases (myocardial infarction) controls were recruited through pharmacies that...
The current study aims to determine lipid profiles in terms of the content and structure skeletal muscle adipose tissues better understand characteristics juvenile-onset spontaneous obesity without high fat diet induction. For purposes this study, (longissimus, quadriceps) (inguinal, gonadal) 10-week-old male DBA/2J Berlin mouse inbred (BFMI) lines (BFMI856, BFMI860, BFMI861) fed with a standard breeding were used. Biomolecular composition was determined using attenuated total reflection...
Endotracheal intubation is a frequent procedure performed in neonates with respiratory distress. Clinicians use different methods to estimate the insertion depth, but, unfortunately, improper results are very high. In this study, we aimed compare two (Tochen's formula = weight kilograms + 6 cm; and nasal septum-tragus length [NTL] 1 cm) used determine endotracheal tube (ETT) depth.Infants who had indications were enrolled study. The was fixed using Tochen (Tochen group) or NTL cm (NTL...
Diabetes mellitus (DM) is a chronic disorder of carbohydrate, fat and protein metabolism, which characterized by defective insulin secretory response. Skeletal muscle takes role in determination carbohydrate lipid therefore; it one the target tissues diabetes. Herein this study, application Fourier Transform Infrared (FTIR) spectroscopy diabetic skeletal Extensor Digitorum Longus (EDL) will be presented highlight promise technique medical research. Type I DM was induced rats injection...
Previous studies demonstrated that magnesium sulfate is associated with better neurological outcome and decreased cerebral palsy rates in preterm newborns. The aim of this study to assess the effects antenatal on neurodevelopmental outcomes infants.Preterm newborns a gestational age <32 weeks whose mothers were diagnosed preeclampsia extracted from hospital records files retrospectively. assessment was performed at 2 years by developmental pediatrician. results infants exposed compared...
Introduction. We assessed the influence of genetic polymorphisms in renin-angiotensin system on risk diabetes associated with use angiotensin II receptor blockers and angiotensin-converting enzyme (ACE) inhibitors. Materials methods. performed a matched case-control study among antihypertensive drug users. Pharmacy records questionnaires were used to ascertain incident (cases), use, factors. Controls did not (yet) have diabetes.We genotyped ACE (G4656C, which is complete linkage...
Background: Several retrospective studies have reported an increase in necrotizing enterocolitis (NEC) during the 48 h following red blood cell (RBC) transfusion. Whether withholding enteral feeding transfusion decreases risk of transfusion-associated acute gut injury (TRAGI) preterm infants is unclear.Study design and methods: In this pilot study, 112 with gestational age ≤32 weeks and/or birth weight ≤1500 g were randomly assigned to (NPO) or continuance (FED) RBC Primary outcome measure...
Severe neonatal hyperbilirubinemia is an important cause of morbidity and mortality in developing countries. The aim was to assess etiologic reasons for development severe define risk factors exchange transfusion acute bilirubin encephalopathy (ABE) Şanlıurfa located the southeast region Turkey.An observational cohort study included 115 infants with ≥35 weeks gestation admitted diagnosis a period 18 months. Potential associated ABE were analyzed.Among infants, 67 (58.3%) received 45 (39.1%)...
Lichen striatus (LS) is an uncommon dermatosis characterised by a linear inflammatory papular eruption. It frequently seen in children and rarely adults. We present this study 49-year-old female patient who was diagnosed as LS, which occurs after bite bumblebee. As we know, it the first case of LS reported
Aim: This short communication aims to evaluate the relation in between drug exposure time and early pregnancy regarding gestational weeks.Methods: The study covers referrals made Department of Pharmacology for a teratogenic consultation 3-year period. From recordings pregnant women, last menstrual period starting date medication were used determine prescription with regard weeks.Results: In all three years, potentially was prescribed more frequently 3rd, 4th 5th weeks (in 15–35 days...