A5033133499- Cannabis and Cannabinoid Research
- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Neurotransmitter Receptor Influence on Behavior
- Hepatitis C virus research
- Neuroscience and Neuropharmacology Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Bipolar Disorder and Treatment
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Personality Disorders and Psychopathology
- Substance Abuse Treatment and Outcomes
- Treatment of Major Depression
- Functional Brain Connectivity Studies
- Liver Disease Diagnosis and Treatment
- Sleep and Wakefulness Research
- Pregnancy and Medication Impact
- Mental Health Research Topics
- Prenatal Substance Exposure Effects
- Connective tissue disorders research
- Perfectionism, Procrastination, Anxiety Studies
- Attachment and Relationship Dynamics
- Healthcare professionals’ stress and burnout
- Schizophrenia research and treatment
- Mental Health Treatment and Access
Universitat de Barcelona
2016-2025
Centro de Investigación Biomédica en Red de Salud Mental
2016-2025
Departament de Salut
2023-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2015-2024
Hospital Clínic de Barcelona
2013-2023
National Council for Scientific and Technological Development
2008-2023
Universidade de São Paulo
2008-2021
Charité - Universitätsmedizin Berlin
2021
Kliniken Essen-Mitte
2021
Catalan Society of Family and Community Medicine
2021
Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic properties. However, no study to date investigated the effects this compound on pathological anxiety its underlying brain mechanisms. The aim present was investigate in patients with generalized social disorder (SAD) using functional neuroimaging. Regional cerebral blood flow (rCBF) at rest measured twice (99m)Tc-ECD SPECT 10 treatment-naïve SAD. In first session, subjects were given an...
<h3>Context</h3> Cannabis use can both increase and reduce anxiety in humans. The neurophysiological substrates of these effects are unknown. <h3>Objective</h3> To investigate the 2 main psychoactive constituents of<i>Cannabis sativa</i>(Δ9-tetrahydrocannabinol [Δ9-THC] cannabidiol [CBD]) on regional brain function during emotional processing. <h3>Design</h3> Subjects were studied 3 separate occasions using an event-related functional magnetic resonance imaging paradigm while viewing faces...
The Structured Clinical Interview for the DSM is one of most used diagnostic instruments in clinical research worldwide. current Clinician Version instrument (SCID-5-CV) has not yet been assessed respect to its psychometric qualities. We aimed assess validity and different reliability indicators (interrater test-retest, joint interview, face-to-face vs telephone application) SCID-5-CV a large sample 180 non-prototypical psychiatric patients based on interviews conducted by raters with levels...
Although lower brain volume has been routinely observed in individuals with substance dependence compared nondependent control subjects, the regions exhibiting have not consistent across studies. In addition, it is clear whether a common set of are involved regardless used or some effects specific. Resolution these issues may contribute to identification clinically relevant imaging biomarkers. Using pooled data from 14 countries, authors sought identify general and substance-specific...
<h3>Context</h3> <i>Cannabis sativa</i>use can impair verbal learning, provoke acute psychosis, and increase the risk of schizophrenia. It is unclear where<i>C sativa</i>acts in human brain to modulate learning induce psychotic symptoms. <h3>Objectives</h3> To investigate effects 2 main psychoactive constituents of<i>C sativa</i>, Δ9-tetrahydrocannabinol (Δ9-THC) cannabidiol, on regional function during paired associate learning. <h3>Design</h3> Subjects were studied 3 separate occasions...
OBJECTIVE: The authors’ goal was to assess the validity of DSM-IV diagnoses obtained with Spanish versions Psychiatric Research Interview for Substance and Mental Disorders (PRISM) Structured Clinical (SCID) compared longitudinal, expert, all data (LEAD) procedure in a group substance abusers. METHOD: A total 105 abusers recruited at drug abuse treatment center Barcelona, Spain, were assessed. PRISM SCID administered blindly by independent research interviewers. LEAD made two senior...
Cannabis sativa, the most widely used illicit drug, has profound effects on levels of anxiety in animals and humans. Although recent studies have helped provide a better understanding neurofunctional correlates these effects, indicating involvement amygdala cingulate cortex, their reciprocal influence is still mostly unknown. In this study dynamic causal modelling (DCM) Bayesian model selection (BMS) were to explore pure compounds C. sativa [600 mg cannabidiol (CBD) 10...
Objective:The purpose of this study was to assess whether joint hypermobility syndrome is more frequent in patients with panic disorder, agoraphobia, or both than control subjects and, if so, determine mitral valve prolapse modifies accounts part for the association.Method:A case-control conducted a general teaching hospital outpatient clinic. Subjects were 99 patients, newly diagnosed and untreated, two groups age- sex-matched subjects: psychiatric 64 medical who had never suffered from any...