A5004702866- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Neonatal Health and Biochemistry
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Sepsis Diagnosis and Treatment
- Infant Health and Development
- Clinical Nutrition and Gastroenterology
- Cleft Lip and Palate Research
- Neonatal and fetal brain pathology
- Congenital Anomalies and Fetal Surgery
- Pregnancy and preeclampsia studies
- Metabolism and Genetic Disorders
- Inflammatory Biomarkers in Disease Prognosis
- Syphilis Diagnosis and Treatment
- Congenital Heart Disease Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Pediatric Pain Management Techniques
- Thyroid Disorders and Treatments
- Urological Disorders and Treatments
- Vitamin D Research Studies
- Gastroesophageal reflux and treatments
Bursa Uludağ Üni̇versi̇tesi̇
2014-2025
Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2018-2025
Sağlık Bilimleri Üniversitesi
2018-2025
University of Health Science
2018-2025
Bursa Technical University
2020-2024
Izmir University
2023
University of Health Sciences
2022
Istanbul University-Cerrahpaşa
2009-2020
Haseki Eğitim ve Araştırma Hastanesi
2020
Bülent Ecevit University
2015
Necrotizing enterocolitis (NEC) is a gastrointestinal emergency of the neonatal period. The aim this study was to demonstrate use multistrain and multispecies probiotic on morbidities mortality. organized as randomized controlled, prospective in premature infants (≤32 week ≤1500 gram). ready commercial preparations which contain multi-combined probiotics Lactobacillus rhamnosus (4.1x108 cfu) + casei (8.2x108 plantorum Bifidobacterium animalis together with 383 mg fructooligosaccharides 100...
Caffeine is a proven medication used for the prevention and treatment of apnea in premature infants, offering both short- long-term benefits. International guidelines provide range recommendations regarding preterm population eligible caffeine prophylaxis, including timing, dosage, duration treatment. Our national guidelines, published prior to most recent updates international recommend use citrate starting from first day after delivery infants with gestational age <28 weeks. For up 32...
Objective: Germinal matrix hemorrhage and intraventricular (GMH-IVH) is currently the most significant cause of brain damage mortality seen in preterm infants. The aim this study was to evaluate predictive value mean platelet volume (MPV) diagnosing GMH-IVH mortality. Method: A retrospective-cohort infants with a gestational age <32 weeks or birthweight <1500gr who were admitted Neonatal Intensive Care Unit conducted between January 2020 2022. These then classified into two groups...
Germinal matrix kanaması-intraventriküler kanama, özellikle erken doğumların önemli bir komplikasyonu olup pretermlerde görülen beyin hasarının en sık nedenidir. Etiyolojisi karmaşık ve multifaktöriyel yenidoğanlarda morbidite mortalite nedenlerindendir. Hastanemiz Yenidoğan Yoğun Bakım Ünitesinde doğum ağırlığı 1500 gramın gestasyon yaşı 32 haftanın altında doğan toplam 391 yenidoğan (n=119 prematüre germinal n=27 ileri evre kanama tanılı) çalışmaya dahil edilmiştir. Çalışmaya edilen...
Advances in diagnostic and therapeutic methods have led to a paradigm shift the management of bronchopulmonary dysplasia (BPD). The lack evidence-based data this area has variations clinical practice. aim study was identify these differences compare them with recommendations based on pathophysiology. designed as an observational online survey neonatologists from level 3 4 neonatal intensive care units caring for premature infants at increased risk BPD born before 28 weeks' gestation....
Background: Transient tachypnea of the newborn (TTN) is traditionally viewed as a disorder delayed lung fluid clearance, but emerging evidence suggests inflammatory involvement. Aim: This study investigated systemic indices [(systemic immune-inflammation index (SII-i), inflammation response (SIR-i), neutrophil-to-lymphocyte ratio (NL-r), and platelet-to-lymphocyte (PL-r)] underlying mechanisms in TTN pathogenesis for first time. Methods: retrospective case–control included 199 neonates (123...
Abstract Background Evidence for impact of breast milk and fecal microbial content on jaundice (BMJ) is accumulating. We studied the influence bacterial feces BMJ also effects probiotic supplementation course jaundice. Methods Seventy‐seven patients 35 healthy controls were enrolled. Breast samples collected. Thirty‐seven received probiotics. Quantitative DNA was measured six bacteria. concentrations, bilirubin levels, decline in weight gain compared. Results concentrations five species...
The positive effects of steroids on lung development are well known, and 1,25-dihydroxy vitamin D3 has been shown to exert fetal development.We aimed investigate the relationship between 25-hydroxyvitamin D [25(OH)D] levels respiratory distress syndrome (RDS) in premature infants.Infants aged ≤32 gestational weeks who were admitted neonatal intensive care unit (NICU) during 1 year enrolled this prospective study. 25(OH)D obtained at time admission NICU. Patients divided into three groups...
This national cross-sectional survey aimed to assess the iodine status in pregnant women and their offspring, also demonstrate regional differences by measuring urinary concentration (UIC). For each woman her newborn a questionnaire was prepared with basic facts as age, parity number or birth weight additional information regarding thyroid diseases, use of iodized salt household, extra supplementation during pregnancy, education level wage income. The target population represented 1444 who...
Abstract Background Parenteral nutrition ( PN ) has been widely used in preterm infants. The lipid solutions for , however, are associated with oxidative stress and morbidity. aim of this study was to compare the effectiveness a new‐generation emulsion SMOFL ipid) olive‐oil based prevention ‐associated damage. Methods Preterm infants < 32 weeks gestational age were included prospective randomized study. All SMOF or (ClinOleic). Lipid peroxidation products evaluated all In addition, total...
Late-onset sepsis (LOS) remains an important cause of morbidity and mortality in preterm infants. In this study, our aim was to investigate the red-cell distribution width (RDW) levels during a LOS episode, its association with type growing microorganism mortality.Preterm infants culture-proven their neonatal intensive care unit stay were enrolled. Red-cell obtained first 4 h postnatal life at onset compared for these time frames. The study cohort divided into two groups according...
Preterm infants need nutritional and medical requirements in accordance with the physiologic maturity at birth maintaining optimal postnatal corporal cerebral growth is one of main targets caregivers. However, only a few strategies exist to improve outcomes pathogen-rich nutrient-poor neonatal intensive care unit environment. In this pilot study, we hypothesize that synbiotics may enhance brain growth, which reflected indirectly by an increase head circumference through several signalling...
Abstract Objectives Congenital syphilis can cause severe morbidities such as hydrops fetalis, preterm birth, low birth weight, hepatosplenomegaly, pneumonia, hypoglycemia, etc., and mortality. Despite hypoglycemia being reported in congenital hyperinsulinism, only one case was described. In this article, we aimed to present a newborn with born syphilitic mother who diagnosed persistent hyperinsulinemic focal lesion during follow-up. Case presentation A female patient weight of 2,450 g the 32...
Mannose-binding lectin, which belongs to the collectin family, is an acute-phase reactant that activates complement system. This study aimed investigate effect of MBL2 gene polymorphism on short-term outcomes in preterm infants.Infants <37 gestational weeks who were admitted neonatal intensive care unit during a two-year period enrolled this prospective study. The neonates categorized into two groups according their genotypes. Normal genotype was defined as wild-type (AA genotype), whereas...
Objective: This study aimed at assessing the serial carboxyhemoglobin (COHb) levels in preterm infants during first week of life and their variation with late-onset sepsis (LOS). Study Design: Infants <37 gestational weeks were categorized into two groups according to presence culture proven LOS. Serial COHb obtained life, onset LOS episode, upon blood negativity response antibiotics. Result: Overall 207 enrolled. A episode resulted a significant increase (p < 0.001), which decreased normal...
Purpose: Retinopathy of prematurity (ROP), an abnormal proliferation retinal vessels in premature infants with low birth weight, develops due to many factors. This study investigated a possible correlation between haematological parameters and ROP development. Method: included 189 without 128 ROP. All were born at 35 weeks’ gestation or earlier, had CBC drawn within 72 hours birth, haemogram data for the first month. Haemoglobin (Hb), haematocrit (Hct), mean corpuscular volume (MCV),...
Introduction: Glutathione synthetase (GSS) deficiency is an autosomal recessive disorder (frequency < 1/1,000,000) with different varyingly severe clinical manifestations that include metabolic acidosis, hemolytic anemia, hyperbilirubinemia, neurological disorders and sepsis. Case report: This infant was small for gestational age, had bilateral subependymal pseudocysts increased echogenicity of the basal ganglia. GSS confirmed by genetic analysis. The patient also unilateral right femur...
IntroductionWe investigated the association between low 25-hydroxyvitamin D (25-OHD) levels and late-onset sepsis (LOS) in preterm infants (<37 weeks). Methods: Infants with culture-proven LOS were study group, without controls. 25-OHD compared these groups. Low vitamin was defined as ≤15 ng/ml. Maternal to their infant's level. Results: 108 included. The group significantly younger (p = 0.02) lower < 0.001). Multivariable logistic regression analyses revealed that 7.159 (95%CI:...
Objective: Preterm infants are prone to increased bilirubin burden and display adverse outcomes if left unmonitored; therefore, predicting an production is of paramount importance.Methods: We aimed evaluate carboxyhemoglobin (COHb) levels in moderate (GA: 320/7–336/7) late preterm 340/7–366/7) assess whether this molecule could be used as early predictor phototherapy requirement.Results: A total 221 were enrolled the study. On admission, who received significantly higher than that did not...
Abstract Background The clinical phenotypes of carnitine palmitoyltransferase type-2 deficiency (CPT2D) are classified into lethal neonatal, severe infantile and muscle forms. rarest form is the neonatal form. Case presentation patient was hypotonic bradycardic at admission. Blood urea nitrogen creatinine were high. He had polycystic kidneys, patent foramen ovale aortic valve insufficiency. Cranial magnetic resonance imaging (MRI) revealed increased signal intensities in periventricular...
Aim: Late-onset sepsis (LOS) persists to be a crucial reason of morbidity and mortality in preterm infants. Studying the effect neutrophil-lymphocyte ratio (NLR) value predicting LOS episode relation with type growing microorganism were aim this study.Material Methods: Preterm infants classified as two groups accordance having culture proven during stay neonatal intensive care unit. Premature was defined study group no-LOS control group. Study is consisting subgroups terms type. NLR values...