Nasser Hadal Alotaibi

ORCID: 0000-0002-2604-8075
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Synthesis and biological activity
  • Pharmaceutical Practices and Patient Outcomes
  • Vaccine Coverage and Hesitancy
  • Natural product bioactivities and synthesis
  • Computational Drug Discovery Methods
  • Antibiotic Use and Resistance
  • Pharmacological Effects of Natural Compounds
  • COVID-19 and Mental Health
  • Medication Adherence and Compliance
  • Essential Oils and Antimicrobial Activity
  • Synthesis and Biological Evaluation
  • Misinformation and Its Impacts
  • Drug Solubulity and Delivery Systems
  • Liver Disease Diagnosis and Treatment
  • Rheumatoid Arthritis Research and Therapies
  • Ocular Surface and Contact Lens
  • Natural Antidiabetic Agents Studies
  • Dialysis and Renal Disease Management
  • Diet and metabolism studies
  • Biological Activity of Diterpenoids and Biflavonoids
  • Advancements in Transdermal Drug Delivery
  • Berberine and alkaloids research
  • Analytical Chemistry and Chromatography

Jouf University
2019-2025

Imam Abdulrahman Bin Faisal University
2025

King Saud University
2024

Lahore College for Women University
2022

King Fahd Military Medical Complex
2021

University of Sargodha
2020

University of the Punjab
2020

University of Lahore
2020

University of Strathclyde
2019

King Abdulaziz Medical City
2019

Immediately after declaring COVID-19 as a pandemic, numerous wild conspiracy theories sprouted through social media. Pakistan is quite vulnerable to such narratives and has experienced failures of polio vaccination programs because claims. Recently, two well-known political figures raised against vaccines in Pakistan, stating that grand illusion Muslim countries. This theory much discussed the local community, supporting vaccine hesitancy. We urge healthcare authorities take necessary...

10.4269/ajtmh.20-0654 article EN other-oa American Journal of Tropical Medicine and Hygiene 2020-06-23

Treatment options for the management of breast cancer are still inadequate. This inadequacy is attributed to lack effective targeted medications, often resulting in recurrence metastatic disorders. Cumulative evidence suggests that epidermal growth factor receptor (EGFR-TK) and cyclin-dependent kinases-9 (CDK-9) overexpression correlates with worse overall survival patients. Pyranopyrazole pyrazolone privileged development anticancer agents. Inspired by this proven scientific fact, we report...

10.1080/07391102.2023.2167000 article EN Journal of Biomolecular Structure and Dynamics 2023-01-20

Diabetic (type-2) is a metabolic disease characterized by increased blood glucose level from the normal level. In present study, apigenin (AG) loaded lipid vesicles (bilosomes: BIL) was prepared, optimized and evaluated for oral therapeutic efficacy.AG-BIL prepared thin-film evaporation method using cholesterol, span 60 sodium deoxycholate. The formulation 3-factor 3-level Box-Behnken design particle size, entrapment efficiency drug release as response. selected further ex-vivo permeation,...

10.1016/j.jsps.2021.02.003 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2021-02-23

Background: Nowadays, recycling agricultural waste is of the utmost importance in world for production valuable bioactive compounds and environmental protection. Olive leaf have a significant potential impact on pharmaceutical industry. These possess remarkable biological characteristics, including antimicrobial, antiviral, anti-inflammatory, hypoglycemic, antioxidant properties. Methods: The present study demonstrates green synthetic approach fabrication nickel oxide nanoparticles...

10.2147/ijn.s443965 article EN cc-by-nc International Journal of Nanomedicine 2024-02-01

Purpose: The present study was designed to the gentamycin (GTM)-loaded stimulus-responsive chitosan nanoparticles treat bacterial conjunctivitis. Methods: GTM-loaded (GTM-CHNPs) were prepared by ionotropic gelation method and further optimized 3-factor 3-level Box–Behnken design. Chitosan (A), sodium tripolyphosphate (B), stirring speed (C) selected as independent variables. Their effects observed on particle size (PS Y1), entrapment efficiency (EE Y2), loading capacity (LC Y3). Results:...

10.2147/ijn.s254763 article EN cc-by-nc International Journal of Nanomedicine 2020-06-01

Nanotechnology is emerging as a new technology with encouraging innovations. Global antibiotic use has grown enormously, resistance increasing by about 80 percent. In view of this alarming situation, intensive research been carried out into biogenic nanoparticles and their antibacterial, antifungal, antitumor activities. Many methods are available to enhance stability dispersion via peroration conjugate polymer, such chitosan, other bioactive natural products. Two marine fungi were isolated...

10.3390/antibiotics11050668 article EN cc-by Antibiotics 2022-05-16

Type 2 Diabetes mellitus is a major public health concern with an alarming global growth rate. According to the World Health Organization (WHO), Saudi Arabia ranks seventh in world and second Middle East for largest estimated burden of diabetic cases. Evidence shows that pharmacist-led care programs can be beneficial effective treatment diabetes mellitus. Current study was aimed evaluate impact Pharmacist-Based Diabetic Intervention (PDIM) patients on knowledge disease, adherence medications...

10.3390/ijerph191610060 article EN International Journal of Environmental Research and Public Health 2022-08-15

Background Influenza vaccine hesitancy is a significant threat to global maneuvers for reducing the burden of seasonal and pandemic influenza. This study estimated uptake, barriers, willingness influenza vaccines among university students in Saudi Arabia. Methods A cross-sectional survey was conducted health science (HS) non-health (NHS) students. 31-item questionnaire used ascertain vaccination rate, flu vaccine. Results included 790 (mean age: 21.40 ± 1.94 years), 246 (31.1%) from HS 544...

10.7717/peerj.13959 article EN cc-by PeerJ 2022-09-28

With an increase in the global burden of cancer-related deaths, quest for developing new therapeutic solutions has taken momentum. In this regard, idea using cancer vaccines came to existence approximately 30 years ago, where gene therapy interventions have shown significant improvement outcomes against several types cancers. Cancer usually encounter a number challenges with limited targeting ability tumors. Nanocarriers been studied as technological innovation tumor therapeutics. This...

10.2217/nnm-2020-0046 article EN Nanomedicine 2020-05-15

Background Evaluation of patients`satisfaction towards pharmacy services is utmost importance to ensure the quality care. It helps in identifying domains requiring improvements provide high provision enhanced pharmaceutical The current study aims ascertain extent satisfaction among patients attending outpatient pharmacies Kingdom Saudi Arabia. Methods A hospital-based cross-sectional involving 746 various public hospitals was conducted from 01 January 15 February 2020. Information on...

10.1371/journal.pone.0247912 article EN cc-by PLoS ONE 2021-04-01

Vaccination protects people from serious illness and associated complications. Conspiracy theories misinformation on vaccines have been rampant during the COVID-19 pandemic are considered significant drivers of vaccine hesitancy. Since hesitancy can undermine efforts to immunize population against interferes with vaccination rate, this study aimed ascertain COVID-19-vaccine-related conspiracy beliefs, hesitancy, views regarding mandates, willingness pay for among general population. A...

10.3390/vaccines10111866 article EN cc-by Vaccines 2022-11-04

Orthodontic-induced mouth ulcers are a common complication arising from mechanical irritation and increased plaque accumulation during treatment. These painful lesions significantly impact the comfort compliance of patients undergoing orthodontic care. Various factors contribute to their development, including appliance design, oral hygiene, dietary habits, stress, systemic conditions like nutritional deficiencies. Effective prevention management strategies essential mitigate these effects...

10.18203/2394-6040.ijcmph20250041 article EN International Journal of Community Medicine and Public Health 2025-01-22

The continuing growth of bacterial resistance makes the top challenge for healthcare system especially in bone-infections treatment. Current estimates reveal that 2050 death ratio caused by infections can be higher than cancer. aim this study is to provide an alternative currently available bone-infection treatments. Here we designed mesoporous hydroxyapatite nanocarriers functionalized with citrate (Ctr-mpHANCs). Amoxicillin (AMX) used as a model drug load Ctr-mpHANCs, and loading was more...

10.3390/pharmaceutics14050975 article EN cc-by Pharmaceutics 2022-04-30
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