A5051923897- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Blood transfusion and management
- Cardiac Arrest and Resuscitation
- Cardiac tumors and thrombi
- Tracheal and airway disorders
- Adrenal and Paraganglionic Tumors
- Cancer, Hypoxia, and Metabolism
- Pulmonary Hypertension Research and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Cardiovascular Issues in Pregnancy
- Congenital Diaphragmatic Hernia Studies
- Mechanical Circulatory Support Devices
- Mitochondrial Function and Pathology
- Arsenic contamination and mitigation
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Effects of Exercise
- Cardiovascular and Diving-Related Complications
University of Iowa Stead Family Children’s Hospital
2020-2025
Islamic Azad University of Kermanshah
2022-2025
Islamic Azad University Kerman
2022-2025
University of Iowa
2000-2025
Imam Khomeini Hospital
2022-2024
Academic Center for Education, Culture and Research
2022-2024
University of Iowa Hospitals and Clinics
2004-2023
Karolinska University Hospital
2023
Karolinska Institutet
2023
National University of Skills
2022
Cardiac hypertrophy is considered a necessary compensatory response to sustained elevations of left ventricular (LV) wall stress.To test this, we inhibited calcineurin with cyclosporine (CsA) in the setting surgically induced pressure overload mice and examined vivo parameters volume function using echocardiography. Normalized heart mass increased 45% by 5 weeks after thoracic aortic banding (TAB; weight/body weight, 8.3+/-0.9 mg/g [mean+/-SEM] versus 5. 7+/-0.1 unbanded, P<0.05). Similar...
Abstract Pulmonary valve replacement in small children is rarely needed; when performed, it usually done surgically. Herein, we describe a hybrid technique for pulmonary through subxiphoid incision Toddler without utilising the cardiopulmonary bypass machine. The procedural thoroughly explained. Collaboration between paediatric cardiology and cardiovascular surgery teams achieved optimal outcome with minimised invasiveness.
De novo genic and copy number variants are enriched in patients with congenital heart disease, particularly those extra-cardiac anomalies. The impact of de damaging on outcomes following cardiac repair is unknown.
Background Myocyte hypertrophy accompanies many forms of heart disease, but its contribution to electrical remodeling is unknown. Methods and Results We studied mouse hearts subjected pressure overload by surgical thoracic aortic banding. In unbanded control hearts, action potential duration (APD) was significantly longer in subendocardial myocytes compared with subepicardial myocytes. Hypertrophy-associated APD prolongation greater myocytes, indicating stress-induced amplification...
Hypertrophic growth of the myocardium occurs in most forms heart failure and may contribute to pathogenesis state. Little is known about regulatory mechanisms governing often-coexisting phenotypes hypertrophy, systolic failure, diastolic stiffness that characterize clinical disease. We hypothesized intracellular signaling pathways are differentially activated by graded degrees hemodynamic stress. To test this, we developed models pressure stress mice used them directly compare compensated...
This paper presents lumped reactive capacitors and inductors to create a compact filtering hybrid ring coupler (HRC) with broad suppression band. The traditional 180-degree has six long λ/4 branches. In the proposed coupler, branches are applied instead of these branches, resulting in size reduction harmonic suppression. designed HRC works at 800 MHz provide 220 operating bandwidth from 690 910MHz, which is equal 27.5% FBW. acceptable performance frequency higher frequencies. achieves...
Tetralogy of Fallot with pulmonary atresia is a heterogeneous group defects, characterised by diverse sources flow blood to the lungs, which often include multiple systemic-to-pulmonary collateral arteries. Controversy surrounds optimal method achieve biventricular repair fewest operations while basing lungs on native intrapericardial arterial circulation whenever possible. We describe an individualized approach this patients that optimizes these variables.Over consecutive 10-year period, we...
Red blood cell transfusion is a common practice in paediatric cardiac surgery. Transfusion of red cells has been shown to be associated with an increase morbidity patients undergoing There huge variability the utilization within and across different practices. The aim this study was demonstrate current trends over past decade usage among children's hospitals performing surgery.We performed retrospective observational cohort using Paediatric Health Information System database from 43...
Trans-catheter (TC) pulmonary valve replacement (PVR) has become common practice for patients with right ventricular outflow tract obstruction (RVOTO) and/or pulmonic insufficiency (PI). Our aim was to compare PVR and (RV) function of who received TC vs surgical PVR.Retrospective review echocardiograms obtained at three time points: before, immediately after PVR, most recent.Sixty-two (median age 19 years, median follow-up 25 months) following (N = 32) or 30) Yale-New Haven Hospital were...
Background Until recently, a large right ventricle outflow tract interfered with the feasibility of standard transcatheter pulmonary valve replacement (PVR). We are describing our experience using hybrid approach for PVR left anterior thoracotomy to allow plication main artery followed by Sapien S3 valve. Methods and Results This is single-center, retrospective review patients who were evaluated be appropriate approach. The patients' demographics, procedure details, follow-up data collected....
We report a case of high-risk neonate with interrupted aortic arch (IAA) and ventricular septal defect who underwent successful hybrid palliative procedure using ductal stent bilateral branch pulmonary artery banding. This represents not only use approach in neonates IAA, but also introduces an alternative safe access for insertion through the right infundibulum.
The Harmony™ Transcatheter Pulmonary Valve (Medtronic) was recently approved by the Food and Drug Administration for transcatheter pulmonary valve replacement in native right ventricular outflow tracts. Despite this milestone, some patients have main arteries that are severely dilated continue to require surgical replacement. hybrid approach combines creation of a landing zone, deployment, suture stabilization implanted valve. In case series, we report first use Two cases reported with...
During repair of aortic coarctation, clamping the transverse arch proximal to left common carotid artery occludes blood flow and vertebral arteries. The objective present study is determine whether through right arteries provides adequate cerebral during cross-clamping, as assessed by near-infrared spectroscopy.In 11 consecutive children undergoing coarctation a standard posterolateral thoracotomy, regional oxygen saturation (cSO(2)) was measured using spectroscopy. Six patients underwent an...
In this paper, new LC lumped components and composite lines are used to create a filtering branch line coupler (FBLC) with small size wide suppression band. New proposed using applied components, which as the main branches. The FBLC suppresses second sixth harmonics high attention level provides stopband from 1.6 GHz 5 more than 20 dB of attention. presented is analyzed, designed, simulated, implemented. measured results show that correctly operates at 800 MHz less 0.25 insertion loss....