- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- LGBTQ Health, Identity, and Policy
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Syphilis Diagnosis and Treatment
- Science and Education Research
- Sexuality, Behavior, and Technology
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Bacillus and Francisella bacterial research
- HIV/AIDS oral health manifestations
- COVID-19 epidemiological studies
- Health Systems, Economic Evaluations, Quality of Life
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis C virus research
- African Sexualities and LGBTQ+ Issues
- Zoonotic diseases and public health
- Frailty in Older Adults
- Viral Infections and Outbreaks Research
Fundação Oswaldo Cruz
2016-2025
Instituto Evandro Chagas
2014-2025
Faculdades Oswaldo Cruz
2022-2023
Creative Commons
2023
University of Buea
2022
Boston University
2022
Soroti Hospital
2022
Escola Nacional de Saúde Pública
2022
Instituto Nacional de Salud Pública
2022
Instituto Nacional de Psiquiatría
2022
Abstract Introduction : The efficacy of pre‐exposure prophylaxis (PrEP) in preventing sexual acquisition human immunodeficiency virus (HIV) is well established. Little known about the feasibility PrEP implementation middle‐income settings with concentrated epidemics among men who have sex (MSM) and transgender women (TGW). Methods Brasil a prospective, multicentre, open‐label demonstration project assessing delivery context Brazilian Public Health System. HIV‐uninfected MSM TGW 3 referral...
We conducted a web-based survey to understand the impact of social distancing measures on Brazilian MSM and transgender/non-binary lives. A total 3486 respondents were included in this analysis great majority cismen (98%). The median age was 32 years (IQR: 27-40), 44% non-white, 36% low schooling 38% income. Most participants reported HIV negative/unknown status (77%). Participants on-PrEP more condomless anal sex than those off-PrEP. Conversely, 24% off-PrEP at substantial HIV-risk....
HIV disproportionally affects key populations including men who have sex with (MSM). prevalence among MSM varies from 17% in Brazil and Mexico to 13% Peru, whereas it is below 0.5% for the general population each country. Pre-exposure prophylaxis (PrEP) emtricitabine/tenofovir being implemented context of combination prevention. Reports on willingness use PrEP started emerge over last few years. Previously reported factors associated include awareness, higher sexual risk behavior, previous...
COVID-19 public health responses such as social distancing and community containment measures protocols are critical to preventing containing the spread of coronavirus. Brazil accounts for almost half Latin American HIV cases Rio de Janeiro is city with second largest number AIDS. Clinical appointments pharmacy antiretroviral refills may be impaired due restricted traffic possible lockdowns, people living those using PrEP from accessing needed antiretrovirals. We hereby describe telemedicine...
Although gay, bisexual, and other cisgender men who have sex with (MSM) transgender women the highest HIV burden in Latin America, pre-exposure prophylaxis (PrEP) implementation is poor. We aimed to assess feasibility of same-day oral PrEP delivery Brazil, Mexico, Peru.Implementation (ImPrEP) was a prospective, single-arm, open-label, multicentre study conducted Brazil (14 sites), Mexico (four Peru (ten sites). MSM were eligible participate if they aged 18 years or older, HIV-negative,...
Abstract Introduction The HIV epidemic continues to disproportionately impact Latin‐American transgender women (TGW). We assessed factors associated with long‐term pre‐exposure prophylaxis (PrEP) engagement and adherence among TGW enrolled in the Implementation of PrEP (ImPrEP) study, largest demonstration study Latin America. Methods HIV‐negative aged ≥18 years reporting 1+eligibility criteria 6 months prior enrolment (e.g. sex partner known be living HIV, condomless anal [CAS],...
By October 30, 2022, 76,871 cases of mpox were reported worldwide, with 20,614 in Latin America. This study reports characteristics a case series suspected and confirmed at referral infectious diseases center Rio de Janeiro, Brazil.
Background The 2022 multicountry mpox outbreak positioned the condition as a public health emergency of international concern. By May 2023, Brazil ranked second globally in cumulative number cases and deaths. higher incidence among gay other men who have sex with current deepens stigma discrimination against sexual gender minorities (SGM). This might worsen structural barriers impacting access to services, which ultimately leads undertesting underreporting cases. There are no data available...
Brazil has the largest population of individuals living with HIV/AIDS in Latin America a disproportional prevalence infection among men who have sex (MSM). This study evaluated PrEP awareness by age (18-24, 25-35, ≥36 years), its associated factors and willingness to use HIV prevention technologies MSM using GSN app Brazil. Inclusion criteria were ≥18 years-old, cisgender HIV-negative serostatus. Of 7242 individuals, 4136 (57%) completed questionnaire. was reported 51% (though lower aged...
In March 2020, telemedicine and HIV self-testing were adopted by Brazilian Public Health services to minimize disruptions in pre-exposure prophylaxis (PrEP) access delivery during the COVID-19 pandemic. To understand acceptability of PrEP teleconsultation self-testing, we conducted a web-based study social distancing period (April–May, 2020) among men who have sex with transgender/non-binary individuals using media. Out 2375 negative respondents, 680 reported use included this analysis....
Abstract Introduction We aimed to evaluate daily oral pre‐exposure prophylaxis (PrEP) uptake, retention, and adherence predictors of study non‐attendance low PrEP in a Brazilian trans‐specific 48‐week (PrEParadas). Methods enrolled transgender women (TGW) engaging high‐risk sexual behaviours between August 2017 December 2018. was based on tenofovir diphosphate concentrations dried blood spots (DBS). used random effects logistic regression models ordinal estimate the odds having missed visit...
Resumo: A profilaxia pré-exposição ao HIV (PrEP) tem sido considerada uma estratégia fundamental para o controle da epidemia de HIV/aids, e desde 2018 objeto estudo implementação (Estudo ImPrEP Stakeholders), realizado no Brasil, México Peru. Um componente qualitativo desse foi desenvolvido com objetivo identificar os contextos sociais estruturais que envolvem organizam a oferta serviços PrEP as subjetividades dos atores envolvidos diferentes percepções podem impactar efetivação dessa...
(1) Background: We aimed to estimate sexualized drug use (SDU) prevalence and its predictors among sexual gender minorities. (2) Methods: used an online on-site survey enroll sexual/gender minorities people between October–December/2020, multivariate logistic regression obtain SDU correlates. (3) Results: enrolled 3924 individuals (280 transgender women [TGW], 3553 men who have sex with [MSM], 91 non-binary), 29.0% currently on pre-exposure prophylaxis (PrEP). was 28.8% (95% confidence...
Introduction Black and Hispanic/Latinx cisgender men who have sex with (MSM), transgender women, men, gender nonbinary (TGNB) individuals been historically underrepresented in HIV pre-exposure prophylaxis (PrEP) clinical trials. There is an urgent need for ongoing engagement communities that the most impacted by diverse representation Here we describe strategic approaches undertaken PURPOSE 2 trial to optimize of individuals. Methods results Phase 3 evaluating safety efficacy lenacapavir as...
HIV incidence estimation is critical for monitoring the epidemic dynamics and effectiveness of public health prevention interventions. We aimed to identify sexual gender minorities (SGM) with recent infections, factors associated infection, estimate annualised rates.
Although strong scientific evidence of the efficacy and effectiveness treatment-as-prevention (TasP) is available, full endorsement "Undetectable = Untransmittable" (U U) "zero-risk" messages could be improved. Increasing knowledge about HIV transmission, prevention treatment a critical component care efforts. The study assessed transmission strategies, perceived accuracy slogan U among sexual gender minorities (SGM) in Brazil.