A5063678131- Sleep and Wakefulness Research
- Sleep and related disorders
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Memory and Neural Mechanisms
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Obstructive Sleep Apnea Research
- Neuroscience and Music Perception
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Research Topics
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Body Image and Dysmorphia Studies
- Attention Deficit Hyperactivity Disorder
- Neural dynamics and brain function
- Autism Spectrum Disorder Research
- Neurobiology of Language and Bilingualism
- Restless Legs Syndrome Research
- Deception detection and forensic psychology
- Heart Rate Variability and Autonomic Control
- Impact of Technology on Adolescents
- Circadian rhythm and melatonin
- Child Development and Digital Technology
- Dementia and Cognitive Impairment Research
- Cognitive Abilities and Testing
University of Iowa
2021-2025
Massachusetts General Hospital
2016-2020
Harvard University
2016-2020
Athinoula A. Martinos Center for Biomedical Imaging
2016-2019
Istanbul University
2011-2016
University of Massachusetts Amherst
2010-2016
Boğaziçi University
2007-2009
Sleep enhances memories, particularly emotional memories. As such, it has been suggested that sleep deprivation may reduce posttraumatic stress disorder. This presumes memory consolidation is paralleled by a reduction in reactivity, an association not yet examined. In the present experiment, we used incidental task humans and obtained valence arousal ratings during two sessions separated either 12 h of daytime wake or including overnight sleep. Recognition accuracy was greater following...
Schizophrenia patients have correlated deficits in sleep spindle density and sleep-dependent memory consolidation. In addition to density, consolidation is thought rely on the precise temporal coordination of spindles with slow waves (SWs). We investigated whether this intact schizophrenia its relation motor procedural Twenty-one chronic medicated 17 demographically matched healthy controls underwent two nights polysomnography, training finger tapping sequence task (MST) second night testing...
Consolidation of declarative memories has been associated with slow wave sleep in young adults. Previous work suggests that, spite changes sleep, sleep-dependent consolidation may be preserved aging, although reduced relative to on adults shows consolidation, retrieval gradually becomes independent the hippocampus. To investigate whether are similarly reorganized over at neural level, we compared functional brain activation word pair recall following a nap and equivalent wake older SWS...
Abstract The life script account of the reminiscence bump in autobiographical memories suggests that cultural expectations about nature and timing transitional events lead to bump. empirical evidence for scripts is limited. We tested generality by looking at effects culture, gender cohorts. Turkish participants were asked (a) list seven most important a newborn or an elderly would experience during his/her lifetime (b) estimate prevalence, importance, age‐at‐event emotional valence each...
Non-rapid eye movement sleep (NREM) oscillations are critical for cognitive and affective processing. While several studies link anxiety depression symptoms to quality, a gap remains in elucidating the role of NREM physiology sleep-dependent processing affect symptoms. The goals present study were investigate consolidation emotional memory relations with state upon awakening non-clinical sample enriched trait anxiety. Forty-two participants recruited from larger cohort college students based...
Abstract Introduction NREM oscillations play a critical role in memory consolidation, yet their sleep-dependent processing of affect and anxiety symptoms remains poorly understood. The present study examines the links between oscillations, emotional memory, symptoms, negative investigates whether are altered individuals with elevated trait anxiety. Methods Forty-two non-help-seeking young adults (M = 19.3, SD 1.8 years; 77% female), high (n 26) vs moderate-to-low 16) levels were monitored...
Abstract In the present study, we have tested hypothesis that brain‐derived neurotrophic factor ( BDNF ) gene Val66Met polymorphism is associated with obsessive–compulsive disorder (OCD) and also investigated association between performance on tests measuring executive functions in a sample of patients OCD. A total 100 diagnosed OCD according to DSM‐IV criteria 110 control subjects were included this study. Single nucleotide (G/A) leading Val Met substitution at codon 66 was screened DNA...
Autism Spectrum Disorder (ASD) is thought to reflect disrupted development of brain connectivity characterized by white matter abnormalities and dyscoordination activity across regions that give rise core features. But there little consensus about the nature, timing location as quantified with diffusion-weighted MRI. Inconsistent findings likely small sample sizes, motion confounds heterogeneity, particularly different age ranges studies. We examined microstructural integrity major tracts in...
Abstract Sleep spindles, defining oscillations of non‐rapid eye movement stage 2 sleep (N2), mediate memory consolidation. Spindle density (spindles/minute) is a stable, heritable feature the electroencephalogram. In schizophrenia, reduced spindle correlates with impaired sleep‐dependent consolidation and promising treatment target. Measuring spindles also important for basic studies memory. However, overnight are expensive, time consuming require considerable infrastructure. Here we...
This study investigated episodic memory and metamemory for verbs nouns in patients who have cognitive impairments associated with Parkinson's disease (PD). PD healthy control participants were asked to recall word pairs provide feeling-of-knowing (FOK) judgments the items they unable recall. was followed by a 4-alternative recognition test. impaired both recognition, compared controls. In terms of metamemory, less confident their ability recognize unrecalled future Most important, accuracy...
Abstract There is converging evidence that abnormal thalamocortical interactions contribute to attention deficits and sensory sensitivities in autism spectrum disorder (ASD). However, previous functional MRI studies of connectivity ASD have produced inconsistent findings terms both the direction (hyper vs. hypoconnectivity) location group differences. This may reflect, part, confounding effects head motion during scans. In present study, we investigated resting‐state 8–25 year‐olds with...
Healthy midlife children of a parent with Alzheimer’s disease ([AD] N = 23; 9 male) participated in neuropsychological testing, and magnetic resonance imaging (MRI) brain volumetrics were obtained. In all, 35% the sample apolipoprotein E (ApoE)-e4 positive (n 8; 5 male). The ApoE-e4 group exhibited significantly slower performances on an executive function processing speed measure had less white matter volume than non-ApoE-e4 group. Lesser was correlated speed. Processing changes might be...