About
Contact & Profiles
A5065043966
Research Areas
- Epigenetics and DNA Methylation
- DNA Repair Mechanisms
- Genetics, Aging, and Longevity in Model Organisms
- Neuroscience and Neural Engineering
- Neuroscience and Neuropharmacology Research
- Ion channel regulation and function
- Insect Resistance and Genetics
Broad Institute
2022
Indiana University Bloomington
2020
10.1016/j.ibmb.2020.103493
article
EN
Insect Biochemistry and Molecular Biology
2020-11-03
T-type voltage-gated Ca
10.1021/acsptsci.1c00233
article
EN
cc-by-nc-nd
ACS Pharmacology & Translational Science
2022-02-25
ABSTRACT The oncometabolite L-2-hydroxyglutarate (L-2HG) is considered an abnormal product of central carbon metabolism that capable disrupting chromatin architecture, mitochondrial metabolism, and cellular differentiation. Under most circumstances, mammalian tissues readily dispose this compound, as aberrant L-2HG accumulation induces neurometabolic disorders promotes renal cell carcinomas. Intriguingly, Drosophila melanogaster larvae were recently found to accumulate high levels under...
10.1101/2020.05.05.078857
preprint
EN
cc-by
bioRxiv (Cold Spring Harbor Laboratory)
2020-05-06
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