Neslihan Özyurt

ORCID: 0000-0002-1404-8983
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About
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Research Areas
  • Colorectal Cancer Treatments and Studies
  • Lung Cancer Treatments and Mutations
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal Tumor Research and Treatment
  • PI3K/AKT/mTOR signaling in cancer
  • Dietary Effects on Health
  • HER2/EGFR in Cancer Research
  • Palliative Care and End-of-Life Issues
  • Pancreatic and Hepatic Oncology Research
  • Breast Cancer Treatment Studies
  • Childhood Cancer Survivors' Quality of Life
  • Cardiac tumors and thrombi
  • Vascular Tumors and Angiosarcomas
  • Prostate Cancer Treatment and Research
  • Cancer Cells and Metastasis
  • Sarcoma Diagnosis and Treatment
  • Nutrition and Health in Aging
  • Acute Myeloid Leukemia Research
  • Inflammatory mediators and NSAID effects
  • Cancer, Lipids, and Metabolism
  • Celiac Disease Research and Management
  • Esophageal Cancer Research and Treatment
  • Economic and Financial Impacts of Cancer
  • Intraperitoneal and Appendiceal Malignancies
  • Microscopic Colitis

Ordu University
2024-2025

Ankara University
2018-2024

Giresun University
2021-2022

State Hospital
2022

Regional Medical Center
2021

Istanbul Medipol University
2021

Recep Tayyip Erdoğan University
2013-2021

Cukurova University
2021

Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2021

Gazi Hastanesi
2021

Millions of Muslims fast from dawn until dusk during the annual Islamic holy month Ramadan. Most studies evaluating biochemical changes in diabetic patients Ramadan showed little glycemic control. In this study, our aim was to assess impact fasting on control with type 2 diabetes.We examined 122 diabetes (82 female, 40 male, age 56.93 ± 9.57 years) before and after 66.4% were treated oral antidiabetic (OAD) alone, 6.5% a combination insulin plus OAD 19.7% alone. 88 fasted (26.98 5.93 days)....

10.1055/s-0033-1347247 article EN Experimental and Clinical Endocrinology & Diabetes 2013-08-09

Background/Objectives: Following the results of phase 3 KEYNOTE-522 trial, U.S. Food and Drug Administration approved pembrolizumab, a humanized IgG4 kappa monoclonal antibody, in combination with neoadjuvant chemotherapy as new standard care for high-risk early-stage triple-negative breast cancer (TNBC). This retrospective, multicenter study Türkiye assessed real-world efficacy safety pembrolizumab combined TNBC. Methods: The included 108 patients treated between 2021 2023 across 14...

10.3390/cancers16193389 article EN Cancers 2024-10-03

Introduction: A significant proportion of cervical cancer (CC) patients are diagnosed at a locally advanced stage. Concurrent chemoradiotherapy (CCRT) is the cornerstone treatment for with CC. However, role adjuvant chemotherapy (AC) after CCRT controversial. In this study, we analyzed efficacy AC in stage III CC patients. Methods: We performed multicenter, retrospective analysis 139 International Federation Gynecology and Obstetrics treated whom 45.3% received AC. Our goal was to determine...

10.1159/000521980 article EN Oncology Research and Treatment 2022-01-01

Adjuvant chemoradiotherapy (CRT) is the optimal management strategy in resectable gastric cancer. There a debate about efficacy of more aggressive CRT plus chemotherapy regimens adjuvant setting. This study aimed to compare docetaxel-cisplatin-fluorouracil (DCF) versus fluorouracil-folinic acid (FUFA) stage III

10.4103/jcrt.jcrt_1009_20 article EN Journal of Cancer Research and Therapeutics 2024-04-01

The studies evaluating the impact of Her2 levels in neoadjuvant setting have conflicting data. aim study was to evaluate prognostic status early triple negative breast cancer(TNBC). In TNBC patients who were treated with chemotherapy (NAC) and surgery analyzed retrospectively. primary analyze status(Her2-0 Her2-low) on pathological complete response (pCR). secondary objectives disease free survival (DFS) overall (OS). 620 female cancer evaluated. 427 (68.9%) had Her2-0 193(31.1%) her2-low...

10.1038/s41598-024-75293-5 article EN cc-by-nc-nd Scientific Reports 2024-10-09

Perioperative FLOT regimen is a standard of care in locally advanced operable gastric and GEJ adenocarcinoma. We aimed to determine the efficacy, prognostic factors perioperative chemotherapy real-life tumors.The data patients who were treated with retrospectively analyzed from 34 different oncology centers Turkey. Baseline clinical demographic characteristics, pretreatment laboratory values, histological molecular characteristics recorded.A total 441 included study. The median age our study...

10.55730/1300-0144.5404 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2022-01-01

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.32.p387 article EN Endocrine Abstracts 2013-04-01

Objectives Head and neck soft tissue sarcomas (HNSTSs) are a heterogeneous group of rare tumors. Surgical resection with negative margins remains the standard primary treatment for patients HNSTS. The role chemotherapy (CT) radiotherapy (RT) controversial. In this multicenter study, we aimed to demonstrate real-world assessing prognostic factors effect adjuvant modalities in adult HNSTS treated upfront surgery. Methods We included total 47 who underwent curative-intent between 2000 2019....

10.7759/cureus.13324 article EN Cureus 2021-02-13

Aim: To assess the efficacy and tolerability of first-line treatment options for hormone-refractory prostate cancer patients with visceral metastases. Materials & methods: The records 191 diagnosed metastases were analyzed retrospectively. Results: Docetaxel was administered to 61.2% (n = 117), abiraterone 14.2% 27) enzalutamide 9.4% 18) as treatment. median survival receiving docetaxel, during period 15 (95% Cl: 12.9-17) months, 6 1.8-10.1) months 11 0.9-23.1) (p 0.038), respectively....

10.2217/fon-2020-1032 article EN Future Oncology 2021-02-26

e15551 Background: In this study, we aimed to investigate the efficiency and safety of initiation regorafenib at different doses in mCRC Methods: Between January 2013 2018, study retrospectively reviewed patients (pts) who treated with after failure fluoropyrimidine, irinotecan oxaliplatin +/- biologic agent from 7 centers Turkey Results: The median age 112 pts was 54.85 years (range, 28-78) 63 (56.3%) male. At time diagnosis; there were 12 (10.7%) ECOG PS 0, 68 (60.7%) 1, 32 (28.6%) 2....

10.1200/jco.2018.36.15_suppl.e15551 article EN Journal of Clinical Oncology 2018-05-20

Kaposi sarkomu (KS), human herpes virüs 8 (HHV-8) ile ilişkili anjiyo proliferatif bir hastalıktır (1).En sık Akdeniz havzası Orta ve Doğu Avrupa'daki bireylerde görülür (2,3).KS'nin klasik, endemik, post transplant epidemik olmak üzere dört çeşidi vardır (4)

10.4274/atfm.25733 article TR Journal of Ankara University Faculty of Medicine 2018-12-01

130 Background: Tyrosine kinase inhibitors (TKI) are the most common oral drugs in cancer patients. Similarly, proton pump (PPI) commonly used to relieve dyspeptic symptoms patients with cancer. However, gastric pH levels may affect absorption of TKI through gastrointestinal system. all TKIs do not have same chemical structure, and rate each depends on their solubility different levels. Limited data is available about clinical outcomes concomitant use PPI regorafenib metastatic colorectal...

10.1200/jco.2022.40.4_suppl.130 article EN Journal of Clinical Oncology 2022-01-19

The aim of this multicentre retrospective study was to compare the efficacy adjuvant chemotherapy regimens both with and without oxaliplatin tumor sidedness in stage IIB (pT4aN0) colon cancer patients. This included patients who underwent curative surgery received chemotherapy. were divided into two groups (one one oxaliplatin) overall survival (OS) right- left-sided tumors. population 298 (median age: 57) whom 69.1% male. Forty-four per cent these (n = 131) diagnosed right-sided cancer....

10.1080/1120009x.2022.2040770 article EN Journal of Chemotherapy 2022-02-17

Neoadjuvant chemotherapy (NACT) in gastroesophageal junction (GEJ) and gastric cancer (GC) was shown to improve survival recent studies. We aimed share our real-life experience of patients who received NACT compare the efficacy toxicity profile different regimens country. This retrospective multicentre study included locally advanced GC GEJ between 2007 2021. Relation CT pathological evaluation were analysed. A total 794 from 45 oncology centers Turkey included. Median age at time diagnosis...

10.1080/1120009x.2022.2073159 article EN Journal of Chemotherapy 2022-05-17

Abstract Aim To compare survival outcomes, response rates, and adverse events (AEs) in proton pump inhibitor (PPI) user non-user patients with metastatic colorectal cancer (mCRC) treated regorafenib. Methods We included 272 mCRC regorafenib this study. Patients were divided into two categories according to their status of PPI use. The primary endpoint was overall (OS). secondary endpoints time treatment failure (TTF), safety. exclude immortal bias analyses, we compared all patients. Results...

10.21203/rs.3.rs-1840215/v1 preprint EN cc-by Research Square (Research Square) 2022-07-29

Abstract Aim To compare survival outcomes, response rates, and adverse events (AEs) in proton pump inhibitor (PPI) user non-user patients with metastatic colorectal cancer (mCRC) treated regorafenib. Methods We included 272 mCRC regorafenib this study. Patientswere divided into two categories according to their status of PPI use. The primary endpoint was overall (OS). secondary endpoints were time treatment failure (TTF), safety. exclude immortal bias analyses, we compared all patients....

10.21203/rs.3.rs-1840215/v2 preprint EN cc-by Research Square (Research Square) 2022-08-24
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