A5072296591- Renal cell carcinoma treatment
- Inflammatory Biomarkers in Disease Prognosis
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Diagnosis and Treatment
- Bone and Joint Diseases
- Cancer, Lipids, and Metabolism
- Pleural and Pulmonary Diseases
- Colorectal Cancer Surgical Treatments
- Occupational and environmental lung diseases
- Multiple and Secondary Primary Cancers
- Metastasis and carcinoma case studies
- Advanced Breast Cancer Therapies
- Radiomics and Machine Learning in Medical Imaging
- Renal and related cancers
- Lung Cancer Research Studies
- COVID-19 and healthcare impacts
- Colorectal and Anal Carcinomas
- Garlic and Onion Studies
- Adrenal and Paraganglionic Tumors
- Venous Thromboembolism Diagnosis and Management
- Soft tissue tumor case studies
- Cancer Genomics and Diagnostics
- Diagnosis and treatment of tuberculosis
- Frailty in Older Adults
Aksaray University
2025
Memorial Ankara Hospital
2023-2024
Sağlık Bilimleri Üniversitesi
2023
Universidad CES
2023
Dicle University
2015-2017
Central nervous system (CNS) metastases can be seen at a rate of 30% in advanced stages for patients with non-small cell lung cancer (NSCLC). Growing evidence indicates the predictive roles driver gene mutations development brain (BM) recent years, meaning that oncogene-driven NSCLC have high incidence BM diagnosis. Today, 3rd generation targeted drugs intracranial efficacy, which cross blood-brain barrier, made positive contribution to survival these an increased propensity BM. It is...
The hemoglobin, albumin, lymphocyte, and platelet (HALP) score, derived from a composite evaluation of markers reflecting the tumor-inflammation relationship nutritional status, has been substantiated as noteworthy prognostic determinant for diverse malignancies.To investigate how HALP score relates to prognosis in patients with metastatic gastric cancer.The cutoff values neutrophil/lymphocyte ratio, platelet/lymphocyte ratio were determined using receiver operating characteristic analysis....
Hormone positive breast cancer is a tumor with high mortality. Combining antihormonal therapy cyclin dependent kinase 4/6 inhibitors (CDK4/6i) has resulted in longer survival. The effect of inflammatory parameters such as c-reactive protein and protein/lymphocyte ratio (CLR) on efficacy survival CDK4/6i treatment unknown. In our study, we aimed to investigate the role CLR some predicting progression-free (PFS) CDK4/6i.
Aim: Breast cancer is the most common malignancy among women, with poorer survival outcomes in younger patients. Adolescents and young adults (AYAs), typically defined as women under 40–45 years, often present aggressive tumor subtypes advanced-stage disease. This study analyzes epidemiological demographic characteristics of breast patients 45 at our center to provide insights into this high-risk group. Materials Methods: retrospective analyzed 90 aged years or younger, diagnosed clinic...
Aim: This study aims to assess the clinicopathological characteristics, treatment patterns, and survival outcomes of geriatric patients with stage II-III colorectal cancer. Material Methods: retrospective included 99 (aged ≥65 years) diagnosed cancer at a single center from 2020 2024. Clinical pathological approaches, were assessed. Results: The median age diagnosis was 73 years, 63.6% male. Adjuvant chemotherapy administered 86.9% patients, significantly higher rate in III cases compared II...
The main goal of this study was to examine whether the occurrence hypothyroidism during sunitinib therapy in patients with metastatic renal cell carcinoma (mRCC) is associated a better outcome.The enrolled 81 pathologically proven mRCC who were treated between March 2008 and June 2013.Thyroid function evaluation comprised (free-thyroxine) FT4 thyroid-stimulating hormone (TSH) before treatment at day 1 each 6-week cycle. Survival analysis performed using Kaplan-Meier method, differences among...
This study investigates the prognostic significance of Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) score and Prognostic Nutritional Index (PNI) in metastatic head neck cancers. Retrospective analysis was conducted on data obtained from January 2014 to June 2022 for 68 patients using rigorous statistical methods. HALP PNI scores, derived routine laboratory parameters, were categorized into low high groups respective median values. determined through Kaplan–Meier survival analyses Cox...
Vascular endothelial growth factor (VEGF) is one of the parameters that has been studied in differential diagnosis malignant fluids. This study aimed at evaluate applicability serum, fluid VEGF level and to serum ratio pleural mesothelioma (MPM).The patients with effusion over age 18, between 2011 2015 were included study. They divided into three groups: group 1 - patients; 2 other malignancies; 3 benign aetiologies. Group termed as group. Fluid, levels, fluid/serum all groups.Twenty cases...
e15624 Background: The main goal of this study was to examine whether the occurrence hypothyroidism during sunitinib therapy in patients with metastatic renal cell carcinoma (mRCC) is associated a better outcome. Methods: enrolled81 pathologically proven mRCC who were treated between March 2008 and June 2013. Thyroid function evaluation comprised (free-thyroxine) FT4 thyroid-stimulating hormone (TSH) before treatment at day 1 each 6-week cycle. Survival analysis performed using Kaplan–Meier...
The general approach to malignant biliary obstruction (MBO) is provide drainage in all patients with jaundice. However, the procedure often palliative, and its contribution survival debated. This study aimed investigate prognostic factors undergoing percutaneous transhepatic (PTBD) for MBO.
Sarcopenia is a progressively diminishing state characterized by the reduction of muscle mass and density, which frequently observed in malignancies solid organs.
Objective: Malignant melanoma situated in the parotid gland represents a rare clinical presentation, and prognosis of these patients remains inadequately understood comparison to other forms malignant melanoma. This study aims evaluate cases gland-located under follow-up our clinic. Material Method: Records five aged 18 above, diagnosed with localized within or adjacent gland, were retrospectively reviewed. Relevant information such as patients’ demographic data including age gender, medical...
Aim: The prognostic value of platelet distribution width to lymphocyte ratio (PDWLR) in patients with metastatic renal cell cancer using tyrosine kinase inhibitors is not clearly known. Our aim this study evaluate the importance PDWLR cancer. Meterial and results: This retrospective included 66 who were currently receiving Tyrosine inhibitor treatment between January 2010 December 2020. cut off was determined by ROC curve analysis. best cut-off for RDWLR as 9.33. Sensitivity specificity...
Aim: In metastatic renal cell carcinoma (RCC), prognosis relies on various factors. Tumor lateralization's role is still debated. Our study examined how tumor localization affects survival in RCC patients.Materials and Methods: The retrospectively analyzed 80 patients with carcinoma, diagnosed between January 1999 December 2021. Results: Eighty were evaluated. median age at diagnosis was 60 (range 37-86). Tumors the right kidney for 39 (48.8%) left 41 (51.2%). Of these patients, 58 (72.5%)...
<title>Abstract</title> Background Denosumab, a RANK-ligand inhibitor, is an effectivetreatmentforfor bone metastasesfromsolidtumors.Unlikethebisphosphonates, it not excretedbythekidney. Little known, however, aboutitsefficacyandsafety in patientswith severe chronickidneydisease (CKD). Methods This study retrospective observational and was conducted as multicenter within the scope of Turkish Oncology Group (TOG) project. Patients with breast, prostate lung cancer who received denosumab...
e20086 Background: VEGF is one of the parameters that has been studied in differential diagnosis malign fluids. This study aimed to evaluate applicability serum, fluid level and serum ratio MPM. Methods: The patients with pleural effusion over age 18, between period 2011 2015 were included study. They separated into three groups: group 1: mesothelioma patients, 2: other malignancies 3: benign etiologies. Group 1 2 accepted as group. For fluid/serum In all groups, fluid, levels studied....
Amaç
 Lokal ileri rektum kanserlerinde neoadjuvan kemoradyoterapi(NAKRT) standart hale gelmiş olup patolojik tam yanıt (pCR) alınan hastalarda cerrahi yapılmadan izlem seçeneği tartışılmaktadır. Bu çalışmada NAKRT’ye yanıtı predikte edecek faktörleri araştırmayı amaçladık.
 Materyal ve metod
 2011-2021 yılları arasındaki 18 yaş üstü kanseri tanılı 184 hasta retrospektif olarak tarandı. Histopatolojik olduğu konfirme edilen lokal evre tedavi alan 79 mevcuttu. çalışma dışı...
Objective: To determine the comparative efficacy of taxane-based treatment and 5-FU-based as second-line chemotherapy regimens in advanced gastric cancer patients, measured by overall survival (OS) progression-free (PFS).
Objective: To determine the comparative efficacy of taxane-based treatment and 5-FU-based as second-line chemotherapy regimens in advanced gastric cancer patients, measured by overall survival (OS) progression-free (PFS).