Trey Sunderland
A5050572165- Conservation, Biodiversity, and Resource Management
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Land Use and Ecosystem Services
- African Botany and Ecology Studies
- Memory and Neural Mechanisms
- Forest Management and Policy
- Economic and Environmental Valuation
- Cholinesterase and Neurodegenerative Diseases
- Ecology and Vegetation Dynamics Studies
- Agriculture, Land Use, Rural Development
- Treatment of Major Depression
- X-ray Diffraction in Crystallography
- Forest ecology and management
- Crystallization and Solubility Studies
- Agriculture and Rural Development Research
- Nicotinic Acetylcholine Receptors Study
- Stress Responses and Cortisol
- Rangeland Management and Livestock Ecology
- Oil Palm Production and Sustainability
- Neurotransmitter Receptor Influence on Behavior
- Agricultural Innovations and Practices
- Cambodian History and Society
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
University of British Columbia
2017-2025
Center for International Forestry Research
2015-2024
James Cook University
2009-2023
Natural England
2012-2022
University of Wisconsin–Madison
2015-2018
University of Nevada, Reno
2018
Okanagan University College
2018
VA Connecticut Healthcare System
2014-2017
Yale University
2014-2017
The University of Texas Southwestern Medical Center
2016-2017
The biodiversity-productivity relationship (BPR) is foundational to our understanding of the global extinction crisis and its impacts on ecosystem functioning. Understanding BPR critical for accurate valuation effective conservation biodiversity. Using ground-sourced data from 777,126 permanent plots, spanning 44 countries most terrestrial biomes, we reveal a globally consistent positive concave-down BPR, showing that continued biodiversity loss would result in an accelerating decline forest...
"Landscape approaches" seek to provide tools and concepts for allocating managing land achieve social, economic, environmental objectives in areas where agriculture, mining, other productive uses compete with biodiversity goals. Here we synthesize the current consensus on landscape approaches. This is based published literature a consensus-building process define good practice validated by survey of practitioners. We find approach has been refined response increasing societal concerns about...
We have tested a simple and reliable measure of visuospatial ability in Alzheimer patients--the Clock Drawing Test. To determine the usefulness this measure, we asked 67 patients 83 normal controls to draw face clock reading time 2:45. Six independent observers blindly evaluated results with ratings from 10 (best) 1 (worst). The mean performance score subjects was 4.9 +/- 2.7 compared 8.7 1.1 for (P less than .001). Inter-rater reliability clocks drawn by highly significant (r = 0.86; P...
<h3>Objective.</h3> —A consensus conference on the diagnosis and treatment of Alzheimer disease (AD) related disorders was organized by American Association for Geriatric Psychiatry, Alzheimer's Association, Geriatrics Society January 4 5, 1997. The target audience primary care physicians, following questions were addressed: (1) How prevalent is AD what are its risk factors? What impact society? (2) different forms dementia how can they be recognized? (3) constitutes safe effective AD?...
Neurological dysfunction, seizures and brain atrophy occur in a broad spectrum of acute chronic neurological diseases. In certain instances, over-stimulation N-methyl-D-aspartate receptors has been implicated Quinolinic acid (QUIN) is an endogenous receptor agonist synthesized from L-tryptophan via the kynurenine pathway thereby potential mediating neuronal damage dysfunction. Conversely, related metabolite, kynurenic acid, antagonist could modulate neurotoxic effects QUIN as well disrupt...
We combined two existing datasets of vegetation aboveground biomass (AGB) (Proceedings the National Academy Sciences United States America, 108, 2011, 9899; Nature Climate Change, 2, 2012, 182) into a pan-tropical AGB map at 1-km resolution using an independent reference dataset field observations and locally calibrated high-resolution maps, harmonized upscaled to 14 477 estimates. Our data fusion approach uses bias removal weighted linear averaging that incorporates spatializes patterns...
This is a reversed-phase liquid-chromatographic method, with electrochemical detection, for simultaneously measuring, in plasma, the concentrations of catecholamine precursor dihydroxyphenylalanine (DOPA); endogenous catecholamines norepinephrine, epinephrine, and dopamine; deaminated metabolites dihydroxyphenylacetic acid (DOPAC) dihydroxyphenylglycol (DHPG). We used this method to assess effects monoamine oxidase (EC 1.4.3.4) inhibition humans. Plasma DHPG as determined by present (mean...
Abstract Aim Large trees (d.b.h. ≥ 70 cm) store large amounts of biomass. Several studies suggest that may be vulnerable to changing climate, potentially leading declining forest biomass storage. Here we determine the importance for tropical storage and explore which intrinsic (species trait) extrinsic (environment) variables are associated with density at continental pan‐tropical scales. Location Pan‐tropical. Methods Aboveground ( AGB) was calculated 120 intact lowland moist locations....
Overexpression of the familial Alzheimer's disease gene Presenilin 2 ( PS2 ) in nerve growth factor-differentiated PC12 cells increased apoptosis induced by trophic factor withdrawal or β-amyloid. Transfection antisense conferred protection against amyloid precursor protein-expressing cells. The apoptotic cell death protein was sensitive to pertussis toxin, suggesting that heterotrimeric GTP-binding proteins are involved. A mutation associated with found generate a molecule enhanced basal...
We report above-ground biomass (AGB), basal area, stem density and wood mass estimates from 260 sample plots (mean size: 1.2 ha) in intact closed-canopy tropical forests across 12 African countries. Mean AGB is 395.7 Mg dry ha⁻¹ (95% CI: 14.3), substantially higher than Amazonian values, with the Congo Basin contiguous forest region attaining values (429 ha⁻¹) similar to those of Bornean forests, significantly greater East or West forests. therefore appears generally palaeo- compared...
Abstract Tropical forests are global centres of biodiversity and carbon storage. Many tropical countries aspire to protect forest fulfil climate mitigation policy targets, but the conservation strategies needed achieve these two functions depend critically on tree diversity-carbon storage relationship. Assessing this relationship is challenging due scarcity inventories where stocks in aboveground biomass species identifications have been simultaneously robustly quantified. Here, we compile a...
This paper examines the literature on how biodiversity contributes to improved and diversified diets in developing countries. We assess current state of evidence wild cultivated all forms is related healthy nutrition, examine economic factors, knowledge social norms interact with availability influence both production consumption choices. The identifies areas where lacking ways build synergies between nutrition-sensitive approaches efforts ensure sustainability food systems natural environment.
In a world where natural capital is often unpriced or undervalued, thus making resource exploitation very lucrative, environmentally degrading activities will continue to dominate the economy. The past decade has seen bourgeoning interest in scaling up private investment address persistent socioeconomic and environmental challenges globally. recently formulated sustainable development goals global climate agenda have further heightened urgency for more holistic integrated conceptualization...
The relationship between forests and human nutrition is not yet well understood. A better understanding of this vital at a time when the majority new land for agriculture being cleared from forests. We use Demographic Health Survey data on food consumption children 21 African countries Global Land Cover Facility tree cover to examine three key indicators nutritional quality children's diets: dietary diversity, fruit vegetable consumption, animal source consumption. Our main findings can be...
This study uses a multi-case dataset to question current assumptions about the gender differentiation of forest product use. We test some commonly held ideas on how men and women access, manage, use different products. Overall, we found significant in collection products, which seems support claim that there are distinctive "male" "female" roles associated with However, also play much more important diverse role contribution products rural livelihoods than previously reported, strong...
Despite expanding interest in ecosystem service research over the past three decades, in-depth understanding of contribution forests and trees to food production livelihoods remains limited. This review synthesizes current evidence base examining forest agricultural tropics, where often occurs within complex land use mosaics that are increasingly subjected concomitant climatic anthropogenic pressures. Using systematic methodology we found 74 studies investigating effect or tree-based...
• Majority forecasts for feeding the future global population predict an increase in a croplands at expense of forests and pastures. A third shows that it is feasible to halt further agricultural expansion mitigate climate change. Policy provides economic incentives carbon stock conservation enhancement only effective option reverse trend forest loss.
• Many food security experts have been calling for agricultural intensification in developing countries to feed a growing global population. This narrative is based on narrow view of focused calories and neglects issues dietary quality. Encouraging small farmers across the world grow more staple crops intensively may unintended negative consequences A nuanced approach sensitive local contexts appreciative foods other than staples lead alternative policy choices many places.