A5077848496- Cannabis and Cannabinoid Research
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Diet, Metabolism, and Disease
- Schizophrenia research and treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health, Nursing, Elderly Care
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Psychology and Mental Health
- Mental Health Treatment and Access
- Psychedelics and Drug Studies
- GABA and Rice Research
- Neuroscience of respiration and sleep
- Treatment of Major Depression
- Occupational Health and Burnout
- Youth, Drugs, and Violence
- Epilepsy research and treatment
- Parkinson's Disease Mechanisms and Treatments
- COVID-19 and Mental Health
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Substance Abuse Treatment and Outcomes
National Council for Scientific and Technological Development
2014-2025
Universidade de São Paulo
2015-2024
Instituto de Neurociências e Comportamento
2012-2023
Fundação de Amparo à Pesquisa do Estado de São Paulo
2021-2023
Center for Translational Molecular Medicine
2018-2023
Universidade de Ribeirão Preto
2003-2022
Instituto Nacional de Ciência e Tecnologia Translacional em Medicina
2010-2020
Hospital Universitário da Universidade de São Paulo
2005-2020
Clinics Hospital of Ribeirão Preto
1991-2020
Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional
2012-2018
The Alcohol Use Disorders Identification Test (AUDIT) is an instrument used to screen for alcohol-related problems.It has been increasingly in many different countries both the original English-language version and its translated versions.Because of need screening instruments faster administration, shortened versions AUDIT have also developed.This study was aimed at expanding work by Berner colleagues (2007) attempt answer some remaining questions as well identify evaluate studies on...
Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic properties. However, no study to date investigated the effects this compound on pathological anxiety its underlying brain mechanisms. The aim present was investigate in patients with generalized social disorder (SAD) using functional neuroimaging. Regional cerebral blood flow (rCBF) at rest measured twice (99m)Tc-ECD SPECT 10 treatment-naïve SAD. In first session, subjects were given an...
<h3>Context</h3> Cannabis use can both increase and reduce anxiety in humans. The neurophysiological substrates of these effects are unknown. <h3>Objective</h3> To investigate the 2 main psychoactive constituents of<i>Cannabis sativa</i>(Δ9-tetrahydrocannabinol [Δ9-THC] cannabidiol [CBD]) on regional brain function during emotional processing. <h3>Design</h3> Subjects were studied 3 separate occasions using an event-related functional magnetic resonance imaging paradigm while viewing faces...
OBJETIVOS: Verificar a confiabilidade da "Entrevista Clínica Estruturada para o DSM-IV - Versão (SCID-CV)" traduzida português. MÉTODOS: Foram submetidos, duas entrevistas independentes (teste-reteste), 45 pacientes psiquiátricos em seguimento no Hospital das Clínicas Faculdade de Medicina Ribeirão Preto Universidade São Paulo (HC-FMRP/USP). Os dados foram analisados pelo Coeficiente Kappa (K). RESULTADOS: O ponderado foi excelente (Kw=0,83). A estatisticamente significante transtorno do...
Parkinson's disease (PD) has a progressive course and is characterized by the degeneration of dopaminergic neurons. Although no neuroprotective treatments for PD have been found to date, endocannabinoid system emerged as promising target.From sample 119 patients consecutively evaluated in specialized movement disorders outpatient clinic, we selected 21 without dementia or comorbid psychiatric conditions. Participants were assigned three groups seven subjects each who treated with placebo,...
The purpose of this study was to investigate whether the anxiolytic effect cannabidiol (CBD) in humans follows same pattern an inverted U-shaped dose-effect curve observed many animal studies. Sixty healthy subjects both sexes aged between 18 and 35 years were randomly assigned five groups that received placebo, clonazepam (1 mg), CBD (100, 300, 900 mg). underwent a test public speaking real situation (TPSRS) where each subject had speak front group formed by remaining participants. Each...
What is known and objective Cannabidiol (CBD) the main non-psychotropic component of Cannabis sativa plant. REM sleep behaviour disorder (RBD) a parasomnia characterized by loss muscle atonia during associated with nightmares active dreaming. We have described effects CBD in RBD symptoms patients Parkinson's disease. Cases summary Four treated had prompt substantial reduction frequency RBD-related events without side effects. new conclusion This case series indicates that able to control RBD.
Objective: Cannabidiol (CBD), one of the non-psychotomimetic compounds Cannabis sativa, causes anxiolytic-like effects in animals, with typical bell-shaped dose-response curves. No study, however, has investigated whether increasing doses this drug would also cause similar curves humans. The objective study was to compare acute different CBD and placebo healthy volunteers performing a simulated public speaking test (SPST), well-tested anxiety-inducing method. Method: A total 57 male subjects...
The effects of ipsapirone and cannabidiol (CBD) on healthy volunteers submitted to a simulated public speaking (SPS) test were compared with those the anxiolytic benzodiazepine diazepam placebo. Four independent groups 10 subjects received, under double-blind design, placebo or one following drugs: CBD (300 mg), (10 mg) (5 mg). Subjective anxiety was evaluated through Visual Analogue Mood Scale (VAMS) State-trait Anxiety Inventory (STAI). VAMS factor showed that attenuated SPS-induced while...
Background: This study was aimed at assessing the psychometric qualities of abbreviated versions Alcohol Use Disorders Identification Test (AUDIT‐3, AUDIT‐4, AUDIT‐C, AUDIT‐PC, AUDIT‐QF, FAST, and Five‐Shot) comparing them to 10‐item AUDIT CAGE in 2 samples Brazilian adults. Methods: The validity internal consistency scales were assessed a sample 530 subjects attended an emergency department Psychosocial Care Center for Drugs. Structured Clinical Interview DSM‐IV used as diagnostic...