Javier Labad

ORCID: 0000-0003-2214-1886
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Obsessive-Compulsive Spectrum Disorders
  • Child and Adolescent Psychosocial and Emotional Development
  • Bipolar Disorder and Treatment
  • Mental Health and Psychiatry
  • Eating Disorders and Behaviors
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Diet and metabolism studies
  • Body Image and Dysmorphia Studies
  • Autism Spectrum Disorder Research
  • Pituitary Gland Disorders and Treatments
  • Maternal Mental Health During Pregnancy and Postpartum
  • Attention Deficit Hyperactivity Disorder
  • Mental Health Research Topics
  • Adrenal Hormones and Disorders
  • Child Abuse and Trauma
  • Hormonal Regulation and Hypertension
  • Treatment of Major Depression
  • Personality Disorders and Psychopathology
  • Psychosomatic Disorders and Their Treatments
  • Neuroendocrine regulation and behavior
  • Mental Health Treatment and Access
  • COVID-19 and Mental Health

Universitat Autònoma de Barcelona
2016-2025

Centro de Investigación Biomédica en Red de Salud Mental
2016-2025

Hospital de Mataró
2020-2025

Maresme Health Consortium
2020-2025

Instituto de Salud Carlos III
2012-2025

Corporació Sanitària Parc Taulí
2015-2024

Institute of Research and Innovation Parc Tauli
2017-2024

Instituto de Neurociencias
2022

Centro de Investigación Biomédica en Red
2020-2022

Institut Pere Mata
2010-2020

Recent studies have begun to look at gender differences in schizophrenia and first-episode psychosis an attempt explain the heterogeneity of illness. However, a number uncertainties remain. This paper tries summarize most important findings first-psychosis episodes. Several indicate that incidence is higher men. Most found age onset be earlier men than women. Findings on symptoms are less conclusive, with some authors suggesting suffer more negative while women affective symptoms. Premorbid...

10.1155/2012/916198 article EN Schizophrenia Research and Treatment 2012-01-01

Article AbstractBackground: The aim of our study was to assess whether there is a relationship between reproductive cycle events and the initiation or changes in symptoms obsessive-compulsive disorder (OCD). Method: Forty-six female outpatients meeting DSM-IV criteria for OCD completed semistructured interview at unit OCD. Dates data collection were from January 2001 December 2003. Results: In sample, onset occurred same year as menarche 22% (N = 10), pregnancy 2% 1), postpartum 7% 3),...

10.4088/jcp.v66n0404 article EN The Journal of Clinical Psychiatry 2005-04-15

The aim of our study was to assess the role gender in OCD symptom dimensions with a multivariate analysis while controlling for history tic disorders and age at onset OCD. One hundred eighty-six consecutive outpatients DSM-IV diagnosis were interviewed. Yale-Brown Obsessive-Compulsive Scale (YBOC-S), YBOC-S Symptom Checklist, Hamilton Depression Anxiety Scales administered all patients. Lifetime assessed inventory section Yale Global Tic Severity Scale. Age by direct interview. Statistical...

10.1002/da.20332 article EN Depression and Anxiety 2007-04-13

Increased activity of the hypothalamic-pituitary-adrenal (HPA) axis may underlie metabolic syndrome, but whether circulating cortisol levels predict cardiovascular end points is less clear. People with type 2 diabetes are at increased disease risk and thus suitable to study associations plasma risk.

10.1210/jc.2009-2112 article EN The Journal of Clinical Endocrinology & Metabolism 2010-02-03

The potential therapeutic utility of estrogens in schizophrenia is increasingly being recognized. Raloxifene, a selective estrogen receptor modulator, appears to act similarly on dopamine and serotonin brain systems. One previous trial by our team found that raloxifene was useful improve negative, positive, general psychopathological symptoms, without having the negative side effects estrogens. In this study, we assess treating other psychotic symptoms postmenopausal women with exhibiting...

10.1093/schbul/sbv149 article EN Schizophrenia Bulletin 2015-11-20

Brain-derived neurotrophic factor (BDNF) gene regulation has been linked to the pathophysiology of major depressive disorder (MDD). MDD patients show cognitive deficits, and altered BDNF a relevant role in neurocognitive functions. Our goal was explore association between genetic epigenetic variations with performance group healthy controls considering possible modulating factors. The sample included 134 subjects, 64 patients, 70 controls. Clinical data, childhood maltreatment, were assessed...

10.1038/s41398-019-0601-8 article EN cc-by Translational Psychiatry 2019-10-21

OBJECTIVE People with type 2 diabetes are at increased risk of cognitive impairment but the mechanism is uncertain. Elevated glucocorticoid levels in rodents and humans associated impairment. We aimed to determine whether fasting cortisol ability estimated lifetime change an elderly population diabetes. RESEARCH DESIGN AND METHODS This was a cross-sectional study 1,066 men women aged 60–75 years diabetes, living Lothian, Scotland (the Edinburgh Type Diabetes Study). Cognitive abilities...

10.2337/dc09-1796 article EN cc-by-nc-nd Diabetes Care 2010-01-22

Background: Environmental stressors are considered to play an important role in the triggering of mental disorders such as obsessive–compulsive disorder (OCD). Although there is extensive literature on traumatic life events, little known about nontraumatic but nonetheless stressful events (SLEs) OCD. The aim this study was establish whether OCD preceded by SLE presents a different clinical pattern compared non-SLE-preceded Methods: We interviewed 412 patients assess both SLEs at onset and...

10.1002/da.20792 article EN Depression and Anxiety 2011-02-09

The relationship between religiosity and different components of empathy was explored in schizophrenia patients. A total 81 stable patients 95 controls from the nearby community completed self-reported questionnaires assessing (through Interpersonal Reactivity Index, IRI). Patients with showed higher religiousness than they presented less perspective-taking empathic concern but increased personal distress IRI scores. Regression analyses unveiled an association schizophrenics after adjusting...

10.3390/bs10020053 article EN cc-by Behavioral Sciences 2020-02-05
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