- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Attention Deficit Hyperactivity Disorder
- Neural and Behavioral Psychology Studies
- Sleep and Wakefulness Research
- Advanced Neuroimaging Techniques and Applications
- Mechanical Circulatory Support Devices
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Clinical practice guidelines implementation
- Cervical Cancer and HPV Research
- Radiomics and Machine Learning in Medical Imaging
- Diversity and Impact of Dance
- Diverse Approaches in Healthcare and Education Studies
- Simulation-Based Education in Healthcare
- Innovations in Medical Education
- Anesthesia and Neurotoxicity Research
- COVID-19 Clinical Research Studies
- Congenital Heart Disease Studies
- Interprofessional Education and Collaboration
- Sepsis Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Cardiovascular Conditions and Treatments
- Sleep and related disorders
Oxford University Hospitals NHS Trust
2023
University of Hull
2022
Liverpool John Moores University
2022
Hospital for Sick Children
2014-2019
Krembil Research Institute
2019
Toronto Western Hospital
2019
University of Toronto
2011-2017
SickKids Foundation
2016
Swansea University
2010
Children with traumatic brain injury (TBI) are frequently at risk of long-term impairments attention and executive functioning but these problems difficult to predict. Although deficits have been reported vary severity, age sex, prognostication outcome remains imperfect a patient-specific level. The objective this proof principle study was evaluate variety patient variables, along six brain-specific inflammatory serum protein biomarkers, as predictors cognitive following paediatric TBI....
Objective: To evaluate the association between acute serum biomarkers, and changes in attention at 1 year following traumatic brain injury. Design Setting: A prospective observational laboratory study conducted PICUs five Canadian children’s hospitals. Study Population Measurements: Fifty-eight patients aged 5 to 17 years with injury were enrolled study. Nine brain-specific inflammatory protein biomarkers measured multiple times over first week Attention was “baseline” represent pre-injury...
We examined systems-level costs before and after the implementation of an emergency department paediatric sepsis screening, recognition treatment pathway. Aggregated hospital admissions for all children aged < 18y with a diagnosis code upon admission in Queensland, Australia were compared 16 participating 32 non-participating hospitals pathway implementation. Monte Carlo simulation was used to generate uncertainty intervals. Policy impacts estimated using difference-in-difference analysis...
Thirty preterm infants (gestational age 26 to 30 weeks) were investigated by cross sectional echocardiography using a 5 or 7.5 MHz transducer positioned in the suprasternal notch left subclavicular position enable visualisation of aortic arch, main pulmonary artery, and ductus arteriosus. Each infant was on at least one occasion during both first second weeks life when possible between ages 31 days. There prolonged patency arteriosus two all infants, complete closure occurred only four...
One of the most commonly reported injuries in children who participate sports is concussion or mild traumatic brain injury (mTBI)1. Children and youth involved organized such as competitive hockey are nearly six times more likely to suffer a severe compared other leisure physical activities2. While common cognitive sequelae mTBI appear similar for adults, recovery profile breadth consequences remains largely unknown2, does influence pre-injury characteristics (e.g. gender) details magnitude...
The Committee wrote to all medical officers in charge of clinics Great Britain, and 94 them expressed their willingness join the activities Group.Dr. Guthe World Health Organization, who was asked suggest a line study which would contribute information value organizations concerned with international control venereal diseases, replied that effects methods intensive treatment early syphilis be most valuable.
Ensuring that pre-registration student nurses gain the richness of clinical practice to allow them feel confident and knowledgeable care for patients 21st century is often a challenge. Clinical challenges mean students will be strategic learners. This article discusses development virtual case-based learning site provide rich experience learn.
<h3>ABSTRACT</h3> <h3>Introduction</h3> Healthcare organisations have had to make adaptations reduce the impact of Coronavirus 2019 (COVID-19) pandemic. This has necessitated urgent reconfiguration within inflammatory bowel disease (IBD) services ensure safety patients and staff seamless continuity care provision. <h3>Aim</h3> To describe made by a large service, caring for over 3,500 IBD patients, in response COVID-19 <h3>Methods</h3> A diary record responses pandemic were logged, meeting...
Children with traumatic brain injury are reported to have deficits in performance monitoring, but the mechanisms underlying these not well understood. Four monitoring hypotheses were explored by comparing how 28 children and typically developing controls (matched age sex) performed on stop-signal task. Control slowed significantly more following incorrect than correct trials, fitting error hypothesis. In contrast, group showed no difference trial types, significant differences did emerge,...
Background and aims: Inattention hyperactivity problems are over-represented in children with TBI, both pre- post-injury. These attention difficulties occur across all severities of suggesting severity injury alone does not predict individual differences outcomes. Given that frontal lobe integrity is important for diffuse axonal (DAI) the lobes common after we set out to investigate whether DAI predicts following TBI. Aims: To establish trajectory TBI as rated by parents teachers, gain an...