A5001201331- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Cancer Genomics and Diagnostics
- Cancer Treatment and Pharmacology
- Estrogen and related hormone effects
- Metastasis and carcinoma case studies
- Uterine Myomas and Treatments
- Chronic Lymphocytic Leukemia Research
- Genetics, Bioinformatics, and Biomedical Research
- Autoimmune Bullous Skin Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Multiple and Secondary Primary Cancers
- Gastric Cancer Management and Outcomes
- Adrenal and Paraganglionic Tumors
- Complementary and Alternative Medicine Studies
- Platelet Disorders and Treatments
- Advanced Breast Cancer Therapies
- COVID-19 and healthcare impacts
- Biomedical Text Mining and Ontologies
- Pediatric Hepatobiliary Diseases and Treatments
- HER2/EGFR in Cancer Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heavy Metal Exposure and Toxicity
- Nicotinic Acetylcholine Receptors Study
Bilkent University
2024-2025
Ankara Bilkent City Hospital
2024-2025
Memorial Ankara Hospital
2024-2025
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2018-2025
Ankara Yıldırım Beyazıt University
2022-2024
Sağlık Bilimleri Üniversitesi
2021
To compare the seropositivity rate of cancer patients with noncancer controls after inactive SARS-CoV-2 vaccination and evaluate factors affecting seropositivity.
The only phase 3 study on the effectiveness of CDK 4-6 inhibitors in first-line treatment premenopausal patients with hormone receptor (HR) positive, HER2 negative metastatic breast cancer is MONALEESA-7 study, and data palbociclib limited. Data are also limited regarding whose dose was reduced due to neutropenia, most common side effect inhibitors. In our we aimed evaluate ribociclib reduction neutropenia progression-free survival. Our a multicenter, retrospective factors affecting survival...
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but are associated with immune-related adverse events (irAEs). Pembrolizumab, an anti-PD-1 antibody, is widely used in non-small cell lung (NSCLC), yet immune thrombocytopenia remains a rare potentially fatal complication. We report case of 55-year-old male metastatic NSCLC who developed pembrolizumab-associated thrombocytopenia. The patient initially responded well to combination therapy pembrolizumab, carboplatin, and...
Introduction: Biliary tract cancers (BTC) comprise a heterogeneous group of malignancies, including gallbladder cancer, intrahepatic cholangiocarcinoma, and extrahepatic cholangiocarcinoma. The main determinants prognosis in BTC are the stage disease eligibility for curative treatment. Additionally, liver functional capacity is also one factors influencing survival biliary cancers. age–bilirubin–INR–creatinine (ABIC) score has been previously shown to predict hepatic diseases. aim our study...
In recent years, significant success has been achieved in the treatment of metastatic melanoma with use immune checkpoint inhibitors (ICIs), and it resulted a remarkable increase patient survival. However, there are only few studies reflecting daily practice outside clinical trials. The present study aimed to evaluate effectiveness safety ICI therapy Turkish patients melanoma, including those poor prognostic factors such as advanced age brain metastasis. A retrospective analysis was...
Introduction Letrozole is an aromatase inhibitor (AI), which suppresses plasma estrogen levels by inhibiting the enzyme, that causes conversion of androgens to in peripheral tissues. There very few information literature regarding development acute heart failure after AI use. We would like report a case patient who was started letrozole for hormonal treatment and developed due this. Case Fifty-seven-year-old woman with hormone positive breast cancer operated neoadjuvant chemotherapy received...
We present a patient with uncommon metastases of lung cancer. The has been followed-up for early stage laryngeal carcinoma in the remission and had dyspeptic complaints as well. A 62-year-old male epigastric three months. In upper endoscopy, biopsy specimen taken from polyp second region duodenum was reported squamous cell Immunohistochemical staining tumor cells were positive CK5/6, p40, p63. mass right detected on thorax tomography. result transthoracic needle indicated Duodenal metastasis...
Non-clear cell renal carcinoma (non-ccRCC) is a highly heterogeneous disease group, accounting for approximately 25% of all RCC cases. Due to its rarity and especially heterogeneity, phase III trial data limited treatment options generally follow those clear RCC. In the literature, there exists number studies with sunitinib, cabozantinib, everolimus, but on efficacy pazopanib are limited. Our aim in this study was compare multicenter retrospective cohort non-ccRCC patients. included patients...
Background Triple negative breast cancer (TNBC) is characterized by high rates of recurrence, especially in patients with residual disease after neoadjuvant chemotherapy (NAC). Capecitabine being used as standard adjuvant treatment TNBC. We aimed to investigate the real-life data regarding efficacy capecitabine
Aim: The prognostic value of platelet distribution width to lymphocyte ratio (PDWLR) in patients with metastatic renal cell cancer using tyrosine kinase inhibitors is not clearly known. Our aim this study evaluate the importance PDWLR cancer. Meterial and results: This retrospective included 66 who were currently receiving Tyrosine inhibitor treatment between January 2010 December 2020. cut off was determined by ROC curve analysis. best cut-off for RDWLR as 9.33. Sensitivity specificity...
Aim: In metastatic renal cell carcinoma (RCC), prognosis relies on various factors. Tumor lateralization's role is still debated. Our study examined how tumor localization affects survival in RCC patients.Materials and Methods: The retrospectively analyzed 80 patients with carcinoma, diagnosed between January 1999 December 2021. Results: Eighty were evaluated. median age at diagnosis was 60 (range 37-86). Tumors the right kidney for 39 (48.8%) left 41 (51.2%). Of these patients, 58 (72.5%)...
Non-clear cell renal carcinoma (non-ccRCC) is a highly heterogeneous disease group, accounting for approximately 25% of all RCC cases. Due to its rarity and especially heterogeneity, phase III trial data limited treatment options generally follow those clear RCC. In the literature, there exists number studies with sunitinib, cabozantinib, everolimus, but on efficacy pazopanib are limited. Our aim in this study was compare multicenter retrospective cohort non-ccRCC patients. included patients...
Introduction: Endometrium cancer is the most common gynaecological malignancy in developed countries. In this study, we aimed to investigate effect of HER2 positivity on prognosis endometrial cancer. Methods: our patients admitted clinic with a diagnosis between September 2019 and December 2023 were retrospectively evaluated. Human epidermal growth factor receptor 2 (HER2) immunohistochemistry was performed 121 patients. HER2-low group (HER2 score: 0 1) HER2-high 3) defined according score...
ÖZET GİRİŞ ve AMAÇ: Günümüzde kanser tedavisinde modern tıptaki gelişmelere rağmen tamamlayıcı alterntif tedavi (TAT) yöntemlerine olan ilgi devam etmektedir.Çalışmamızın amacı kemoterapi tedavisi alan hastalarda TAT kullanım oranlarını, çeşitlerini buna etki eden faktörlerin tespit
Böbrek, çeşitli sekresyon, reabsorpsiyon metabolik ve endokrin fonksiyonların düzenlenmesinde kontrolünde önemli bir rol oynayan, yapısal işlevsel