Network environments give computer users the option of employing distributed information and services to complete a task. However, gathering using in networks requires knowing exactly what kinds are required for task, where they are, how can be obtained or utilized. Tracking down answers these questions difficult, time consuming tasks users. Mobile agent technology is expected release them from having do so. Instead, "intelligent" mobile agents will comprehend user's requirements, search...

Abstract Methanol and water extracts of 30 Indonesian medicinal plants were tested for inhibitory activity on avian myeloblastosis virus (AMV)‐reverse transcriptase (RT). The most potent inhibition was shown by Loranthus parasiticus (whole plant), Helicteres isora (fruit), Terminalia belerica (fruit peel), Strobilanthes crispus (leaves) Woodfordia floribunda (flower leaves). Two kinds template‐primers, (rA) n ‐(dT) 12–18 (rC) ‐(dG) examined polymerization reaction but the stronger in...

To predict the rate of prostate cancer detection on biopsy more accurately, performance deep learning using a multilayer artificial neural network was investigated.A total 334 patients who underwent multiparametric magnetic resonance imaging before ultrasonography guided transrectal 12-core were enrolled in analysis. Twenty-two non-selected variables, as well selected ones by least absolute shrinkage and selection operator (Lasso) regression analysis stepwise logistic analysis, input into...

A splice variant of androgen receptor (AR), AR-V7, lacks in androgen-binding portion and leads to aggressive cancer characteristics. Reverse transcription-polymerase chain reactions (PCRs) subsequent nested PCRs for the amplification AR-V7 prostate-specific antigen (PSA) transcripts were done whole blood patients with prostate male controls. With primary reverse transcription PCRs, PSA detected 4.5% 4.7% cancer, respectively. messenger RNA (mRNA) was positive 43.8% castration-sensitive 48.1%...

ObjectiveTo assess the clinicopathologic factors influencing survival in patients with metastatic urothelial carcinoma undergoing salvage chemotherapy.

Abstract Objectives To predict the rate of prostate cancer detection on biopsy more accurately, performance deep learning utilizing a multilayer artificial neural network was investigated. Materials and methods A total 334 patients who underwent multiparametric magnetic resonance imaging before ultrasonography-guided transrectal 12-core were enrolled in analysis. Twenty-two non-selected variables as well selected ones by least absolute shrinkage selection operator (Lasso) regression analysis...

We tested the hypothesis that stimulation by electro-resection of bladder tissue induces stem cells in repair process.After primary transurethral resection a tumor and surrounding (TUR-Bt), second TUR-Bt was performed. Tissues excised were immunohistochemically stained for Oct4, marker pluripotency, CD90 CD73, markers mesenchymal stromal cells, when no remained.Oct4B protein sporadically cytoplasm interstitial four out eight cases. CD73 are upregulated vascular endothelial without CD45...

Fourteen adult patients undergoing elective major abdominal surgery were divided into two groups. One group received epidural and general anesthesia (epidural group), 20 ml of 0.125% bupivacaine 2 mg morphine administered epidurally about 30 min before the end operation for post‐anesthetic analgesia. The other (control group) alone with nitrous oxide, oxygen enfiurane. Flow‐directed pulmonary arterial radial catheters inserted preoperatively, hemodynamic, respiratory, neuroendocrine...

Objectives. Dutasteride, a dual 5α-reductase inhibitor, is used to treat benign prostatic hyperplasia. Nevertheless, its histopathological effects on the morphometrics of blood vessels and glands are still controversial. The aim here was assess dutasteride in cases hyperplasia retrospective study. Methods. Patients with more than 40 cm(3) volume were administered 0.5 mg daily or left untreated prior receiving transurethral resection prostate. Images sections stained hematoxylin/eosin...

A strictly anaerobic bacterium capable of metabolizing sennosides was isolated from human feces and identified as Bifidobacterium sp., named strain SEN. The hydrolyzed B to sennidins via sennidin 8-monoglucosides, respectively. Among nine species having beta-glucosidase activity, only dentium B. adolescentis metabolized sennoside B, suggesting that the sennoside-metabolizing bacteria produce a novel type hydrolyzing sennidins.

To investigate the cause of adult-onset primary noncommunicating hydrocele testis, protein expressions water channel aquaporins (AQPs) 1 and 3 in tunica vaginalis were assessed. Frozen specimens from patients with testis control male nonhydrocele subjected to Western blot analysis for detection AQP1 AQP3 proteins. Paraffin-embedded sections histochemically stained anti-AQP1 anti-AQP3 antibodies as well an anti-podoplanin antibody stain lymphatic endothelia. Hydrocele fluid was biochemical...

Seventeen thiopaeonimetabolin-I adducts were obtained as mixtures of diastereoisomers after incubation paeoniflorin with Lactobacillus brevis in the presence various thiols. Four compounds, 8-(n-hexylthio)- (8), 8-cyclopentylthio-, 8-(p-tolyl)thio- and 8-benzoylthio- (18) paeonimetabolins, showed 100% protection against pentylenetetrazole-induced convulsions at doses 0.125, 0.25, or 0.50 mmol/kg, relative to valproic acid (100% 1.5 mmol/kg). For 8 18, principle anticonvulsant activity...

The aim of this study was to evaluate the efficacy and toxicity combination docetaxel, ifosfamide cisplatin as salvage chemotherapy after failure standard cisplatin-based regimens for metastatic urothelial carcinoma.We prospectively administered patients with carcinoma refractory from 2003 2013. Patients who had received only adjuvant and/or neoadjuvant were excluded. Eligible every 28 days docetaxel 60 mg/m(2) on Day 1, 1.0 g/m(2) Days 2-6 20 2-6. primary endpoints progression-free survival...

This paper deals with the "ubiquitous personal agent" that distinctively provides information services to individual user depending on his/her contexts. In this details about agent technology as well its effectiveness are discussed. The latter has been confirmed by verification tests using home appliances already available in domestic market.

Abstract Various conditions including distal renal tubular acidosis (dRTA) can induce stone formation in the kidney. dRTA is characterized by an impairment of urine acidification nephron. caused variations genes functioning intercalated cells SLC4A1/AE1/Band3 transcribing two kinds mRNAs encoding Cl − /HCO3 exchanger erythrocytes and that expressed α-intercalated (kAE1). With acid-loading test, 25% urolithiasis patients were diagnosed with incomplete dRTA. In erythroid intron 3 containing...

Background Laparoscopic surgery has spread quickly during the past twenty years, and become one of important treatments in field colorectal surgery. Recently, natural orifice transluminal endoscopic (NOTES) been studied as next generation minimally-invasive surgery, but feasibility safety NOTES method have not evaluated. In such a situation, single-incision laparoscopic attracted interest from surgeons worldwide. However, yet standardized. Methods From February 2010, colectomy was performed...

This study examined the effects of single-nucleotide polymorphisms (SNPs) on development bladder cancer, adding longest-held occupational and industrial history as regulators. The genome purified from blood was genotyped, followed by SNP imputation. In genome-wide association (GWAS), several patterns industrial/occupational classifications were added to logistic regression models. test between cancer calculated genetic score for each gene region evaluated (gene-wise analysis). GWAS gene-wise...

Bifidobacterium sp. strain SEN was isolated and characterized by hydrolytic conversion of sennosides to sennidins (Akao et al., Appl. Environ. Microbiol., 60, 1041 (1994)). The sennoside-hydrolyzing capacity the disappeared following addition glucose media in spite good bacterial growth potent activity hydrolyzing p-nitrophenyl β-D-glucopyranoside (pNPG). In a fructose-containing medium, no such suppressing effect shown. Following 10 h incubation 50 mM potassium phosphate buffer (pH 7.4),...