Fatima Clouser
A5064810778- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Rabies epidemiology and control
- Corneal surgery and disorders
- Viral Infections and Vectors
- Glaucoma and retinal disorders
- Travel-related health issues
- Diabetic Foot Ulcer Assessment and Management
- Advanced Sensor and Energy Harvesting Materials
- Optical Coherence Tomography Applications
- Corneal Surgery and Treatments
- Pediatric health and respiratory diseases
- Advanced Fiber Optic Sensors
- Mosquito-borne diseases and control
- Silk-based biomaterials and applications
University of Chicago
2014-2023
Massachusetts General Hospital
2019-2021
Harvard University
2019-2021
Abstract Corneal stiffness plays a critical role in shaping the cornea with respect to intraocular pressure and physical interventions. However, it remains difficult measure mechanical properties noninvasively. Here, we report first measurement of shear modulus human corneas vivo using optical coherence elastography (OCE) based on surface elastic waves. In pilot study 12 healthy subjects aged between 25 67, Rayleigh-wave speed was 7.86 ± 0.75 m/s, corresponding 72 14 kPa. Our data reveal two...
Toxoplasma gondii infection causes substantial morbidity and mortality in the United States, infects approximately one-third of persons globally. Clinical manifestations vary. Seropositivity is associated with neurologic diseases malignancies. There are few objective data concerning US incidence distribution toxoplasmosis.
Background Congenital toxoplasmosis is a serious but preventable and treatable disease. Gestational screening facilitates early detection treatment of primary acquisition. Thus, fetal infection can be promptly diagnosed treated outcomes improved. Methods We tested 180 sera with the Toxoplasma ICT IgG-IgM point-of-care (POC) test. Sera were from 116 chronically infected persons (48 serotype II; 14 I-III; 25 I-IIIa; 28 Atypical, haplogroup 12; 1 not typed). These represent strains parasites...
Abstract Optical fibers made of thermoset elastomeric materials can offer extremely high stretchability not possible with conventional glass and plastic optical fibers. However, such elastomer have so far been large mm‐scale diameters, which limit their potential utilities. Here, fabrication small‐diameter (< 200 µm), core‐clad using a thermal drawing transparent thermoplastic elastomers is demonstrated. The single‐mode fabricated by this method are highly elastic durable against strain...
Background Congenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, substantial costs worldwide. Objectives We asked whether high performance an Immunochromatographic-test (ICT) could enable accurate, rapid diagnosis/treatment, establishing new, improved care-paradigms at point-of-care clinical laboratory. Methods Data were obtained in 12 studies/analyses addressing: 1-feasibility/efficacy;...
Abstract Purpose of Review work to create and evaluate educational materials that could serve as a primary prevention strategy help both providers patients in Panama, Colombia, the USA reduce disease burden Toxoplasma infections. Recent Findings Educational programs had not been evaluated for efficacy USA, or Colombia. Summary high school students, pregnant women, medical students professionals, scientists, lay personnel were created. In most settings, short-term effects evaluated. all...
Abstract Background Congenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, substantial costs worldwide. Methods/Findings In our ongoing USA feasibility/efficacy clinical trial, data collated with other earlier published results proved high performance an Immunochromatographic-test(ICT) that enables accurate, rapid diagnosis/treatment, establishing new paradigms for care. Overall from patient blood...
Purpose: To investigate the feasibility of using Brillouin microscopy for assessment corneal edema in patients with Fuchs endothelial dystrophy (FECD). analyzes frequency shift light inelastically scattered by naturally occurring acoustic waves a small volume tissue. The resulting is measure local hydromechanical properties Methods: Participants were scanned clinical imaging system (780 nm laser, 5 mW), and color-coded map mean laterally across stroma was created. Results: maps normal...
Review comprehensive data on rates of toxoplasmosis in Panama and Colombia.Samples sets from Colombia, that facilitated estimates regarding seroprevalence antibodies to Toxoplasma risk factors, were reviewed.Screening maps, factor mathematical models devised based these data. Studies Ciudad de Panamá estimated at between 22 44%. Consistent relationships found higher prevalence factors such as poverty proximity water sources. Prenatal screening for anti-Toxoplasma variable, despite existence...