A5033702098- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Colorectal and Anal Carcinomas
- Brain Metastases and Treatment
- Colorectal Cancer Surgical Treatments
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Family Support in Illness
- Hepatocellular Carcinoma Treatment and Prognosis
- Central Venous Catheters and Hemodialysis
- Monoclonal and Polyclonal Antibodies Research
- Peptidase Inhibition and Analysis
- Chemotherapy-induced cardiotoxicity and mitigation
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Neurological disorders and treatments
- Health Literacy and Information Accessibility
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
Kocaeli Üniversitesi
2019-2023
Bahçeşehir University
2019
Ministry of Health
2013-2014
Istanbul Eye Hospital
2013-2014
Dokuz Eylül University
2011-2013
Dicle University
2013
Gaziantep University
2013
Marmara University
2013
Fırat University
2013
We aimed to identify the incidence of cardiac events with capecitabine treatment.The study included 52 patients (median age 59 years) cancer treated at our Medical Oncology Clinic between 2009 and 2010. Cardiac from treatment were classified into 4 groups: symptoms, physical signs, electrocardiography (ECG) findings, severe adverse effects.The received either single-agent or a combination chemotherapy including capecitabine. After initiation capecitabine, 18 (34.6%) had new onset...
To evaluate the clinicopathologic characteristics and treatment outcomes of young patients with colorectal cancer (CRC).Between May 2003 June 2010, 76 were found eligible for this retrospective study. Age, sex, presenting symptoms, acute presentation, family history, presence polyps, histologic features, localization stage tumor, outcomes, time site recurrence, sites metastasis, survival recorded from patient files.Seventy-six (55.3% male) a median age 23 years evaluated. Patients evaluated...
Lapatinib is the first dual tyrosine kinase inhibitor of human epidermal growth factor receptor type 2 (HER2/neu) and (EGFR). The present study evaluated efficacy tolerability combination lapatinib capecitabine in patients with metastatic breast cancer (MBC) who progressed after therapy trastuzumab, a taxane and/or anthracycline. A total 203 median age 48 years (range: 25-82 years) were retrospectively 11 centres between September 2007 May 2011. All had HER2-positive MBC progressing...
Background: To investigate epidermal growth factor receptor (EGFR) gene mutations in patients with non-small cell lung cancer (NSCLC) and to analyze any relationship clinicopathological features prognosis. Materials Methods: EGFR exons 18-21 48 specimens of paraffin-embedded tumor tissue from NSCLC were amplified by PCR, followed direct sequencing analysis links Results: detected 18 (42.6%) NSCLC. There 9 cases exon 20, 7 19 2 21. Mutations more frequently observed women (5/7 pts, 71.4%)...
<b><i>Background:</i></b> The aim of this study is to determine the relationship between survival outcomes and biological subtype in breast cancer patients with brain metastases. <b><i>Methods:</i></b> We retrospectively evaluated clinical data from 422 metastases 2001 2011 referral centers Turkey. population was divided into four subtypes according their hormone receptor status HER2 expression. <b><i>Results:</i></b>...
<b><i>Background:</i></b> We aimed to investigate the impact of adjuvant systemic therapy with modern chemotherapy combinations on survival outcomes in patients resected liver-confined metastases from colorectal carcinomas, and whether addition bevacizumab (BEV) provides further benefit. <b><i>Methods:</i></b> A total 229 consecutive who underwent resection for liver were retrospectively analyzed. <b><i>Results:...
The aim of this study was to assess the use 5-fluorouracil (5-FU), leucovorin and oxaliplatin (FOLFOX) regimens in clinical practice according their efficacy toxicity.Patients who received oxaliplatin-containing after curative resection for colorectal carcinoma from 10 different oncology centers between May 2004 December 2009 were included study. All patients treated with FOLFOX regimens. Patients rectal also chemoradiotherapy 5-FU 2 cycles a regimen.The median age 56 years (range 17-78). Of...
The frequency of bilateral breast cancer is 1.4-11.0% among all cancers. It can present as synchronous (SC) or metachronous (MC). Data regarding clinical course are scarce. In this study, we therefore evaluated demographic, pathological and characteristics, treatments responses in cases; making distinctions between metachronous-synchronous comparing with historic one-sided data for the same parameters.One hundred fifty cases from ten different centers 2000 2011 were retrospectively scanned....
<b><i>Background:</i></b> Colorectal cancer (CRC) is a rare disease amongst children and adolescents. Previous studies have reported number of differences between children/adolescents, young adults, adult patients with CRC. However, none these compared age groups according to their clinicopathologic prognostic characteristics. In the current study, we compare three groups. <b><i>Methods:</i></b>A total 173 (1.1% 15,654 patients) CRC (≤25 years)...
This study examined the incidence rates of cancer cases (averages for 2006-2010) and relationships with environmental radioactivity levels. Soil water samples were collected from provincial district centers Van city outdoor gamma doses determined using a portable scintillation detector. Gross alpha beta, (226)Ra, (232)Th, (40)K activities measured in both tap soil samples. Although high stomach esophagus cancers have been reported previously underlying reasons not hitherto defined....
To evaluate the factors that have an impact on development of brain metastasis in patients with breast cancer.Among who were followed-up and treated for cancer between January 2000 2010, ones included to analysis. Metastatic without metastasis, which had similar duration follow-up median age as control group. Both group compared prognostic predictive terms relationship or survival.There a total 63 female metastatic researchers enrolled same number In univariate analysis, significant finding,...
Cancer diagnosis affects all the relatives living with patient; however, whether behavior of family members changes or not is unknown. To end this we evaluated lung cancer patients.Forty-one questions were used to collect data from patients who had been them for at least one year, evaluate in their attitudes and behaviors related prevention.The study included 246 patients' relatives, 172 (69.9%) women 74 (30.1%) men. The median age was 46 years (range: 20-83 years). Patients together an...
Background: The primary objective of our study was to examine the clinical outcomes and prognosis patients with metastatic renal cell carcinoma (mRCC) brain metastases (BMs) receiving targeted therapy. Patients methods: Fifty-eight from 16 oncology centers for whom complete data were available retrospectively reviewed. Results: median age 57 years (range 30-80). Most underwent a nephrectomy (n = 41; 70.7%), male 42; 72.4%) had clear-cell (CC) RCC 51; 87.9%). treated first-line suni-tinib 45;...
Surgical excision constitutes an important part of the treatment local advanced malignant melanoma. Due to high recurrence risk, adjuvant high-dose interferon therapy is still only used in stage IIB and III high-risk melanoma patients.One hundred two patients who received interferon-α-2b were evaluated retrospectively. The clinicopathological features, survival times, prognostic factors determined.The median disease-free overall times 25.2 60.8 months, respectively. Our findings revealed...
Background: Changes in the attitudes and behavior of relatives breast cancer patients concerning prevention screening after diagnosis a loved one were evaluated. Materials Methods: Forty-three questions used to collect data from who had been living with their for at least year. Results: The study group was composed 171 female (median age: 43, range: 17-82 yr). After diagnosed cancer, changes toward evident 78 (45.6%) participants (e.g. eating habits, quit or reduced smoking, exercise...
For HER2 positive metastatic breast cancer (MBC), continuing anti-HER2 therapy beyond progression is associated with improved outcome. However retreatment trastuzumab after lapatinib controversial. We retrospectively analyzed the efficacy of trastuzumab-based chemotherapy in HER2+ patients whose disease progressed lapatinib.Between October 2010 and May 2013, 54 were retreated chemotherapy. Efficacy toxicity results evaluated retrospectively.The median age was 46 (range 27-67). Fourteen (26%)...
The most common age at which gastric cancer is diagnosed 70 years, and the majority of patients are metastatic stage. However, although a geriatric disease, there no suggestion to discriminate treatment for general patient population. Here, we evaluated receiving palliative chemotherapy owing advanced age.Multicenter data because were retrospectively reviewed.In total, 262 with included in study. Of these, 167 patients, including 134 (51.8%) metastasis diagnosis 33 relapse after surgery,...
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