A5067747982- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Cancer Treatment and Pharmacology
- Lung Cancer Research Studies
- Inflammatory Biomarkers in Disease Prognosis
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Venous Thromboembolism Diagnosis and Management
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiopharmaceutical Chemistry and Applications
- Renal and related cancers
- Pancreatic and Hepatic Oncology Research
- Brain Metastases and Treatment
- Nonmelanoma Skin Cancer Studies
- Sarcoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Polyomavirus and related diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urinary and Genital Oncology Studies
Afyon Kocatepe University
2013-2024
Antalya IVF
2019-2024
Antalya Bilim University
2024
Pfizer (United States)
2024
Hacettepe University
2024
Afyonkarahisar Sağlık Bilimleri Üniversitesi
2019-2024
Pfizer (United Kingdom)
2024
Roche (Switzerland)
2024
AstraZeneca (Brazil)
2024
Novartis (Switzerland)
2024
The objective of this study was to evaluate the blood platelet-lymphocyte ratio (PLR) for its prognostic value in patients with metastatic renal cell cancer (RCC).We retrospectively reviewed 100 diagnosed RCC previously treated tyrosine kinase inhibitors from three centers. We assessed pretreatment PLR and other clinical laboratory parameters based on univariate multivariate analyses.Median progression-free survival (PFS) 7.3 months median overall (OS) 15.3 months. Multivariate analysis...
Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease. Endothelial dysfunction, an early reversible feature the pathogenesis atherosclerosis, is associated increased vascular smooth muscle tone, arterial stiffening, intima-media thickness. Coronary flow velocity reserve noninvasive test showing endothelial function epicardial coronary arteries microcirculatory function. The aim study was to investigate carotid...
Background: Treatment of anemia is an important issue in the palliative care setting. Blood transfusion generally used for this purpose supportive care. However place blood terminally ill cancer cases less far established. Objective: We aimed to outline use transfusions and find impact on survival patients with advanced very near death. Design: Patients dying 2010-2011 were included study. retrospectively collected data including age, type cancer, duration last hospitalisation, ECOG...
Introduction. Most common metastasis sites of breast cancer are the lungs, bones, liver, and brain, whereas uterine involvement by metastatic disease is rare. Metastatic carcinoma uterus usually originates from other genital sites, most commonly being ovaries. Invasive lobular spreads to gynecologic organs more frequently than invasive ductal carcinoma. Case Report. A 57-year-old postmenopausal woman was diagnosed with 2 years ago modified radical mastectomy performed. Pathological...
Breast cancer is the most frequently diagnosed in women worldwide and second cause of cancer-related mortality. A total 20-30% patients with early-stage breast develop recurrence within first 5 years following diagnosis. Trastuzumab significantly improves overall survival disease-free (DFS) human epidermal growth factor receptor 2 (HER2)-positive early locally advanced cancer. This study aimed to determine factors that affect DFS adjuvant transtuzumab therapy. 62 treated trastuzumab for were...
Objectives/Hypothesis The aim of this study was to investigate the potential protective effect curcumin on paclitaxel‐induced ototoxicity in rats by means immunohistochemical and histopathological analysis distortion product otoacoustic emissions (DPOAEs). Study Design Animal study. Methods Forty Sprague‐Dawley were randomized into five groups. Group 1 administered no paclitaxel during Groups 2, 3, 4 5 mg/kg paclitaxel; 200 curcumin; paclitaxel, followed a day later intraperitoneally once...
The main goal of this study was to examine whether the occurrence hypothyroidism during sunitinib therapy in patients with metastatic renal cell carcinoma (mRCC) is associated a better outcome.The enrolled 81 pathologically proven mRCC who were treated between March 2008 and June 2013.Thyroid function evaluation comprised (free-thyroxine) FT4 thyroid-stimulating hormone (TSH) before treatment at day 1 each 6-week cycle. Survival analysis performed using Kaplan-Meier method, differences among...
An increasing number of patients receive palliative chemotherapy near the end life. The aim this study is to evaluate aggressiveness in Turkish individuals life.Patients diagnosed with solid tumors and died from 2010 2011 medical oncology department Akdeniz University were included study. Data about diagnosis, treatment details imaging procedures collected.Three hundred seventy-three people stage IV our clinic. Eighty-nine (23.9%) underwent last month life while 39 (10.5%) received 14 days....
The prognostic significance of the neutrophil-to-lymphocyte ratio for progression free survival in patients with metastatic renal cell carcinoma is unclear.We retrospectively reviewed 45 diagnosed RCC previously treated tyrosine kinase inhibitors from two centers, Akdeniz University Hospital and Afyon Kocatepe University. value pretreatment neutrophil- tolymphocyte ratio, other clinical laboratory parameters were assessed by univariate multivariate analysis.Median (PFS) was 13.9 months [95%...
Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal benign which generally seen in children and young adults. It especially located the lungs. In histopathological examination, neoplastic fusiform cells originating from subtype of accessory immune system are called fibroblastic reticulum (Kouichi Youichirou, 2008). Although IMT histopathologically benign, imaging methods show its tendency for local recurrence invasion. most cases, it may not be possible to make distinction whether...
The aim of the study was to investigate association between molecular subtypes and patterns relapse in breast cancer patients who had undergone curative surgery.We retrospectively evaluated 1,350 with relapses after surgery 1998 2012 from referral centers Turkey. Patients were divided into 4 biological according immunohistochemistry grade: triple negative, HER2 overexpressing, luminal A B.The percentages A, B, HER2-overexpressing, triple-negative 32.9% (n = 444), 34.9% 471), 12.0% 162),...
The American Joint Committee on Cancer (AJCC) published a new staging system (7th edition) in 2009. In our study, we evaluated the survival results and prognostic factors among T4 local advanced non-small cell lung cancer (LA-NSCLC) patients large heterogeneous group, accordance with this system.We retrospectively files of 122 N0-3 M0 LA-NSCLC patients, identified according to system, treated at two centers between November 2003 June 2012. Variables correlating univariate p<0.20 were later...
Pilomatrix carcinoma is an extremely rare skin tumor derived from basaloid cells in the hair follicles; it often exhibits locally aggressive behavior with a tendency toward local recurrence. The average age of occurrence 45 years, and there appears to be male female incidence ratio 4:1. Although pilomatrix carcinomas are predominantly identified neck scalp, studies literature reporting other development sites, including upper extremities, torso popliteal fossa. If diagnosed at early stage,...
<b><i>Background:</i></b> Colorectal cancer (CRC) is a rare disease amongst children and adolescents. Previous studies have reported number of differences between children/adolescents, young adults, adult patients with CRC. However, none these compared age groups according to their clinicopathologic prognostic characteristics. In the current study, we compare three groups. <b><i>Methods:</i></b>A total 173 (1.1% 15,654 patients) CRC (≤25 years)...
AMAÇ: Bu çalışmada Afyon Kocatepe Üniversitesi’nde meme kanseri nedeniyle takip edilmekte olan hastalarda tamamlayıcı ve alternatif tedavi (TAT) kullanım sıklığının TAT ile ilgili uygulamaların belirlenmesi incelenmesi amaçlanmıştır.GEREÇ VE YÖNTEM: Çalışmamıza Üniversitesi Tıp Fakültesi Hastanesi, Tıbbi Onkoloji Polikliniği Fizik Tedavi Rehabilitasyon Ana Bilim Dalı’na başvuran toplam 70 kanserli hasta dahil edilmiştir. Hastaların sosoyodemografik özellikleri ile, kullanılan yöntemlerine...
Mucosal melanoma (MM) is a rare type of cancer that differs significantly from cutaneous melanoma. In this study, we aimed to evaluate clinical and demographical characteristics, prognoses factors influencing survival, treatment alternatives, features different subtypes the patients. The patients were followed up with treated in centers due their diagnoses MM. We retrospectively analyzed data 107 who diagnosed MM 14 institutions Turkey. mean age was 64.5 years. Of patients, 47 % female 53...