- Advanced MRI Techniques and Applications
- NMR spectroscopy and applications
- Advanced Neuroimaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Surgical Simulation and Training
- MRI in cancer diagnosis
- Advanced NMR Techniques and Applications
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Numerical methods in inverse problems
- Electron Spin Resonance Studies
- Medical Image Segmentation Techniques
- Quantum, superfluid, helium dynamics
- Mathematical functions and polynomials
- Fractional Differential Equations Solutions
- Computer Graphics and Visualization Techniques
- Liver Disease Diagnosis and Treatment
- Anatomy and Medical Technology
- Mathematical Biology Tumor Growth
- Cellular Mechanics and Interactions
- Advanced Image Processing Techniques
- Retinal Imaging and Analysis
- Liver Disease and Transplantation
- Augmented Reality Applications
- Medical Imaging and Analysis
Karl Storz (Germany)
2023-2024
Heidelberg University
2015-2022
German Cancer Research Center
2015-2022
University Hospital Heidelberg
2017-2020
Heidelberger Institut für Radioonkologie
2017
The cylindrical Bessel differential equation and the spherical in interval [Formula: see text] with Neumann boundary conditions are considered. eigenfunctions linear combinations of function or functions text]. orthogonality relations analytical expressions for normalization constant given. Explicit Lommel integrals terms derived. cross product zeros considered complex plane real as well values index approximations exceptional zero obtained. A numerical scheme based on discretization...
Objectives To apply the MB (multiband) excitation and blipped-CAIPI (blipped-controlled aliasing in parallel imaging) techniques a spin gradient-echo (SAGE) EPI sequence to improve slice coverage for vessel architecture imaging (VAI). Materials methods Both with in-plane were incorporated into (GE)/spin-echo (SE) simultaneous tracking of dynamic MR signal changes both GE SE contrasts after injection contrast agent. singleband (SB) compared using 20-channel head coil at 3 Tesla,...
Since changes in lung microstructure are important indicators for (early stage) pathology, there is a need quantifiable information of diagnostically challenging cases clinical setting, e.g. to evaluate early emphysematous peripheral tissue. Considering alveoli as spherical air-spaces surrounded by thin film tissue allows deriving an expression Carr-Purcell-Meiboom-Gill transverse relaxation rates R2 with dependence on inter-echo time, local air-tissue volume fraction, diffusion coefficient...
We propose a surface model of spin dephasing in lung tissue that includes both susceptibility and diffusion effects to provide closed-form solution the Bloch-Torrey equation on alveolar surface. The nonlocal are validated against numerical simulations realistic geometry acquired from synchotron-based $\ensuremath{\mu}\mathrm{CT}$ data sets mouse tissue, well-known Wigner-Seitz geometry. free induction decay is obtained dependence microscopic parameters agrees very well with vivo measurements...
In biological tissue, an accumulation of similarly shaped objects with a susceptibility difference to the surrounding tissue generates local distortion external magnetic field in resonance imaging. It induces stochastic fluctuations that characteristically influence proton spin diffusion vicinity these perturbers. The correlation is associated such inhomogeneities can be expressed form dynamic frequency autocorrelation function related time evolution measured magnetization. Here,...
The Brownian motion of spins diffusing in an inhomogeneous magnetic field created by susceptibility effects is considered. Applying the correct form Gaussian approximation, method allows calculating local magnetization as well free induction decay for all diffusion regimes. phase accumulated during diffusional treated averaging over possible trajectories terms approximation. Predictions approximation are compared with a constant gradient slab, cylinder, and sphere. thereby, shows several...
Surgical instrument segmentation in laparoscopy is essential for computer-assisted surgical systems. Despite the Deep Learning progress recent years, dynamic setting of laparoscopic surgery still presents challenges precise segmentation. The nnU-Net framework excelled semantic analyzing single frames without temporal information. framework's ease use, including its ability to be automatically configured, and low expertise requirements, have made it a popular base comparisons. Optical flow...
The spin echo signal from vessels in Krogh's capillary model as well the random distribution vessel are studied by numerically solving Bloch-Torrey equation. A comparison is made with Gaussian local phase approximation, approximation and strong-collision approximation. Differences between explained. In intermediate diffusion regime, full numerical solution shows oscillations which absent any of approximate solutions. limit large coefficients, where approximations become exact, a...
Magnetic resonance imaging based on steady-state free precision (SSFP) sequences is a fast method to acquire <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow></mml:msub></mml:math>, id="M2"><mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:math>, and...