A5101626928- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Cancer, Lipids, and Metabolism
- Orthopedic Infections and Treatments
- Oral and gingival health research
- Inflammatory Biomarkers in Disease Prognosis
- Vascular anomalies and interventions
- Total Knee Arthroplasty Outcomes
- Attention Deficit Hyperactivity Disorder
- Metastasis and carcinoma case studies
- Digital Holography and Microscopy
- Image Processing Techniques and Applications
- Orthopaedic implants and arthroplasty
- Optical measurement and interference techniques
- Gallbladder and Bile Duct Disorders
- Neural and Behavioral Psychology Studies
- Liver Disease Diagnosis and Treatment
- Biological and pharmacological studies of plants
- Medical Imaging and Analysis
- Neurofibromatosis and Schwannoma Cases
- Genetic and Kidney Cyst Diseases
Hyogo Social Welfare Corporation
2025
Kobe University
2025
Tokushima University
2023
Fukushima Medical University
2009-2022
Tokushima Prefectural Central Hospital
2022
Takatsuki General Hospital
2020-2021
Mater Health Services
2021
Ritsumeikan University
2003-2019
Hiroshima University Hospital
2017
Nara Medical University
2017
Little is known about the roles of Notch signaling in cholangiocarcinoma (CC). The expression hairy and enhancer split 1 (Hes-1) has not been investigated yet resected specimens CC. reported to be related cancer stem cell (CSC) like properties some malignancies. Our aim investigate participation extrahepatic CC (EHCC) evaluate efficacy cells with CSC-like by blockade. First, Notch1, 2, 3, 4 Hes-1 was examined immunohistochemistry 132 EHCC specimens. clinicopathological characteristics...
Abstract Purpose Open wedge distal tuberosity tibial osteotomy (owDTO) is an effective treatment for varus knee osteoarthritis. Hinge fracture a major complication, and hinge position contributing factor. This study aimed to investigate the relationship between fractures. Methods examined 42 knees that underwent owDTO. The level of proximal tibiofibular joint (PTFJ) was investigated on postoperative computed tomography (CT) images measuring distances angles around area. Based previous...
402 Background: With the much-improved surgical techniques of hepatic lobectomy, but long-term survival patients undergoing such surgery remains far from satisfactory. Then, to improve prognosis cholangiocarcinoma patients, we have applied neoadjuvant chemoradiation therapy followed by conventional resection for possibly resectable cholangiocarcinoma, named NACRAC. Here, analyzed and evaluated Phase II (P-2) study. Methods: Patients with histologically or cytologically confirmed...
Abstract Background Liver fibrosis is a risk factor for hepatectomy but cannot be determined accurately before because diagnostic procedures are too invasive. Magnetic resonance elastography (MRE) can determine liver stiffness (LS), surrogate marker assessing fibrosis, non-invasively. The aim of this study was to investigate whether the LS value by MRE predictive major complications after hepatectomy. Methods This prospective enrolled consecutive patients who underwent hepatic resection...
Although serum albumin has been reported to be useful as a prognostic biomarker for various malignancies, it is not suitable prognosis of patients with hepatocellular carcinoma (HCC) due impaired liver function. We aimed determine whether transthyretin (TTR) level can used novel biomarker.Serum levels TTR, well other nutritional and inflammatory parameters including angiogenic factors, were examined in 25 HCC.The TTR exhibited statistically significant inverse correlation interleukin-6 (r =...
Early intra-abdominal infection (IAI) following pancreaticoduodenectomy (PD) is an initial event relating to morbidities caused by postoperative pancreatic fistula (POPF). The aims of this study were determine factors associated with IAI, and investigate its impact on outcome.
To reduce the stress on medial tibial cortex and to decrease risk of fracture, a varus cut tibia appears be reasonable alternative orthogonal by conventional methods.We present new instrument procedure, which enables for Oxford unicompartmental knee arthroplasty.We used custom-made, slidable fixator instead standard set extramedullary rod leg.We also made numeric formula chart arrange cutting angle using length mediolateral shift distal end longitudinal extension rod.A up 4.5° can...
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant inherited disorder that classically characterized by the presence of neoplastic lesions parathyroid glands, anterior pituitary gland, and pancreas. However, MEN1 with concomitant pheochromocytoma extremely rare. We report a case pheochromocytoma. A 44-year-old Japanese man, who had undergone total parathyroidectomy due to primary hyperparathyroidism at age 18, was referred our hospital complaint large abdominal tumor. He...
In Oxford unicompartmental knee arthroplasty, the relationship between mobile bearing and vertical wall of tibial tray is important in preventing dislocation. Separation from can cause spinning with an increased risk subsequent We report on intraoperative adjustment performed to prevent spinning. After femoral bone cutting flexion extension gap, trial inserted bearing-vertical distance evaluated before preparation using template trial. case separation, it be resolved by medialization or...
Purpose/Aim: Although several prognostic factors for extrahepatic cholangiocarcinoma (EHC) have been reported, preoperative yet to be established. We investigated the serum concentration of angiogenic, inflammatory, and nutritional parameters. Materials Methods: Twenty-five patients with EHC were enrolled before starting treatment. Preoperative identified using multivariate analyses. Results: The soluble intercellular adhesion molecule-1 (sICAM-1) levels significantly higher in (436.0 ± 43.2...
Median arcuate ligament syndrome is a clinical condition in which the median causes compression and narrowing of celiac artery. It has been reported that collateral pathways, developed by decrease blood flow from artery, facilitates formation aneurysms. Aneurysms around pancreas particular require aggressive therapeutic intervention, because rupture can be fatal. We herein report two cases pancreaticoduodenal aneurysms associated with treated coil embolization incision. Case 1 required...
The identification of novel biomarkers for hepatocellular carcinoma (HCC) is great importance in improving the outcome patients with HCC. present study aimed to determine prognostic significance soluble intercellular adhesion molecule (sICAM)‑1 prospectively collected clinicopathological data from 36 HCC who had undergone successful hepatectomy. An analysis using a receiver operating characteristic (ROC) curve was performed cut‑off value predicting prognosis. Overall survival (OS),...
Despite strict criteria for the observation of intraductal papillary mucinous neoplasm (IPMN), it remains difficult to distinguish invasive IPMN from non-invasive IPMN. The aim present study was identify an indicator retrospectively evaluated 53 patients (28 with non‑invasive and 25 IPMN) who underwent resection IPMN, examined usefulness MIB‑1 labeling index as indexes in were significantly higher compared those (P<0.001). A receiver operating characteristic curve revealed that area under...
Dual SC screw (DSCS) is a unique concept internal fixation device consisting of sliding and barrel assembly that enables compression force to be applied the femoral neck fracture side. There are two types barrels: thread plate has one-holed side prevent varus deformity. We report clinical results application DSCS with combined use as an anti-rotational hip screw.We used for fractures in 196 joints 190 patients between November 2005 June 2017. Among them, 70 hips 66 (13 men 53 women; mean...
The trabecular bone score (TBS) is reported to be an independent predictor of fracture risk in patients with primary or secondary osteoporosis. However, there have been few reports on its use the Japanese population. This study aimed investigate factors for vertebral population and evaluate usefulness TBS.This cross-sectional involved 279 aged 60-90 years whom mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA). TBS calculated based DXA scans. presence absence...
Acinar cell cystadenocarcinoma is a rare malignant epithelial neoplasm of the pancreas with diffusely cystic, gross architecture in which cysts are lined neoplastic cells that demonstrate evidence pancreatic exocrine enzyme production. This 10th case has been reported literature. A 77-year-old male complaining left hypochondrial pain was referred to our hospital for treatment tumor. huge, honeycomb-structured tumor detected tail. Distal pancreatectomy total resection residual stomach and...
An imaging system with a focusing mechanism based on perfect perspective projection was devised using varifocal mirror to achieve high-quality three-dimensional and precise measurement of shapes. It constructed so that the placed at object focal point image-taking lens. The lens fixed when mirror. Magnification exactly equal ratio length distance from This held magnifications larger than unity. surface shape spherical dent (3.5 mm in diameter) could accurately be measured shape-from-focus...