A5079670930- Microbial Community Ecology and Physiology
- Microbial metabolism and enzyme function
- Enzyme-mediated dye degradation
- Lignin and Wood Chemistry
- Gut microbiota and health
- Connective tissue disorders research
- Microbial Metabolism and Applications
- Environmental DNA in Biodiversity Studies
- Protist diversity and phylogeny
- Genomics and Phylogenetic Studies
- Parasites and Host Interactions
- Marine and coastal ecosystems
- Bone fractures and treatments
- Wastewater Treatment and Nitrogen Removal
- Aquatic Ecosystems and Phytoplankton Dynamics
- Metalloenzymes and iron-sulfur proteins
- Biochemical and biochemical processes
- Coastal wetland ecosystem dynamics
- Methane Hydrates and Related Phenomena
- Elbow and Forearm Trauma Treatment
- Hip disorders and treatments
- Neurofibromatosis and Schwannoma Cases
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Sarcoma Diagnosis and Treatment
Central South University
2016-2025
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2025
University of Electronic Science and Technology of China
2025
Hunan Children's Hospital
2018-2024
Yan'an University
2024
Tianjin University of Science and Technology
2024
Hohai University
2024
University of South China
2018-2023
Xiangya Hospital Central South University
2023
Chinese Academy of Sciences
2013-2022
Abstract Background Lignin materials are abundant and among the most important potential sources for biofuel production. Development of an efficient lignin degradation process has considerable production a variety chemicals, including bioethanol. However, using current methods is inefficient. Given their immense environmental adaptability biochemical versatility, bacterial could be used as valuable tool rapid lignin. Kraft (KL) polymer by-product pulp paper industry resulting from alkaline...
Unraveling the relative importance of ecological processes regulating microbial community structure is a central goal in ecology. Here, we used high-throughput sequencing to examine contribution selective and neutral assembly abundant rare subcommunities from three subtropical bays China. We found that bacterial taxa were distinctly different diversity, despite similar biogeographic patterns strong distance-decay relationships, but dispersal was more limited than taxa. Furthermore,...
Microorganisms play pivotal roles within aquatic ecosystems, affecting their structure, functioning and services. However, little is known about the effects of water stratification mixing on microbial community dynamics in subtropical reservoirs. In this study, we explored vertical seasonal patterns diversity Dongzhen Reservoir (southeast China). Quantitative PCR, quantitative RT-PCR 454 pyrosequencing were used for an in-depth characterization bacterial across time (every three months one...
The aim was to obtain evidences for lignin degradation by unicellular bacterium Comamonas sp. B-9.Comamonas B-9 inoculated into kraft lignin-mineral salt medium (KL-MSM) at pH 7·0 and 30°C 7 days of incubation. bacterial growth, chemical oxygen demand (COD) reduction, secretion ligninolytic enzymes productions low-molecular-weight compounds revealed that able degrade (KL). COD in KL-MSM reduced 32% after maximum activities manganese peroxidase (MnP) 2903·2 U l(-1) laccase (Lac) 1250 were...
Microbes are key components of aquatic ecosystems and play crucial roles in global biogeochemical cycles. However, the spatiotemporal dynamics planktonic microbial community composition riverine still poorly understood. In this study, we used denaturing gradient gel electrophoresis PCR-amplified 16S 18S rRNA gene fragments multivariate statistical methods to explore patterns driving factors bacterial eukaryotic communities subtropical Jiulong River, southeast China. Both varied significantly...
Kraft lignin (KL) is the major pollutant in black liquor. The bacterial strain Pandoraea sp. B-6 was able to degrade KL without any co-substrate under high alkaline conditions. At least 38.2 % of chemical oxygen demand and 41.6 color were removed 7 days at concentrations from 1 6 g L(-1). optimum pH for degradation 10 temperature 30 °C. greatest activities 2,249.2 U L(-1) manganese peroxidase 1,120.6 laccase detected on third fifth day 10, respectively. Many small molecules, such as cinnamic...
Abstract BACKGROUND Noninvasive prenatal testing (NIPT) for monogenic diseases by use of PCR-based strategies requires precise quantification mutant fetal alleles circulating in the maternal plasma. The study describes development and validation a novel assay termed single-molecule amplification resequencing technology (cSMART) counting single allelic molecules Here we demonstrate suitability cSMART NIPT, with Wilson Disease (WD) as proof concept. METHODS We used Sanger whole-exome...
Both phytoplankton and bacteria are key abundant components of aquatic ecosystems play pivotal roles in maintaining ecosystem structure function. However, the extent to which community succession influences changes bacterial composition (BCC) is largely unknown. In this study, we evaluated correlations between communities determined relative contribution temporal variation BCC a subtropical drinking water reservoir (Tingxi Reservoir, southeast China). Bacterial were investigated by...
Abstract Recent research has greatly expanded our understanding of microbial metacommunities in aquatic ecosystems. However, patterns at the mesoscale are still poorly understood. We present first simultaneous analyses biogeography and co‐occurrence generalists specialists marine bacteria from three subtropical bays China test for signals ecological processes (i.e., stochastic deterministic processes) community assembly. Results showed that compared to specialists, bacterial were less...
Lanthanide-dependent alcohol dehydrogenases have recently emerged as environmentally important enzymes, most prominently represented in methylotrophic bacteria. The diversity of these their environmental distribution, and biochemistry, well evolutionary relationships with calcium-dependent counterparts remain virtually untapped. Here, we make advances toward understanding lanthanide-dependent methylotrophy by assessing the distribution XoxF4 XoxF5 clades lanthanide methanol among,...
Invasion by exotic plant species can alter ecosystem function and reduce native diversity, but relatively little is known about their effects on belowground microbial communities. Here we investigated the of cordgrass (Spartina alterniflora) invasion distribution soil bacterial communities in a mangrove nature reserve Jiulong River Estuary, southeast China using high-throughput sequencing 16S rRNA gene multivariate statistical analysis. Our results showed that S. alterniflora altered...
Abstract As the Human Microbiome Project (HMP) progresses, relationship between microbes and human health has been receiving increasing attention. A growing number of reports support correlation cancer microbes. However, most studies have focused on bacteria, rather than fungal communities. In this study, we studied alteration in lung mycobiome patients with non-small-cell (NSCLC) using metagenomic sequencing qPCR. The higher diversity more complex network were observed NSCLC. addition,...
Viruses, as the most prolific entities on Earth, constitute significant ecological groups within freshwater lakes, exerting pivotal roles. In this study, we selected Chaohu Lake, a representative eutrophic lake in China, our research site to explore community distribution, driving mechanisms, and potential functions of diverse viral communities, intricate virus–host interaction systems, overarching influence viruses global biogeochemical cycling.
We describe experiments that follow species dynamics and gene expression patterns in synthetic bacterial communities including compete for the single carbon substrate supplied, methane, unable to consume which could only succeed through cooperative interactions. demonstrate these mostly select two functional guilds, methanotrophs of family Methylococcaceae non-methanotrophic methylotrophs Methylophilaceae, taxonomic guilds outcompeting all other included mix. The metatranscriptomics analysis...