Thomas M. Klompstra

ORCID: 0000-0002-1632-0733
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About
Contact & Profiles
Research Areas
  • Neuropeptides and Animal Physiology
  • Hippo pathway signaling and YAP/TAZ
  • Cancer Cells and Metastasis
  • Pluripotent Stem Cells Research
  • Epigenetics and DNA Methylation
  • CRISPR and Genetic Engineering
  • Receptor Mechanisms and Signaling
  • Drug Transport and Resistance Mechanisms
  • Animal Genetics and Reproduction

Institute for Basic Science
2024-2025

Korea Advanced Institute of Science and Technology
2025

Karolinska Institutet
2022

Within the intestine, human G protein–coupled receptor (GPCR) GPR35 is involved in oncogenic signaling, bacterial infections, and inflammatory bowel disease. known to be expressed as two distinct isoforms that differ only length of their extracellular N-termini by 31 amino acids, but detailed insights into functional differences are lacking. Through gene expression analysis immune gastrointestinal cells, we show these emerge from promoter usage alternative splicing. Additionally, employed...

10.1016/j.jbc.2022.102328 article EN cc-by Journal of Biological Chemistry 2022-08-04

10.1016/j.ejcb.2025.151481 article EN cc-by-nc-nd European Journal of Cell Biology 2025-03-01
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