Aleksandr Krutko

ORCID: 0000-0002-2570-3066
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Medical Imaging and Analysis
  • Musculoskeletal pain and rehabilitation
  • Scoliosis diagnosis and treatment
  • Cervical and Thoracic Myelopathy
  • Pelvic and Acetabular Injuries
  • Medical and Biological Sciences
  • Anesthesia and Pain Management
  • Myofascial pain diagnosis and treatment
  • Spinal Hematomas and Complications
  • Medical and Biological Ozone Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Head and Neck Surgical Oncology
  • Orthopaedic implants and arthroplasty
  • Pregnancy-related medical research
  • Pain Management and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Orthopedic Surgery and Rehabilitation
  • Environmental and biological studies
  • Plant Toxicity and Pharmacological Properties
  • Enhanced Recovery After Surgery
  • Advanced Causal Inference Techniques
  • Brain Metastases and Treatment
  • Pleural and Pulmonary Diseases

Central Scientific Research Institute of Traumatology and Orthopedics
2020-2025

Novosibirsk Scientific Research Institute of Traumatology and Orthopedics. Ya.L. Tsivyan
2016-2021

Université de Strasbourg
2021

Tomsk National Research Medical Center
2021

Ministry of Health of the Russian Federation
2019

Yan'an University
2018

Several minimally invasive lumbar interbody fusion techniques may be used as a treatment for spondylolisthesis to alleviate back and leg pain, improve function provide stability the spine. Surgeons choose an anterolateral or posterior approach surgery however, there remains lack of real-world evidence from comparative, prospective studies on effectiveness safety with relatively large, geographically diverse samples involving multiple surgical approaches.To test hypothesis that approaches are...

10.1016/j.spinee.2023.05.013 article EN cc-by-nc-nd The Spine Journal 2023-05-25

The fast track technology means a complex of targeted measures involving rational preoperative preparation, minimally invasive surgery, regional anesthesia and short-acting anesthetics, early postoperative rehabilitation. Elucidating the possibility applying in neurosurgery, particular spinal is extremely topical. This associated with epidemiological data fact that techniques used neurosurgery are highly expensive.The study objective was implementation subsequent analysis its use after...

10.17116/neiro20168045-12 article RU Burdenko s Journal of Neurosurgery 2016-01-01

Annuloplasty is the modern pathogenetically substantiated surgical technique for managing lumbar disc herniation that improves outcomes of limited microdiscectomy. Nevertheless, rare complications require using a special strategy and customizing treatment reoperation.We present clinical case patient with transpedicular interbody fixation reoperation after annuloplasty Barricaid closure device. The aim this article to demonstrate opportunities patients involving device as final stage ways...

10.1016/j.ijscr.2016.04.043 article EN International Journal of Surgery Case Reports 2016-01-01

Patients with symptomatic single-level combination of degenerative stenosis and low-grade spondylolisthesis are often treated by nerve root decompression spinal fusion. The gold standard is traditional open fusion, but minimally invasive method more prevailing. However, there lack high-quality studies comparing these two techniques in order to obtain the advantages certain indications use one methods. current study includes clinical, safety radiological endpoints determine effectiveness...

10.1136/bmjopen-2020-041134 article EN cc-by-nc BMJ Open 2021-03-01

An analytical review of the literature on problem segmental spinal instability is presented. The relevance investigated field spine surgery beyond doubt. At present, a number issues related to definition concept instability, its biomechanical basis, diagnostic criteria and treatment tactics remain debatable. paper highlights views world’s leading researchers understanding various aspects this pathology in surgery. research materials were abstracts from PubMed Scopus databases, papers...

10.14531/ss2017.3.74-83 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2017-09-15

ABSTRACT Objective: The aim of the study was to investigate clinical and radiological results using annular closure device in patients with lumbar disc herniation (LDH). Methods: involved 120 LDH operated on by limited discectomy Barricaid device. A literature review conducted evaluate effectiveness annuloplasty. Results: All showed postoperative regression radicular pain syndrome were mobilized day surgery. correlation between removed nucleus pulposus changes DHI studied linear regression....

10.1590/s1808-185120181703193832 article EN cc-by Coluna/Columna 2018-07-01

Previous studies have demonstrated bone-anchored annular closure to significantly reduce reherniation and reoperation rates after lumbar discectomy in patients with large defects. It is important identify the prognostic factors that may be associated successful treatment. This study aimed predictors of treatment success disc herniation treated limited microdiscectomy supplemented by a device (ACD).This was retrospective analysis 133 consecutive ACD. Treatment defined as ≥24% improvement...

10.14444/7005 article EN The International Journal of Spine Surgery 2020-02-01

Objective. To analyze the features of surgical treatment children and adolescents with herniated discs radicular compression symptoms. Material Methods . A retrospective multicenter study 34 patients juvenile osteochondrosis mean age 15.4 years was performed. Surgical included disc puncture methods, microdiscectomy through posterior approach, anterior discectomy, dynamic rigid stabilization, replacement fibrous ring defect. Results Positive clinical effect complete relief pain achieved in...

10.14531/ss2017.1.68-77 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2017-03-10

Results of comparative study posterior interbody fusion (PLIF) and transforaminal (TLIF) in degenerative lumbar spine pathology are presented. Total number patients was 101. In 47 (1st group) transpedicular fixation, decompression with one cage performed. 54 (2nd fixation via posteromedial approach, intracanal neurovascular structures two implants applied. Complex evaluation surgical treatment results performed 52 6-12 months after surgery. It shown that application either the techniques...

10.17816/vto201219112-21 article EN N N Priorov Journal of Traumatology and Orthopedics 2012-03-15

Lumbar intervertebral disc degeneration (DD) disease is one of the main risk factors for low back pain and a leading cause population absenteeism disability worldwide. Despite variety biological studies, lumbar DD not yet fully understood, partially because there are only few studies that use systematic integrative approaches. This urges need integrate different omics (including genomics transcriptomics) measured on samples within single cohort. protocol describes disease-oriented Russian...

10.1371/journal.pone.0267384 article EN cc-by PLoS ONE 2022-05-13

To date, a large amount of retrospectively collected data about treatment neurosurgical pathology have been accumulated. Modern methods medical statistics are necessary for correct interpretation the data. The article purpose is to demonstrate application one modern methods, Propensity Score Matching (PSM), in neurosurgery. use PSM avoids misinterpretation and obviates errors planning further prospective studies. For past 10 years, number published international PSM-based studies has...

10.17116/neiro201882152-58 article RU Burdenko s Journal of Neurosurgery 2018-01-01

Abstract Background: The rate of scoliosis in syringomyelia patients ranges from 25 to 74.4%. In turn, occurs 1.2% 9.7% patients. Aim: To evaluate outcomes surgical correction the scoliotic deformity Materials and methods: Between 1996 2015, 3120 with various etiologies were treated at Clinic for Child Adolescent Vertebrology Novosibirsk Research Institute Traumatology Orthopedics. We conducted a retrospective analysis syringomyelia-associated cases that required correction. Results:...

10.1515/folmed-2017-0099 article EN Folia Medica 2018-06-01

Introduction. Analysis of the modern literature shows that number children complaining low back pain varying intensity in spine increases annually. Publications on surgical treatment juvenile osteochondrosis were scarce. Currently, there are no algorithms for choosing a and adolescents with lumbar pathology, particularly high-grade listhesis, methods terms treatment, use reduction maneuvers remain debatable. There high-quality evidence studies. Aim. This study aimed to summarize experience...

10.17816/ptors6437-47 article EN Pediatric Traumatology Orthopaedics and Reconstructive Surgery 2018-12-29

Objective . To analyze the early clinical and radiological outcomes of lumbar spine fusion in patients with degenerative sagittal imbalance. Material Methods The data 45 who were operated on sequentially using a combination surgical methods for vertebrogenic pain syndrome (or) neurological deficit had violation balance origin analyzed. All underwent anterior spinal at L4–L5, L5–S1 levels to correct restore lower lordosis. next stage was decompression through posterior approach, if necessary...

10.14531/ss2020.2.49-57 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2020-06-17

Longitudinal study of cervical MR in patients with degenerative disc disease (DDD).To evaluate the evolution changes C2-D1 segments and to assess association magnetic resonance imaging (MRI) parameters clinical symptoms after surgical treatment DDD.The spine is poorly understood. Endplate defects can be great importance progressive degeneration (DD). Clarification this predictor may important determining tactics included who had 2-years' follow-up fusion for spondylotic radiculo-...

10.1097/brs.0000000000004007 article EN Spine 2021-02-16

Objective. To compare histological changes after coblation and denervation of intervertebral disc in a model degenerative-dystrophic lesion the spine. Material Methods. The experiment included 15 mongrel dogs, which degenerative lumbar were initiated. Discs affected by cold plasma chemical denervation. Animals sacrificed at 1, 3, 6 months. Specimens subjected to examination. Results. In early period alcohol injection marked cell proliferative response over entire was observed. Coblation...

10.14531/ss2011.4.51-57 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2011-12-20

Objective. To study biochemical changes in proteoglycans (PGs) of intervertebral disc tissues and stages their degeneration patients with recurrent herniation. Material Methods. A retrospective analysis radiological parameters primary hernias discs from 16 who were reoperated on at the same level within three years was performed. Degenerated classified according to Pfirrmann’s criteria. The quantity glycosaminoglycans (GAGs) hernia surrounding annulus fibrosus determined by analytical...

10.14531/ss2012.2.87-93 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2012-06-06

To perform a comparative analysis of outcomes in patients with lumbar spine segmental instability who underwent surgical treatment using transforaminal interbody fusion (TLIF) and direct lateral (DLIF) techniques.The multicenter study involved 209 surgery for instability. Long-term (up to 2 years) were studied 134 patients: the first group (98 patients) traditional transpedicular stabilization vertebral segments; second (36 combination segments. We used standard checkpoints monitoring...

10.17116/neiro201781669-80 article RU Burdenko s Journal of Neurosurgery 2017-01-01

The paper presents analytical review of the literature on problem surgical treatment patients with intradural migration intervertebral disc hernias and a clinical case herniated in lumbar spine. Despite advances neuroimaging modification methods techniques, this pathology is rarely diagnosed preoperatively. Its involves considerable technical difficulties associated high rate revision operations. study material included abstracts articles from PubMed database published Journal Bone Joint...

10.14531/ss2016.4.73-77 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2016-11-28

The concept of “tandem stenosis” comprises combination degenerative stenosis in both cervical and lumbar spine. At the moment, there is no consistent approach to surgical procedures this group patients, as well research-ers do not pay much attention their papers sequence stage-by-stage analysis combined procedures. aim research was analyze results staging decompression/stabilization interventions treatment patients with tandem We performed a retrospective prospectively collected 46patients...

10.12737/22974 article EN cc-by Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук 2016-11-28

Objective. To assess the efficacy of decompression, correction, and stabilization lumbar spine deformity using minimally invasive techniques in patients with degenerative scoliosis. Material Methods. A retrospective controlled two-center study included 62 who underwent surgery for clinical manifestations scoliosis spinal canal. Results. Average Oswestry index before was 69.69 %, after it decreased to 33.00 % ranged between 14 50 %. magnitude lordosis 39.2°; average rate correction - 56.53 %;...

10.14531/ss2014.4.49-56 article EN cc-by Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 2018-01-24
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