A5020034631- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Renal and Vascular Pathologies
- Hormonal and reproductive studies
- Multiple and Secondary Primary Cancers
- Renal and related cancers
- Pelvic floor disorders treatments
- Economic and Financial Impacts of Cancer
- Pancreatic and Hepatic Oncology Research
- Global Cancer Incidence and Screening
- Organ Donation and Transplantation
- Ureteral procedures and complications
- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Urologic and reproductive health conditions
- Cancer, Lipids, and Metabolism
- Renal Transplantation Outcomes and Treatments
- Sexual Differentiation and Disorders
- Cancer Diagnosis and Treatment
- Phytoestrogen effects and research
- Tea Polyphenols and Effects
University of California, San Diego
2025
University of California, Irvine Medical Center
2019-2024
VA Long Beach Healthcare System
2016-2024
University of California, Irvine
2018-2023
Indianapolis Zoo
2020
University of Richmond
2020
Albany Research Institute
2020
New York Proton Center
2015-2020
Icahn School of Medicine at Mount Sinai
2015-2018
Mount Sinai Hospital
2018
Object Decompressive craniectomy is a potentially life-saving procedure used in the treatment of medically refractory intracranial hypertension, most commonly setting trauma or cerebral infarction. Once performed, surviving patients are obligated to undergo second for cranial reconstruction. The complications following reconstruction not well described literature and may very be underreported. A review would suggest measures improve care these patients. Methods retrospective chart was...
We report 5-year safety and efficacy outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia large-volume prostate glands.A total 101 moderate to severe symptoms volumes between 80 150 mL underwent a robotic-assisted in prospective multicenter international trial (NCT03123250). Herein we final results.The study successfully met its performance goal, which was based upon transurethral resection typically done smaller prostates, at 3 months. Mean...
To present early safety and feasibility data from a multicentre prospective study (WATER II) of aquablation in the treatment symptomatic men with large-volume benign prostatic hyperplasia (BPH).Between September December 2017, 101 moderate-to-severe BPH symptoms prostate volume 80-150 mL underwent international clinical trial. Baseline demographics standardized postoperative management variables were carefully recorded central independently monitored database. Surgeons answered analogue...
To present 6-month safety and effectiveness data from a multicentre prospective study of aquablation in men with lower urinary tract symptoms (LUTS) attributable to benign prostatic hyperplasia (BPH) prostate volumes between 80 150 mL.Between September December 2017, 101 LUTSattributable BPHwere prospectively enrolled at 16 centres Canada the USA.The mean volume was 107 mL. The length hospital stay after procedure 1.6 days (range: same day 6 days). primary endpoint (Clavien-Dindo grade 2 or...
To report 12-month safety and effectiveness outcomes of the Aquablation procedure for treatment men with symptomatic benign prostatic hyperplasia (BPH) large-volume prostates.One hundred one moderate-to-severe BPH symptoms prostate volumes 80-150 cc underwent a robotic-assisted in prospective multicenter international clinical trial. Functional were assessed at 12 months postoperatively.Mean volume was 107 (range 80-150). Mean operative time 37 minutes mean resection 8 minutes. The average...
The objective of this study is to determine if Aquablation therapy can maintain its effectiveness in treating men with lower urinary tract symptoms (LUTS) due benign prostatic hyperplasia (BPH) large-volume (80-150 cc) prostates at 3 years. One hundred one moderate-to-severe BPH and prostate volumes between 80 150 cc were enrolled a prospective, nonrandomized, multicenter, international clinical trial late 2017. Baseline, procedural, follow-up parameters recorded baseline scheduled...
To report our experience with ureteroenteric anastomotic revision as initial treatment of stricture after urinary diversion.An institutional review board-approved retrospective study was carried out. A total 41 patients who underwent primary anastamotic were identified between 2007 and 2015. Data analyzed included patient characteristics, type diversion, estimated blood loss, operative time, change in renal function, length stay, postoperative complications time nephrostomy/stent. Success...
Performing partial nephrectomy (PN) on a cT1 tumor, which postoperatively is upgraded to pT3a can possibly lead compromise of cancer specific mortality. We therefore aimed identify risk factors for pathologic T3a upstaging tumors and analyze the association between upstaging, positive surgical margins (PSM) overall survival (OS).The present study included patients who underwent PN clinically localized T1 renal mass from two datasets: 1) 1298 prospectively maintained multi-center database...
The treatment paradigm for metastatic hormone-sensitive prostate cancer (mHSPC) patients is evolving. PET/CT now offers improved sensitivity and accuracy in staging. Recent randomized trial data supports escalated hormone therapy, local primary tumor metastasis-directed therapy. impact of combining such therapies into a multimodal approach unknown. This Phase II single-arm clinical sponsored funded by Veterans Affairs combines local, metastasis-directed, systemic to durably render free...
7031 Background: There are a limited number of studies that have evaluated the association between National Comprehensive Cancer Network (NCCN) guideline adherence and survival across different cancers. We aim to assess relationship race/ethnicity, socioeconomic status (SES), insurance type receipt NCCN concordant cancer care survival. Methods: This is retrospective population-based cohort study patients with 7 types invasive using California Registry. Adherence guidelines was defined by...
To assess the diagnostic performance and utility of ExoDx IntelliScore an OPKO4K score to predict prostate cancer in men presenting with elevated PSA-both as independent predictors combination clinical/MRI characteristics.
UPII-mutant Ha-ras transgenic mice develop urothelial hyperplasia and low-grade papillary carcinoma, which mimics human non-muscle invasive bladder cancer (NMIBC). We investigated the effects mechanisms of kawain, a main kavalactone in kava plant, on oncogenic Ha-ras-driven carcinoma these mice. The were fed at six weeks age with vehicle control or kawain (6 g/kg) formulated food for approximately five months. Seventy-eight percent more survived than months age, whereas only 32% food-fed...
Epidemiological evidence suggests that kava (Piper methysticum Forst) drinks may reduce the risk of cancer in South Pacific Island smokers. However, little is known about anti-carcinogenic effects on tobacco smoking-related bladder and its underlying mechanisms. Here we show dietary feeding kawain (a major active component root extracts) to mice either before or after hydroxy butyl(butyl) nitrosamine (OH-BBN) carcinogen exposure slows down urinary carcinogenesis prolongs survival...
Introduction and Objective: Robot-assisted radical nephrectomy (RRN) is increasingly utilized as an alternative to laparoscopic (LRN), but there are concerns over costs objective benefit. In the setting of very large renal masses (>10 cm), comparison between techniques limited it unclear whether a robotic approach confers any perioperative benefit LRN or open (ORN). this study, outcomes RRN, LRN, ORN for compared. Methods: Using National Cancer Database, patients were identified who...
163 Background: Treatment paradigms for oligometastatic castration-sensitive prostate cancer patients are evolving. Molecular imaging improves staging, intensified systemic and primary tumor directed therapy survival, metastasis-directed local control. The impact of combining these therapeutic approaches into a planned multimodal treatment strategy is unknown. Here we report prospective phase II single-arm trial local, metastasis-directed, therapies limited duration with the objective to...