Ömer Acar

ORCID: 0000-0003-4408-1976
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Research Areas
  • Breast Cancer Treatment Studies
  • Advanced Breast Cancer Therapies
  • HER2/EGFR in Cancer Research
  • Cancer-related Molecular Pathways
  • Male Breast Health Studies
  • Chronic Lymphocytic Leukemia Research
  • Cardiovascular Disease and Adiposity
  • MRI in cancer diagnosis
  • Prostate Cancer Treatment and Research
  • Metastasis and carcinoma case studies
  • Retinal Diseases and Treatments
  • Colorectal Cancer Surgical Treatments
  • COVID-19 and healthcare impacts
  • Multiple and Secondary Primary Cancers
  • Cancer Cells and Metastasis
  • Gastric Cancer Management and Outcomes
  • COVID-19 and Mental Health
  • Bladder and Urothelial Cancer Treatments
  • Healthcare professionals’ stress and burnout
  • Cancer Diagnosis and Treatment
  • Esophageal Cancer Research and Treatment
  • Cancer, Lipids, and Metabolism
  • Inflammatory Biomarkers in Disease Prognosis
  • Retinal Imaging and Analysis
  • Breast Lesions and Carcinomas

Manisa Celal Bayar University
2022-2025

Mardin Artuklu University
2024-2025

There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which oncologists prefer patients with disease progression under CDKi. In addition, we show the effectiveness of systemic treatments CDKi and whether there a survival difference between hormonal (monotherapy vs. mTOR-based).A total 609 from 53 centers were included study....

10.1186/s12885-023-10609-8 article EN cc-by BMC Cancer 2023-02-10

Ribociclib, palbociclib and abemaciclib are currently approved CDK4/6 inhibitors along with aromatase as the first-line standard-of-care for patients hormone receptor-positive, HER2-negative metastatic breast cancer.

10.2217/fon-2022-1287 article EN Future Oncology 2023-03-01

Abstract Background Cancer patients are in the high-risk group of getting COVID-19 infection and experiencing a severe course. Anxiety cancer about how they pass this pandemic process changes health system would influence their treatment has increased together with pandemic. Influence on psychology is also subject needed to be investigated as well its course prognosis. Thus, it aimed measure fear levels by validated scale. Patients accepting fill Fear (FCV-19S) scale were included our study....

10.1186/s43045-022-00181-5 article EN cc-by Middle East Current Psychiatry 2022-01-28

In this Turkish Oncology Group study, we aimed to evaluate the effectiveness of trastuzumab emtansine (TDM1) in adjuvant treatment early-stage human epidermal growth factor receptor-2 (HER2)-positive breast cancer with residual disease using real-life data. A total 13 centers participated study between September 2019 and October 2024. Patients HER2-positive who underwent surgery after completing neoadjuvant chemotherapy HER2-targeted therapies had invasive or axillary lymph nodes received...

10.1097/cad.0000000000001717 article EN Anti-Cancer Drugs 2025-03-31

e16261 Background: Ampullary adenocarcinoma is a rare cancer for which there are no standard adjuvant treatment recommendations due to the lack of randomized clinical trials. The primary aim this analysis investigate efficacy FOLFIRINOX in patients with resected ampullary adenocarcinoma. Methods: This multicenter retrospective cohort study was conducted at 15 institutions Turkey between August 2007 and January 2024, involving 211 resected, non-metastatic receiving chemotherapy various...

10.1200/jco.2025.43.16_suppl.e16261 article EN Journal of Clinical Oncology 2025-05-28

Purpose:It is estimated that type 2 diabetes mellitus affects 530 million people worldwide and 10.5 per cent of these patients have diabetic retinopathy. This study aims to investigate the predictive value cardiometabolic control, GGT malnutrition-related inflammation markers for predicting Diabetic retinopathy prevalence prognosis. Materials Methods:Type Diabetes Mellitus who were consecutively admitted Internal Ophthalmology outpatient clinics included in this study. Clinical,...

10.31362/patd.1419095 article EN cc-by-nc Pamukkale Medical Journal 2024-03-11

Objective: To investigate the effect of haemoglobin, albumin, lymphocyte, and platelet (HALP) score (Haemoglobin, Albumin, Lymphocyte, Platelet count) on survival as a new prognostic factor in metastatic bladder cancer.

10.29271/jcpsp.2023.12.1405 article EN Journal of College of Physicians And Surgeons Pakistan 2023-12-01

Abstract Objective: Contrast-enhanced mammography (CEM) is a relatively inexpensive and convenient new imaging method obtained by administering enhanced iodinated contrast agent using the dual-energy technique to evaluate tumor neovascularity. CEM provides similar morphological physiological information breast magnetic resonance (MRI), gold standard for detecting cancer. We aimed compare techniques, which have increased in popularity recent years, with MRI, has been date, histopathological...

10.21203/rs.3.rs-4073077/v1 preprint EN cc-by Research Square (Research Square) 2024-03-27

The studies evaluating the impact of Her2 levels in neoadjuvant setting have conflicting data. aim study was to evaluate prognostic status early triple negative breast cancer(TNBC). In TNBC patients who were treated with chemotherapy (NAC) and surgery analyzed retrospectively. primary analyze status(Her2-0 Her2-low) on pathological complete response (pCR). secondary objectives disease free survival (DFS) overall (OS). 620 female cancer evaluated. 427 (68.9%) had Her2-0 193(31.1%) her2-low...

10.1038/s41598-024-75293-5 article EN cc-by-nc-nd Scientific Reports 2024-10-09

Purpose: A significant portion of patients diagnosed with breast cancer are over the age 65. Elderly often excluded from prospective clinical trials due to comorbidities. Clinicians have different treatment management options for elderly patients. Under-treatment or over-treatment may negatively affect outcomes and prognosis. There few data guide decisions. We present pathological features followed in our center. Materials Methods: retrospective review files about surgically treated was...

10.17826/cumj.1529238 article EN Çukurova medical journal (Online)/Çukurova medical journal 2024-11-22
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