- Viral Infections and Outbreaks Research
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Advanced Radiotherapy Techniques
- Angiogenesis and VEGF in Cancer
- Ubiquitin and proteasome pathways
- Protease and Inhibitor Mechanisms
- Mesenchymal stem cell research
- Zebrafish Biomedical Research Applications
- Marine Biology and Ecology Research
- S100 Proteins and Annexins
- Adipose Tissue and Metabolism
- Cancer Research and Treatments
- Peptidase Inhibition and Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Inflammasome and immune disorders
- Metabolism, Diabetes, and Cancer
- COVID-19 Clinical Research Studies
- Mitochondrial Function and Pathology
- Protist diversity and phylogeny
- Cancer, Hypoxia, and Metabolism
- COVID-19 epidemiological studies
- Advances in Oncology and Radiotherapy
- Antibiotic Resistance in Bacteria
Mianyang Third People's Hospital
2022
Chengdu Third People's Hospital
2022
Chinese PLA General Hospital
2020-2021
National Institute for Communicable Disease Control and Prevention
2010-2021
National Vaccine and Serum Institute
2021
China Association for Science and Technology
2021
The Military General Hospital of Beijing PLA
2014
302 Military Hospital of China
2010
Cefiderocol has been approved in the United States and Europe but not China. We aim to evaluate carbapenem-resistant Enterobacterales (CRE) susceptibility cefiderocol provide baseline data investigate resistance mechanism. From 2018 2019, 1,158 CRE isolates were collected from 23 provinces municipalities across The MICs of antimicrobials determined via agar dilution broth microdilution methods. Whole-genome sequencing was performed for 26 cefiderocol-resistant Escherichia coli Clone...
Norovirus (NoV) is the major pathogen causing outbreaks of viral gastroenteritis across world. Among various genotypes NoV, GII.4 most predominant over past decades. NoVs interact with histo-blood group antigens (HBGAs) to invade host cell, and it believed that receptor HBGAs may play important roles in selecting predominate variants by nature during evolution NoVs. However, evolution-induced changes HBGA-binding affinity for NoV mechanism behind NoV-HBGA interactions remain elusive. In...
Hematopoietic stem cells (HSCs) are derived from hemogenic endothelial (HECs) during embryogenesis. The HSC-primed HECs increased to the peak at embryonic day (E) 10 and have been efficiently captured by marker combination CD41 – CD43 CD45 CD31 + CD201 Kit CD44 (PK44) in aorta-gonad-mesonephros (AGM) region of mouse embryos most recently. In present study, we investigated spatiotemporal functional heterogeneity PK44 around time emergence HSCs. First, E10.0 AGM could be further divided into...
Intensity-modulated radiotherapy (IMRT) potentially leads to a more favorite dose distribution compared 3-dimensional or conventional tangential (RT) for breast cancer after conservative surgery mastectomy. The aim of this study was compare dosimetric parameters the planning target volume (PTV) and organs at risk (OARs) among helical tomotherapy (HT), inverse-planned IMRT (IP-IMRT), forward-planned field in (FP-FIF) techniques breast-conserving surgery. Computed tomography scans from 20...
Abstract Background: The development of severe coronavirus disease 2019 (COVID-19) is associated with systemic hyperinflammation, which drives multi-organ failure and death. Disease deterioration tends to occur when the virus receding; however, whether other factors besides viral products are involved in inflammatory cascade remains unclear. Methods: Twenty-eight COVID-19 patients laboratory-confirmed SARS-CoV-2 infection hospitalized at Fifth Medical Center Chinese PLA General Hospital from...
Objective To isolate and identify the causative agent in an incident with crowd fever of adults Henan province.Methods The cells was inoculated by throat swabs patients followed neutralization assay other molecular methods.Then indirect immunofluorescence performed to detect specific IgM/IgG antibodies against virus serum patients.Results We have isolated 2 strain adenoviruses from 10 swab samples,which were both identified as Ad11 sequence analysis test.6 samples positive fer IgM for...