- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Thyroid Disorders and Treatments
- Head and Neck Anomalies
- Pituitary Gland Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Adrenal Hormones and Disorders
- Diabetes Treatment and Management
- Growth Hormone and Insulin-like Growth Factors
- Health and Wellbeing Research
- Treatment of Major Depression
- BRCA gene mutations in cancer
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Diverse Approaches in Healthcare and Education Studies
- Psychosocial Factors Impacting Youth
- Healthcare Education and Workforce Issues
- Lung Cancer Treatments and Mutations
- Regulation of Appetite and Obesity
Chonnam National University Hwasun Hospital
2014-2025
Chonnam National University
2015-2024
University of Ulsan
2024
Asan Medical Center
2024
Ulsan College
2024
Chonnam National University Hospital
2020-2024
Soonchunhyang University Hospital
2007-2021
CHA University
2014-2019
Soonchunhyang University
2006-2019
CHA Bundang Medical Center
2014-2019
As a result of various independently proposed nomenclatures and classifications, there is confusion in the diagnosis prediction biological behavior gastroenteropancreatic neuroendocrine tumors (GEP-NETs). A comprehensive nationwide study needed order to understand characteristics GEP-NETs Korea.We collected 4,951 pathology reports from 29 hospitals Korea between 2000 2009. Kaplan-Meier survival analysis was used determine prognostic significance clinicopathological parameters.Although...
Abstract Background Concern regarding the health-related quality of life (HRQOL) long-term survivors thyroid cancer has risen due to rapid increase in incidence cancer, which generally an excellent prognosis. The aim this study was evaluate status HRQOL disease-free differentiated carcinoma (DTC) and important determinants HRQOL. Methods This a cross-sectional we interviewed consecutive DTC. Three different validated questionnaires ("EORTC QLQ-C30" for various functional domains, "brief...
Background: Sorafenib and lenvatinib have been widely adopted to treat radioactive iodine (RAI)-refractory differentiated thyroid carcinoma (DTC). However, limited data exist regarding a direct comparison of these tyrosine kinase inhibitors (TKIs). We aimed evaluate the clinical efficacy safety two TKIs as first-line therapy in patients with distant metastatic or locally advanced, progressive, RAI-refractory DTC real-world practice. Methods: In this multicenter, retrospective cohort study,...
Non-thyroidal illness (NTI) refers to changes in thyroid hormone levels critically ill patients the absence of primary hypothalamic-pituitary-thyroid dysfunction, and these abnormalities usually resolve after clinical recovery. However, NTI can be accompanied by dysfunction. We report herein a case woman with hyperthyroidism.A 52-year-old female was admitted intensive care unit heart failure atrial fibrillation. She had longstanding nodule, function test revealed low triiodothyronine free...
Higher thyroid-stimulating hormone (TSH) levels are associated with differentiated thyroid cancers (DTC). To validate this association, we compared TSH obtained from euthyroid patients DTC controls in the general population.The case group included 1759 DTC, who underwent surgery at Chonnam National University Hwasun Hospital. The control (n = 1548), had participated Thyroid Disease Prevalence Study were used as a healthy group. subjects divided into four groups of similar size according to...
Thyroid immune-related adverse events (IRAEs) have been reported in patients treated with programmed cell death protein-1 (PD-1) and protein-ligand 1 (PD-L1) inhibitors. We investigated the incidence clinical course of PD-1/PD-L1 inhibitor-induced thyroid IRAEs, identified predictable risk factors particular, overt hypothyroidism (OH).We retrospectively reviewed medical records 325 cancer receiving inhibitor a tertiary referral center.A total 50.5% (164/325) experienced at least one abnormal...
Young Joo Park, Eun Kyung Lee, Shin Song, Bon Seok Koo, Hyungju Kwon, Keunyoung Kim, Mijin Bo Hyun Won Gu Bae Woong Jung-Han Hee Na, Je Moon, Jung-Eun Sohyun Jun-Ook Ji-In Bang, Kyorim Back, Youngduk Seo, Dong Yeob Shin, Su-Jin Hwa Ahn, So Oh, Seung Hoon Woo, Ho-Ryun Won, Chang Hwan Ryu, Jee Yoon, Ka Yi, Min Kyoung Sang-Woo Sihoon Ah Joon-Hyop Ji Ye Jieun Cho Rok Dong-Jun Lim, Jae-Yol Yun Jeon, Kyong Yeun Jung, Ari Chong, Jae Chung, Chan Kwon Kwanhoon Jo, Yoon Cho, A Ram Hong, Chae Moon...
Most patients with differentiated thyroid cancer (DTC) have a favorable prognosis. However, DTC and initial distant metastasis not been commonly found, their clinical characteristics seldom reported. In this study, we analyzed the features prognosis of in Korea.We retrospectively reviewed data 242 treated from 1994 to 2013, collected five tertiary hospitals Korea.The patients' median age was 51 years, 65% were women. They followed for 7 years. Lung most common site metastasis: only lung 149...
Current clinical practices favor less or no thyroid-stimulating hormone (TSH) suppression for low- to intermediate-risk thyroid cancer patients who receive lobectomy. The association of TSH on health-related quality life (HR-QoL) in after lobectomy is not well studied. This study aimed evaluate the effect patient HR-QoL
Purpose:We investigated the prognosis according to age in papillary thyroid carcinoma (PTC) patients.Methods: We retrospectively evaluated 2,890 patients who underwent thyroidectomy due PTC between May 2004 and Aug 2008.We divided into 3 groups: young (≤35 years old), middle (between 35 54 old (≥55 old).Results: Median was 47.0 (range, 15 82 years).Within a follow-up period median of 50 months, there were 148 (5.1%) locoregional recurrences, 6 (0.2%) PTC-related deaths, 18...
Background Although infrequent, distant metastasis from differentiated thyroid cancer is the main cause of mortality in patients and mostly involves lung, bone, brain. Distant metastases to other sites are rare, thus, clinical course unusual has not been adequately researched. In present study, clinico-pathological findings treatment outcomes Korea were evaluated. Patients methods We retrospectively reviewed medical records with four Korean tertiary hospitals (Chonnam National University...
The success of a low-iodine diet (LID) is best determined by measurement 24-h urine iodine (U-I) excretion. aim this study was to determine reliable estimates for U-I based on spot-urine samples and provide cut-offs the effectiveness LID preparation.We prospectively measured levels in 193 patients 24-h- before radioactive therapy. expressed as excretion (microg/day) two different indices from spot urine, simple concentration (simple I) iodine/creatinine (I/Cr) ratio. Poor preparation defined...
This study was performed to analyze the surgical pathology results of "atypia undetermined significance" (AUS) category from thyroid fine needle aspiration (FNA) and describe characteristics distinguish a malignant benign nodule.A retrospective analysis done on 116 patients who underwent surgery December 2008 2012, following diagnosis AUS preoperative FNA. We investigated age, gender, size site nodules, ultrasonographic criteria, cytological features, number atypia after repeated FNAs,...
Background: Little is known regarding disease-specific mortality of differentiated thyroid cancer (DTC) patients and its risk factors in Korea.Methods: We retrospectively reviewed a large multi-center cohort from six Korean hospitals included 8,058 DTC who underwent initial surgery between 1996 2005.Results: Mean age at diagnosis was 46.2±12.3years; 87% were females.Most had papillary (PTC; 97%) total thyroidectomy (85%).Mean size the primary tumor 1.6±1.0cm.Approximately 40% cervical lymph...
Although the introduction of novel agents improved survival outcomes in patients with multiple myeloma (MM), some died within one year (early mortality, EM) following diagnosis. In this study, we evaluated EM rate, and investigated risk factors associated MM patients. Retrospective data from 542 who were initially treated a agent-containing regimen analyzed. The median overall (OS) for entire cohort was 56.5 months. OS 2010–2014 group longer than 2002–2009 (59.2 months vs. 49.1 months, P =...
To investigate the difference in lung function according to diabetes status a community-based prospective study.
e16054 Background: Immunotherapy combined with chemotherapy is the standard palliative systemic treatment for locally advanced unresectable or metastatic gastric cancer (GC). However, patients GC and peritoneal metastases are resistant to immunotherapy. To enhance clinical benefits these patients, a comprehensive evaluation of tumor immune microenvironments (TIMEs) in metastasis malignant ascites essential. This study aimed comprehensively analyze TIME metastases. Methods: We obtained paired...