A5055133980- Sarcoma Diagnosis and Treatment
- Urologic and reproductive health conditions
- Cutaneous Melanoma Detection and Management
- Reconstructive Surgery and Microvascular Techniques
- Soft tissue tumor case studies
- Testicular diseases and treatments
- Genetic and rare skin diseases.
- Tracheal and airway disorders
- Neuroendocrine Tumor Research Advances
- Medical Imaging and Pathology Studies
- Reconstructive Facial Surgery Techniques
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Immunotherapy and Immune Responses
- Gastric Cancer Management and Outcomes
- Research on Leishmaniasis Studies
- Autoimmune Bullous Skin Diseases
- Mycobacterium research and diagnosis
- CAR-T cell therapy research
- Urticaria and Related Conditions
- Nonmelanoma Skin Cancer Studies
- Blood transfusion and management
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- S100 Proteins and Annexins
Akdeniz University
2014-2024
Konya Numune Hastanesi
2023
Antalya IVF
2022
Aesthetic Surgery Center
2016
Akdeniz University Hospital
2014-2015
Isparta University of Applied Sciences
2013
Bullous pemphigoid (BP) is an autoimmune disease characterized by subepidermal blistering. Based on previous work, IgG autoantibodies directed against BP180 are thought to be the primary pathogenic agent in BP. In addition these autoantibodies, however, most BP patients produce IgE class that also react with BP180, and total levels often elevated this disease. To directly test whether pathogenic, 6 ng of isolated from two normal sera were injected into human skin grafted onto athymic, nude...
The composite tumors of the liver are very rare, including coexistence HCC (hepatocellular carcinoma) with NEC (neuroendocrine carcinoma). rare occurrence these necessitates more reported cases in order to fully understand their clinical characteristics, behaviors and treatments. Herein is described an incidental collision tumor HCC-NEC, along a review literature focusing on clinicopathological findings prognosis. presented here was found incidentally hepatectomy specimen 56-year-old man who...
Nowadays, postoperative flap perfusion impairment still occurs in free surgery; despite several studies on microcirculatory physiology, the effect of hemodilution is extremely controversial. The aim this study was to investigate impact acute normovolemic and hypervolemic incidence survival rate a microsurgical rat model.Forty female Wistar rats were divided into four groups 10 each: group 1, superficial inferior epigastric artery elevated until femoral vessels isolated, sectioned,...
Background: Oesophageal squamous cell carcinoma (ESCC) is endemic in the Eastern Anatolian region of Turkey. The present study was performed to identify risk factors for ESCC that specifically reflect demography and nutritional habits individuals living this region. Materials Methods: following parameters were compared 208 patients 200 control region: age, sex, place living, socioeconomic level, education smoking, alcohol intake, habits, food preservation methods. Results: mean age 56.2...
Recent studies have shown that the tumor microenvironment significantly influences behavior of solid tumors. In this context, Accumulated data suggests pathological evaluation budding (TB), desmoplastic reaction (DR), and tumor-infiltrating lymphocytes (TILs) may be crucial in determining gastrointestinal tract. Regarding gastric adenocarcinoma (GAC), although some results suggest TB TILs effective course disease, do not agree. Moreover, very few investigated relationship between DR...
Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal benign which generally seen in children and young adults. It especially located the lungs. In histopathological examination, neoplastic fusiform cells originating from subtype of accessory immune system are called fibroblastic reticulum (Kouichi Youichirou, 2008). Although IMT histopathologically benign, imaging methods show its tendency for local recurrence invasion. most cases, it may not be possible to make distinction whether...
The American Joint Committee on Cancer (AJCC) published a new staging system (7th edition) in 2009. In our study, we evaluated the survival results and prognostic factors among T4 local advanced non-small cell lung cancer (LA-NSCLC) patients large heterogeneous group, accordance with this system.We retrospectively files of 122 N0-3 M0 LA-NSCLC patients, identified according to system, treated at two centers between November 2003 June 2012. Variables correlating univariate p<0.20 were later...
Pilomatrix carcinoma is an extremely rare skin tumor derived from basaloid cells in the hair follicles; it often exhibits locally aggressive behavior with a tendency toward local recurrence. The average age of occurrence 45 years, and there appears to be male female incidence ratio 4:1. Although pilomatrix carcinomas are predominantly identified neck scalp, studies literature reporting other development sites, including upper extremities, torso popliteal fossa. If diagnosed at early stage,...
Background: We defined melanoma distribution in a large series of Turkish patients and evaluated the prognostic parameters melanomas. Materials Methods: A total 1574 patients' data was retrospectively collected at 18 centers Turkey. Demographic characteristics were questioned noted. Prognostic parametres based on sentinel lymph node involvement. Results: Mean age 56.7 (4-99) years. While 844 (53.6%) cases male, 730 (46.4%) female. One thousand four hundred forty-seven (92%) invasive 127 (8%)...
There are reports that acrochordon (skin tag), the most common fibroepithelial tumor of skin, may be associated with metabolic syndrome components, particularly insulin metabolism disorders. However, to best our knowledge, there is no study examining its association resistance and tissue levels insulin-like growth factor 1 receptor (IGF-1R) 2 (IGF-2R).Thirty patients at least one in their body who had known history diabetes mellitus a control group comprised 30 individuals or were included....
Abstract: Defects in the interleukin 12 (IL‐12)/interferon gamma (IFN‐γ) pathway result Mendelian susceptibility to mycobacterial disease (MSMD). IL‐12 receptor beta 1 (IL‐12Rβ1) deficiency, most common form of MSMD, is associated with weakly virulent mycobacteria and salmonella. Infections patients this deficiency are extraintestinal, or septicemic, recurrent infections nontyphoid salmonellae. Here we report a case an IL‐12Rβ1 cutaneous leukocytoclastic vasculitis due Salmonella enteritidis .
Surfactant proteins (SP-A and SP-D) were originally described in the lung; however, they are also present prostate. Purpose of this study, therefore, was to determine how surfactant altered prostate adenocarcinomas (PCa) find out any connection exists between their expressions staining patterns, prostate-specific antigen (PSA) values, Gleason score, age, tumor volume tumor, node, metastases (TNM) clinical stage.Thirty-five tissue samples obtained during radical prostatectomy. All specimens...
Objective: This study aims to experimentally investigate the efficiency of Ankaferd Blood Stopper (ABS) on early and long- term bone healing its effects surfaces.Materials Methods: 30 adult male Wistar albino rats were used in study.These randomly divided into three groups, bilaterally defects created femur each rat.A 3.0 mm deep monocortikal circular defect was with a diameter trephine drill proximal part femur.0.5ml ABS applied experimental group while control left untreated.Group1,...
The protooncogene c-kit encoding transmembrane tyrosine kinase receptor protein plays an important role in the signal transduction pathway that regulates cellular growth and repair. Gene product KIT overexpression has been shown a number of different neoplasms, particularly mastocytosis gastrointestinal stromal tumours (GIST). morphologic similarity uterine mesenchymal GIST, presence normal tissue, suggests sarcomas may have same overexpression. purpose this study was to determine ovarian...
Ameloblastoma is a benign but locally aggressive tumor of odontogenic epithelial tissue. Reports radiotherapy treatment modalities are limited in the literature. A thirty-five year old male presented with complaints headache radiating to his face for about six months and impaired vision. The patient’s Positron Emission Tomography (PET) showed mass left maxillary sinus extending nasal cavity invading adjacent tissues. An R2 (macroscopic residual tumor) surgical resection performed debulk...
Pulmonary alveolar microlithiasis is characterized by the presence of calcospherites in spaces.Sporadic cases are more common, but disease also presents an inherited familial form.The greatest number reported from Europe and especially Turkey.We present a 43-year-old female with complaints dyspnea for many years.She had suspicious history pulmonary microlithiasis.The surgical lung biopsy specimen appeared gritty firm.Histological sections showed diffuse involvement parenchyma innumerable...
Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two later he Crohn's disease (CD) diarrhea episodes which were unresponsive the treatment. Depending on active gastrointestinal bleeding and perforation underwent total colectomy. Despite immunoglobulin antiviral therapies, general condition of deteriorated died in postoperative seventh day. Laboratory analysis was...
Median raphe cysts present anywhere between the external urethral meatus and anus. The can occur at parameatus, glans penis, penile shaft, scrotum, or perineum. Perianal region is an extremely rare location for these lesions. Here we a 50-year-old male patient who presented with cystic, fluctuant lesion, located 12 o’clock in perianal region. Microscopic examination revealed cystic lesion keratinized nonkeratinized stratified squamous epithelium, pseudostratified ciliated scattered goblet...
Introduction. In colorectal carcinoma, tumoral tissues infiltrate with various immune/inflammatory cells along their invasive margins and the increased S100A8/A9 expression in these immune infiltrating tumor has recently been demonstrated. We examined as a potential therapeutic target treatment of carcinoma. Materials Methods. The current study included sample 80 patients diagnosed CRC (30 cases distant metastasis, 30 lymph node 20 no metastasis). Peritumoral intratumoral S100A8 S100A9...
Background: Several studies showed the detrimental effect of pedicle torsion on flap survival; however, impact hemodilution in this peculiar condition has never been investigated. This study evaluated acute normovolemic and hypervolemic survival a perforator with twisted model. Methods: Sixty-three female Wistar rats were divided into three groups 21 each: group 1, superficial inferior epigastric artery flap, which was elevated bilaterally transposed back to abdominal wall different angles...
Cutaneus leishmaniasis, a chronic self-limited disease of the skin, is usually caused by Leishmania Tropica. It endemic in Southeastern Anatolia. The definitive diagnosis depends on demonstration parasites smear and culture or its identification tissue section. This study aimed to evaluate clinical histopathological skin lesions cutaneous leishmaniasis cases Antalya, Turkey.Our included 28 patients diagnosed with at Pathology Department Akdeniz University Medical Faculty. Histopathological...