A5003045660- Marine Biology and Ecology Research
- Marine Bivalve and Aquaculture Studies
- Magnetic confinement fusion research
- Ocean Acidification Effects and Responses
- Superconducting Materials and Applications
- Ionosphere and magnetosphere dynamics
- Particle accelerators and beam dynamics
- Parasite Biology and Host Interactions
- Advanced Condensed Matter Physics
- Magnetic and transport properties of perovskites and related materials
- Nematode management and characterization studies
- CRISPR and Genetic Engineering
- Iron-based superconductors research
- Advanced Nanomaterials in Catalysis
- Aquatic Invertebrate Ecology and Behavior
- Rare-earth and actinide compounds
- Ichthyology and Marine Biology
- Mollusks and Parasites Studies
- Electronic and Structural Properties of Oxides
- Marine and fisheries research
- Electrochemical sensors and biosensors
- Tracheal and airway disorders
- Crystal Structures and Properties
- Genomics and Phylogenetic Studies
- Marine and coastal plant biology
Chinese Academy of Sciences
2016-2025
Xiangtan University
2025
Yantai Institute of Coastal Zone Research
2025
Heilongjiang University
2025
Fudan University
2022-2025
Qilu Hospital of Shandong University
2020-2025
Zhejiang University
2025
Institute of Oceanology
2014-2024
Beijing National Laboratory for Molecular Sciences
2024
Beijing Institute of Petrochemical Technology
2024
During an investigation carried out by the Institute of Oceanology, Chinese Academy Sciences (IOCAS), three living raphitomid specimens were collected from a hydrothermal vent site in Manus Back-Arc Basin. Observations shell, external anatomy and radular morphology reveal that they represent undescribed species genus Phymorhynchus Dall, 1908. In this paper, we describe illustrate as oculatus sp. nov. The new is most similar general shell shape to buccinoides Okutani, Fujikura & Sasaki,...
Increasing discoveries of new species the genus Melanochlamys Cheeseman, 1881 in recent years indicate that biodiversity this group remains underestimated. Recently, several aglajid sea slugs were collected from Laizhou Bay, Shandong Province, China. Morphological observation their external and internal anatomy revealed they represent an undescribed Melanochlamys. This species, aquilina sp. nov., is closely related to fukudai Cooke, Hanson, Hirano, Ornelas-Gatdula, Gosliner, Chernyshev &...
Although miniature CRISPR-Cas12f systems were recently developed, the editing efficacy and targeting range of derived cytosine adenine base editors (miniCBEs miniABEs) have not been comprehensively addressed. Moreover, functional miniCBEs yet be established. Here we generate various Cas12f-derived miniABEs with improved activities diversified scopes. We reveal that generated traditional cytidine deaminases exhibit wide windows high off-targeting effects. To improve signatures classical CBEs...
Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder affecting women of childbearing age, and we aimed to reveal its underlying molecular mechanisms. Gene expression profiles from GSE138518 GSE155489, single-cell RNA sequencing (scRNA-seq) data PRJNA600740 were collected subjected bioinformatics analysis identify the mechanisms PCOS. The genes was detected by RT-qPCR. Through differential analysis, identified 230 common differentially expressed (DEGs) in GSE155489. GSEA results...
A new cocculinid species collected from a dolphin skull in the East China Sea is described and assigned to genus Cocculina Dall, 1882. This species, delphinicula sp. nov., has medium sized, depressed shell sculptured with regularly spaced concentric growth lines fine radial threads. The radula formula of (ca. 20)+5+1+5+(ca. 20) vestigial rachidian, lateral 1 weak but well defined, having an outline that frequently terminates into small beak-like cusp, laterals 2 3 3–4 cusps, 4 large primary...
During research dives by the submersible ROV Faxian, two margaritid species were collected in Okinawa Trough and Manus Back-Arc Basin. In present study, we describe illustrate them as Margarites similis sp. nov. manusensis nov., respectively. The generic allocation is based on shell morphology radula features. Phylogenetic reconstruction using cytochrome c oxidase subunit I (COI) gene also supports their placements within Margarites.
During an investigation carried out by the Institute of Oceanology, Chinese Academy Sciences (IOCAS), two living buccinid specimens were collected from a deep-sea methane seep area in South China Sea. Observations shell, gross anatomy and radular morphology reveal that they represent undescribed species genus Enigmaticolus. In this paper, we describe illustrate as Enigmaticolus inflatus sp. nov. The new is general shell shape most similar to marshalli Fraussen & Stahlschmidt, 2016...
Abstract Cytidine and adenosine deaminases are required for cytosine adenine editing of base editors respectively, no single deaminase could enable concurrent comparable editing. Additionally, distinct properties cytidine lead to various types off-target effects, including Cas9-indendepent DNA effects (CBEs) RNA particularly severe (ABEs). Here we demonstrate that 25 TadA orthologs be engineered generate functional ABEs, CBEs or ACBEs via double mutations, which display minimized...
Turbulence in the pedestal region of EAST tokamak has been observed and studied using reflectometry. In lower hybrid wave (LHW) or neutral beam injection (NBI) dominated heating plasma, a coherent mode (CM) was usually ELM-free phase just after L-H transition. The CM rotated electron diamagnetic drift (EDD) direction laboratory frame with poloidal number (kθ) 0.5 cm−1–0.7 cm−1 its frequency chirped from 80 – 100 kHz down to 40 50 as evolved. appearance this reduced increasing rate pressure,...
By analyzing large quantities of discharges in the unfavorable ion B ×∇B drift direction, I-mode operation has been confirmed EAST tokamak.During L-mode to transition, energy confinement a prominent improvement by formation high-temperature edge pedestal, while particle remains almost identical that L-mode.Similar with observation on other devices, E r profiles obtained eight-channel Doppler backscattering system (DBS8) [1] show deeper well than L-mode.And weak coherent mode (WCM) frequency...
A Gram-stain-negative, aerobic, motile, catalase-positive, oxidase-positive, short rod-shaped marine bacterium, designated as YIC-827 T , was isolated from Qingdao, Shandong Province, China. The results showed that cells of strain could grow optimally at 25–35 °C, pH 6.5–7.5 and 2–7% (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequence the a member genus Pseudoalteromonas . closest relative to this ruthenica KMM 300 with similarity 98.39%. digital DNA–DNA hybridization value...
P2-type Na0.5Mn0.95Ni0.05O2 as the cathode for sodium-ion batteries, has a relatively high theoretical specific capacity, but its unstable crystal structure and undesirable phase transitions lead to rapid capacity decay. In this work, Mg-B-O coated microspheres have been synthesized via liquid-phase method based on solvothermal Na0.5Mn0.95Ni0.05O2. The coating layer significantly improves electrochemical performance, including rate capability, cycle stability. Within voltage window of...
Carbon fiber-reinforced polymer (CFRP) has become widely applied in engineering fields such as aerospace and the automotive industries. Evaluating damage tolerance of CFRP with manufacturing defects under impact loads is crucial ensuring reliable service components. In this study, four types wrinkle are designed, effect mechanism thoroughly discussed, focusing on compressive response. The results indicate that primarily affect response via fibers being subjected to stress concentration....
ABSTRACT Introduction/Aims Reports on imaging‐based diagnosis of intraneural perineurioma remain limited. This study aimed to summarize the role ultrasound in diagnosing perineuriomas enhance clinical awareness and diagnostic accuracy among clinicians ultrasonographers. Methods A retrospective was conducted 11 patients diagnosed with through surgery or biopsy at our hospital between June 2015 2022. All underwent ultrasonography, their ultrasonographic characteristics were analyzed. Results...
Innate escape behaviors, while not requiring prior learning, are shaped by an animal's learned experiences, such as previous exposure. Here, we found that threat experience in mice enhances flight which is linked to increased activation of cholecystokinin-expressing neurons the dorsal premammillary nucleus (PMdCCK neurons), a population controls circa-strike responses. This heightened activity coincides with reduced inhibition from parvalbumin-expressing GABAergic ventral tegmental Gudden...
A reproducible stationary improved confinement mode (I-mode) has been achieved recently in the Experimental Advanced Superconducting Tokamak (EAST), featuring good without particle transport barrier.The microscopic mechanism of sustaining I-mode, based on coupling between turbulence transitions and edge temperature oscillation, discovered for first time.A radially localized ring oscillation (ETRO) with azimuthally symmetric structure (n = 0, m 0) identified it is accompanied by alternating...
Astrocytes are the most abundant cell type in mammalian brain and important for functions of central nervous system. Glial fibrillary acidic protein (GFAP) is regarded as a hallmark mature astrocytes, though some GFPA-positive cells may act neural stem cells. Missense heterozygous mutations GFAP cause Alexander disease that manifests leukodystrophy intellectual disability. Here, we show CUL4B, scaffold assembles E3 ubiquitin ligase, represses expression progenitor (NPCs) during development....