A5080521312- Advanced Breast Cancer Therapies
- Nutrition and Health in Aging
- Gastric Cancer Management and Outcomes
- Coding theory and cryptography
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Esophageal Cancer Research and Treatment
- Cancer survivorship and care
- COVID-19 and healthcare impacts
- Hepatocellular Carcinoma Treatment and Prognosis
- Frailty in Older Adults
- Breast Cancer Treatment Studies
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Thyroid Disorders and Treatments
- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- Genetics, Bioinformatics, and Biomedical Research
- Vaccine Coverage and Hesitancy
- Bladder and Urothelial Cancer Treatments
- Oral health in cancer treatment
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Diabetes and associated disorders
Bezmiâlem Vakıf Üniversitesi
2021-2025
Geriatric syndromes may be more common in older cancer patients than those without cancer. can cause poor clinical outcomes. The Eastern Cooperative Oncology Group Performance Status (ECOG-PS) is often used as a clinically reported functional status score oncology practice.
Central nervous system (CNS) metastases can be seen at a rate of 30% in advanced stages for patients with non-small cell lung cancer (NSCLC). Growing evidence indicates the predictive roles driver gene mutations development brain (BM) recent years, meaning that oncogene-driven NSCLC have high incidence BM diagnosis. Today, 3rd generation targeted drugs intracranial efficacy, which cross blood-brain barrier, made positive contribution to survival these an increased propensity BM. It is...
708 Background: This study evaluates the real-world efficacy and safety of avelumab maintenance therapy in metastatic urothelial carcinoma (mUC) patients who have not progressed following first-line platinum chemotherapy, using data from EAP. Methods: The primary endpoint was overall survival (OS), progression-free (PFS) secondary endpoints included safety. PFS OS were estimated by Kaplan-Meier method. Results: One hundred seventeen received at least one cycle Avelumab. median number...
Aim: To assess the anxiety levels of breast cancer patients during COVID-19 pandemic. Materials & methods: A total 298 completed State-Trait Anxiety Inventory (STAI-S and STAI-T) Visual Analogue Scale for (VAS) VAS in (VAS-CoV). Results: 144 were high category STAI-S, 202 STAI-T. STAI-T score was significantly metastatic group (p = 0.017). VAS-CoV hormonotherapy higher than no-treatment 0.023). There a positive correlation between (r 0.708, p < 0.001), STAI-S scores 0.402, 0.001; r 0.185,...
The aim of the study was to evaluate real-world clinical outcomes atezolizumab and bevacizumab (Atez/Bev) as initial therapy for advanced hepatocellular carcinoma (HCC). We retrospectively analyzed 65 patients treated with Atez/Bev HCC from 22 institutions in Turkey between September 2020 March 2023. Responses were evaluated by RECIST v1.1 criteria. median progression-free survival (PFS) overall (OS) calculated using Kaplan–Meier method. Cox regression model employed conduct multivariate...
Although vaccination is efficacious and prevents infection in the general population, there limited data about Coronavirus disease-19 (Covid-19) occurrence after cancer patients. It was aimed to evaluate efficacy of BNT162b2 (Pfizer-BioNTech) CoronaVac vaccines against Covid-19 patients with cancer. In this single-center, retrospective, cross-sectional, descriptive study, referred medical oncology clinic a university hospital were analyzed. The sample study consisted who had or vaccinated...
Abstract Objective We aimed to evaluate cardiac safety profile of ribociclib with 24-h rhythm Holter ECG. Material and method Forty-two female metastatic breast cancer patients were included in the study. Rhythm ECG was performed before starting treatment after 3 months initiation. Results The mean age 56.36 ± 12.73. 52.4% ( n = 22) using combination fulvestrant 47.6% 20) aromatase inhibitors. None developed cardiotoxicity. When results third month compared, there no statistically...
Aim: To evaluate the relationship between anxiety and skeletal muscle index (SMI) levels in lung cancer patients on first day of chemotherapy. Materials & methods: This cross-sectional study included 108 patients. We analyzed patient characteristics, SMI levels, pain status predicted factors. Results: Anxiety was detected 61% were significantly lower high group than low (p < 0.001). A significant correlation observed (r = -0.292; p 0.002). correlated with trait 0.618; 0.001) visual analog...
Abstract Objective We aimed to evaluate cardiac safety profile of ribociclib with 24-hour-rhythm holter ECG. Material-Method: 42 female metastatic breast cancer patients were included in the study. Rhythm ECG was performed before starting treatment and after 3 months initiation. Results The mean age 56.36 ± 12.73. 52.4%(n = 22) using combination fulvestrant 47.6% (n 20) aromatase inhibitors.None developed cardiotoxicity. When rhythm results third month compared, there no statistically...
Abstract Background Neoadjuvant treatment is the standard in locally advanced ESCC. However, optimal chemotherapy regimen not known. Method This a retrospective observational cohort study conducted with propensity score matching. Patients resectable ESCC from 13 tertiary centers Türkiye were screened between January 2011 and December 2021. We compared efficacy safety of neoadjuvant chemoradiotherapy CF CROSS regimens patients Results Three hundred sixty‐two screened. who received induction (...
<title>Abstract</title> <bold>Objective</bold> We aim to determine the efficacy, and factors associated with effectiveness of first-line CDK4/6i (ribociclib or palbociclib) in HR-positive, HER2-negative MBC patients. <bold>Material method</bold> This is a retrospective, cross-sectional, descriptive study. Ninety patients metastatic breast cancer receiving CDK 4/6i from three different oncology clinics were included <bold>Results</bold> Of patients, 56 (62.2%) had received ribociclib, 34...
Objective: Hashimoto's thyroiditis, also known as chronic lymphocytic is the most common autoimmune thyroid disease in children and adolescents.The exact mechanism that triggers autoimmunity thyroiditis not fully known.Many pathologies, including disruption of intestinal epithelial barrier causes production an inappropriate immune response by interaction submucosal cells with antigens, have been accused.Zonulin a protein modulates permeability tight junctions between mucosal cells.Abnormal...