A5042779285- Functional Brain Connectivity Studies
- Eating Disorders and Behaviors
- Advanced Neuroimaging Techniques and Applications
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Autism Spectrum Disorder Research
- Treatment of Major Depression
- Electroconvulsive Therapy Studies
- Schizophrenia research and treatment
- Transcranial Magnetic Stimulation Studies
- Attention Deficit Hyperactivity Disorder
- Neural and Behavioral Psychology Studies
- Child and Adolescent Psychosocial and Emotional Development
- Advanced MRI Techniques and Applications
- COVID-19 and Mental Health
- Psychosomatic Disorders and Their Treatments
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Child Nutrition and Feeding Issues
- Health, Environment, Cognitive Aging
- Bipolar Disorder and Treatment
- Genetics and Neurodevelopmental Disorders
- Long-Term Effects of COVID-19
- Neuroendocrine regulation and behavior
Hospital Sant Joan de Déu Barcelona
2019-2024
Institut de Recerca Sant Joan de Déu
2020-2024
Sant Joan de Déu Research Foundation
2023-2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2020-2023
Parc Sanitari Sant Joan de Déu
2021-2023
Universitat de Barcelona
2014-2021
Centro de Investigación Biomédica en Red
2020-2021
Institute of Research and Innovation Parc Tauli
2017-2020
Centro de Investigación Biomédica en Red de Salud Mental
2014-2020
Instituto de Salud Carlos III
2014-2020
Abstract Recent research suggests that neuroplastic and neuroinflammatory changes may account for the mode of action electroconvulsive therapy (ECT), although extant data do not allow a clear disambiguation between these two hypotheses. Multimodal neuroimaging approaches (for example, combining structural metabolic information) help in clarifying this issue. Here we aimed to assess longitudinal (i) regional gray matter (GM) volumes (ii) hippocampal metabolite concentrations throughout an...
Despite knowledge of amygdala involvement in fear and anxiety, its contribution to the pathophysiology obsessive-compulsive disorder (OCD) remains controversial. In context neuroimaging studies, it seems likely that heterogeneity might have contributed a lack consistent findings.To assess influence OCD symptom dimensions on responses well-validated emotional face-matching paradigm.Cross-sectional functional magnetic resonance imaging (fMRI) study 67 patients with age-, gender-...
The etiology of anorexia nervosa is still unknown. Multiple and distributed brain regions have been implicated in its pathophysiology, implying a dysfunction connected neural circuits. Despite these findings, the role white matter has rarely assessed. In this study, we used diffusion tensor imaging (DTI) to characterize alterations microstructure clinically homogeneous sample patients with nervosa.Women (restricting subtype) healthy controls underwent DTI. We tract-based spatial statistics...
Patients with anorexia nervosa (AN) display impaired social interactions, implicated in the development and prognosis of disorder. Importantly, behavior is modulated by reward-based processes, dysfunctional at-brain-level reward responses have been involved AN neurobiological models. However, no prior evidence exists whether these neural alterations would be equally present contexts. In this study, we conducted a cross-sectional social-judgment functional magnetic resonance imaging (fMRI)...
Abstract: Exposure to acute and chronic stress has a broad range of structural effects on the brain. The brain areas commonly targeted in response models include hippocampus, amygdala, prefrontal cortex. Studies patients suffering from so-called stress-related disorders -embracing post-traumatic stress, major depressive anxiety disorders- have fairly replicated animal -particularly neuroendocrine inflammatory models- by finding alterations different areas, even early neurodevelopment....
Abstract Advances in the neuroscientific understanding of bodily autonomic awareness, or interoception, have led to hypothesis that human trait anxiety sensitivity (AS)—the fear arousal—is primarily mediated by anterior insular cortex. Despite broad appeal, few experimental studies comprehensively addressed this hypothesis. We recruited 55 individuals exhibiting a range AS and assessed them with functional magnetic resonance imaging (fMRI) during aversive conditioning. For each participant,...
Background Pathological worry is a hallmark feature of generalised anxiety disorder (GAD), associated with dysfunctional emotional processing. The ventromedial prefrontal cortex (vmPFC) involved in the regulation such processes, but link between vmPFC responses and pathological v . adaptive has not yet been examined. Aims To study association activity evoked by processing learned safety threat signals. Method In total, 27 unmedicated patients GAD 56 healthy controls (HC) underwent...
Background: PlayMancer is a video game designed to increase emotional regulation and reduce general impulsive behaviors, by training decrease arousal improve decision-making planning. We have previously demonstrated the usefulness of in reducing impulsivity improving bulimia nervosa (BN) patients. However, whether these improvements are actually translated into brain changes remains unclear. Objective: The aim this case study was report on 28-year-old Spanish woman with BN, examine...
Body image distortion is a core symptom of anorexia nervosa (AN), which involves alterations in self- (and other's) evaluative processes arising during body perception. At neural level, self-related information thought to rely on areas the so-called default mode network (DMN), which, additionally, shows prominent synchronised activity at rest.Twenty female patients with AN and 20 matched healthy controls were scanned using magnetic resonance imaging when: (a) viewing video clips their own...
The selection of a bitemporal (BT) or right unilateral (RUL) electrode placement affects the efficacy and side effects ECT. Previous studies have not entirely described neurobiological underpinnings such differential effects. Recent neuroimaging research on gray matter volumes is contributing to our understanding mechanism action ECT could clarify mechanisms BT RUL ECT.To assess whole-brain volumetric changes observed after treating patients with treatment-resistant depression ECT, authors...
Objectives There is growing evidence supporting a role for stressful life events (SLEs) at obsessive-compulsive disorder (OCD) onset, but neurobiological correlates of such effect are not known. We evaluated regional grey matter (GM) changes associated with the presence/absence SLEs OCD onset. Methods One hundred and twenty-four patients 112 healthy controls were recruited. Patients split into two groups according to presence (n = 56) or absence 68) disorder's A structural magnetic resonance...
Melancholic depression is a biologically homogeneous clinical entity in which structural brain alterations have been described. Interestingly, reports of melancholia include volume increases Cerebro-Spinal Fluid (CSF) spaces. However, there are no previous CSF using automated whole-brain voxel-wise approaches, as tissue classification algorithms traditionally regarded less reliable for segmentation. Here we aimed to assess volumetric melancholic and their correlates by means novel...