A5024022330- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiac Health and Mental Health
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Takotsubo Cardiomyopathy and Associated Phenomena
- Systemic Lupus Erythematosus Research
- Pregnancy and preeclampsia studies
- Cardiac electrophysiology and arrhythmias
- Sex and Gender in Healthcare
- Blood Pressure and Hypertension Studies
- Atherosclerosis and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Cardiovascular Effects of Exercise
- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Birth, Development, and Health
- Coronary Artery Anomalies
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
Cedars-Sinai Smidt Heart Institute
2016-2025
Cedars-Sinai Medical Center
2016-2025
University of Florida
2012-2024
Rutgers, The State University of New Jersey
2019-2023
New York University
2022
Brigham and Women's Hospital
2022
University of California, Los Angeles
2015-2021
The Lundquist Institute
2021
Computational Diagnostics (United States)
2021
Florida College
2021
Myocardial infarction with nonobstructive coronary arteries (MINOCA) occurs in 6% to 15% of myocardial infarctions (MIs) and disproportionately affects women. Scientific statements recommend multimodality imaging MINOCA define the underlying cause. We performed optical coherence tomography (OCT) cardiac magnetic resonance (CMR) assess mechanisms MINOCA.
Background— Women with signs and symptoms of ischemia no obstructive coronary artery disease often have microvascular dysfunction (CMD), diagnosed by invasive reactivity testing (CRT). Although traditional noninvasive stress imaging is normal in CMD, cardiac MRI may be able to detect CMD this population. Methods Results— Vasodilator was performed 118 women suspected who had undergone CRT 21 asymptomatic reference subjects. Semi-quantitative evaluation the first-pass perfusion images...
The mechanistic basis of the symptoms and signs myocardial ischaemia in patients without obstructive coronary artery disease (CAD) evidence microvascular dysfunction (CMD) is unclear. aim this study was to mechanistically test short-term late sodium current inhibition (ranolazine) such subjects on angina, perfusion reserve index, diastolic filling. Randomized, double-blind, placebo-controlled, crossover, trial with CMD [invasive reactivity testing or non-invasive cardiac magnetic resonance...
Artificial intelligence (AI) has been developed for echocardiography1-3, although it not yet tested with blinding and randomization. Here we designed a blinded, randomized non-inferiority clinical trial (ClinicalTrials.gov ID: NCT05140642; no outside funding) of AI versus sonographer initial assessment left ventricular ejection fraction (LVEF) to evaluate the impact in interpretation workflow. The primary end point was change LVEF between or final cardiologist assessment, evaluated by...
Women with coronary microvascular dysfunction (CMD) and no obstructive artery disease (CAD) have increased rates of heart failure preserved ejection fraction (HFpEF). The mechanisms HFpEF are not well understood. Ectopic fat deposition in the myocardium, termed myocardial steatosis, is frequently associated diastolic other metabolic diseases. We investigated prevalence steatosis women CMD subclinical HFpEF. In 13 women, including eight reference controls five evidence (left ventricular...