A5050371353- Plant Toxicity and Pharmacological Properties
- Phytochemistry and biological activity of medicinal plants
- Phytochemistry Medicinal Plant Applications
- Cassava research and cyanide
- Pesticide Exposure and Toxicity
- Prenatal Substance Exposure Effects
- Plant-based Medicinal Research
- Natural product bioactivities and synthesis
- Metabolism and Genetic Disorders
- Carbohydrate Chemistry and Synthesis
- Toxin Mechanisms and Immunotoxins
- Drug-Induced Hepatotoxicity and Protection
- Botanical Research and Chemistry
- Birth, Development, and Health
- Ginkgo biloba and Cashew Applications
- Phytochemistry and Biological Activities
- Antibiotics Pharmacokinetics and Efficacy
- Folate and B Vitamins Research
- Animal Nutrition and Physiology
- Bioactive Compounds and Antitumor Agents
- Ginseng Biological Effects and Applications
- Rabbits: Nutrition, Reproduction, Health
- Pharmaceutical and Antibiotic Environmental Impacts
- Agricultural and Food Sciences
- Public Health in Brazil
Universidade de São Paulo
2015-2024
University of Houston
2017
Fundação de Estudo e Pesquisa em Medicina Veterinária e Zootecnia
2015
Centro Universitário FIEO
2013
Universidade Brasil
2007-2012
Universidade Cidade de São Paulo
2008
Hokuriku University
2003
The aim of this study was to assess the toxic effects zearalenone (ZEA) on immune function. Ovariectomised rats were treated daily by gavage with 3.0 mg/kg ZEA for 28 days. Body weight gain, food consumption, haemotological parameters, lymphoid organs, and their cellularities evaluated. Moreover, acquired responses macrophage activity also assessed. promoted reduction in body which is not fully explained diminished consumption. Despite no effect haematological caused thymic atrophy...
Natural intoxication of livestock by the ingestion Ipomoea carnea (Convolvulaceae) sometimes occurs in tropical regions world. Polyhydroxylated alkaloids were isolated from leaves, flowers, and seeds poisonous plant characterized. Chromatographic separation leaf extract resulted isolation swainsonine (1), 2-epi-lentiginosine (2), calystegines B1 (3), B2 (4), B3 (5), C1 (6), N-methyl-trans-4-hydroxy-l-proline (7). The contents 1 fresh leaves flowers 0.0029 0.0028%, respectively, whereas 1, 3,...
A fast and simple method was developed to determine pyrrolizidine alkaloids (PAs) in honey using liquid chromatography tandem mass spectrometry (LC- MS/MS) with electrospray ionization (ESI). An efficient extraction procedure carried out by simply diluting water, without the need of any additional clean-up steps. full validation performed according Commission Decision 2002/657/EC. The linear 050 μg kg−1 range presented satisfactory intra-day inter-day precision relative standard deviations...
The aim of this trial was to implement a method obtain tool for analyses tramadol and the main metabolite, o ‐desmethyltramadol (M1), in goat's plasma, evaluate pharmacokinetics these substances following intravenous (i.v.) oral (p.o.) administration female goats. M1 were examined i.v. or p.o. six goats (2 mg/kg). Average retention time 5.13 min 2.42 M1. calculated parameters half‐life, volume distribution total body clearance 0.94 ± 0.34 h, 2.48 0.58 L/kg 2.18 0.23 L/kg/h 2 mg/kg HCl...
Pteridium aquilinum (bracken fern) is one of the most common plants. Epidemiological studies have revealed a higher risk certain types cancers (i.e., esophageal, gastric) in people who consume bracken fern directly (as crosiers or rhizomes) indirectly through consumption milk from livestock that fed on plant. In animals, evidence exists regarding associations between chronic intoxication, papilloma virus infection, and development carcinomas. While it possible some carcinogens could be...
Casearia sylvestris S.w (Salicaceae) is catalogued by the Brazilian Unified Health System as a plant of interest for population with purpose treating inflammatory disorders, such pain and gastrointestinal disorders based on folk use some literature about efficacy; however, no toxicological studies concerned safety extract fluid this have been reported.The present study was carried out to evaluate acute subchronic toxicity hydroethanolic (FE) obtained from leaves C. in Wistar rats.In test...
We have previously shown that bracken fern (Pteridium aquilinum) has immunomodulatory effects on mouse natural killer (NK) cells by reducing cytotoxicity. Alternatively, it been demonstrated selenium can enhance NK cell activity. Therefore, the aims of present study were to evaluate if ptaquiloside, main toxic component found in P. aquilinum, is responsible for immunotoxic observed mice, and supplementation could prevent or even reverse these effects. Male C57BL/6 mice administered aquilinum...