Abstract: Total water extract, ethyl acetate, and aqueous fractions from the leaves of Artocarpus heterophyllus were evaluated for phenolic content, antioxidant, antibacterial activities against some foodborne pathogens such as E. coli , Listeria monocytogenes Salmonella typhimurium enterica Bacillus cereus Enterococcus faecalis Staphylococcus aureus . The minimum inhibitory concentration (MICs) extract determined by agar dilution method ranged 221.9 μg/mL acetate fraction to 488.1 total...

Different parts including the latex of Ficus racemosa L. has been used as a medicine for wound healing in Ayurveda and indigenous system Sri Lanka. This plant evaluated its potential using animal models. The aim this study was to obtain an insight into process identify active substance/s present F. bark scratch assay (SWA) in-vitro method.Stem extracts were on Baby Hamster Kidney (BHK 21) Madin-Darby Canine (MDCK) cell lines Kirby Bauer disc diffusion common bacteria fungi migration...

Ayurvedic and traditional medical practitioners of Sri Lanka use the decoction immature inflorescence Cocos nucifera L. (IC) variety aurantiaca for treatment menorrhagia. The progestogenic effect ethyl acetate soluble proanthocyanidins (EASPA) IC in female rats at a dose 3.5 mg/kg body weight has been reported. Acute subacute toxicity studies EASPA carried out using Wistar according to Organization Economic Co-operation Development (OECD) guidelines 423 407, respectively, are reported...

Nothapodytes nimmoniana (Icacinaceae) is a rich source of Camptothecin (CPT), an anti-cancer prodrug. Efficient extraction CPT from various plant parts crucial for better recovery this pre-drug.To investigate the distribution in and to compare methods on yield evaluate how cellular localisation affects efficiency methods.Transverse sections were observed under ultraviolet (UV)-fluorescence microscope fluorescence that molecule emits when exposed UV radiation. Dried extracted using 90%...

Out-of-plane bisdicarbonylrhodium complexes of etioporphyrin I and a monoazaporphyrin undergo oxidative addition reactions with variety substrates RX [R = aryl, acyl, arylcarbonyl, alkoxycarbonyl, ethoxycarbonylmethyl, R′COCH2, or I; X H Br (usually) CH2COMe (in certain cases)]. One rhodium atom is detached from the macrocycle. The remaining R–RhIII species captured by central porphyrin cavity, retaining R, but loss X, to give R–RhIII-etioporphyrin -monoazaporphyrin. Several new types...

An endophytic fungus producing camptothecin (CPT) was isolated from the leaf of Nothapodytes nimmoniana (Sri Lanka), and culture conditions were optimised to enhance yield CPT. The TLC, HPLC-PDA, LC-MS/MS spectroscopic data used identify quantify Solvent extraction (chloroform: methanol 4:1 v/v) submerged cultures in Sabouraud Dextrose Broth (SDB) detected CPT mycelial extract but not broth. (KX212080) closely related Diaporthe guangxiensis (MK335772) with 99% sequence similarity, thus...

The reaction of di-µ-chloro-bis(dicarbonylrhodium) with N-methylcorroles gives stable out-of-plane complexes involving adjacent nitrogen atoms. An analogous complex is formed by a 21,24-dioxacorrole. N-22-methylcorrole undergoes thermal equilibration an isomeric non-adjacent X-ray crystal structures two N-methylcorrolebis[dicarbonylrhodium(I)] are reported. Reaction N-methyletioporphyrin I rise to methylrhodium(III)–etioporphyrin and similar was observed N-methylazaporphyrins. In the...

The reaction of polypyrrole macrocycles with di-µ-chloro-bisdicarbonylrhodium gives rise to out-of-plane mono-(with corroles and thiaphlorins) or bis-dicarbonylrhodium (with porphyrins azaporphyrins) complexes, depending on the number imino- amino-groups present in central macrocycle cavity. tautomeric oxophlorins give both mono- complexes cobalt(III) complex aetio-oxophlorin is shown by n.m.r. exist as aromatic zwitterion benzene solution. dicarbonylrhodium(I) undergo oxidative addition...

Abstract Attempts have been made to predict the most feasible end‐use for palmyrah fruit pulp (PFP), which is still largely regarded as a waste product. Correlation of with flabelliferin profile logical but practically difficult, it has found that morphology and colour (carotenoid content) do not correlate each other, neither predictive value profile. It appears some varieties are sweet can be used products such jams cordials. A few very bitter PFPs de‐bittered cheap commercial enzyme...

Platostoma menthoides (L.) A. J. Paton (Syn: Geniosporum prostratum (L) Benth. tenuiflorum) is an aromatic annual herb found in India and Sri Lanka belonging to the family Lamiaceae. Hydrodistillation of plant collected from North Central province Lanka, yielded 0. 5% (v/w) a light yellow colored fragrant oil. The oil was analyzed by GC-FID GC-MS. A total 74 components accounting for 85.01 % were identified comparison their mass spectra with those NIST WILEY libraries retention indices...

A. M. Abeysekera, R. Grigg, J. Trocha-Grimshaw and V. Viswanatha, Chem. Soc., Commun., 1976, 227 DOI: 10.1039/C39760000227

Abstract Nimba arishta is an ayurvedic drug obtained by fermentation of a decoction Azadirachta indica bark to which sugar and kalka have been added. Kalkas consist various plant materials including flowers Woodfordia fruticosa . The effects the preparation process on immunomodulatory properties were investigated means model systems. On basis traditional applications arista in Sri Lanka, complement activity functioning granulocytes selected as relevant immunological parameters our studies....

Chemical investigation of the essential oil obtained from heartwood Erythroxylum monogynum Roxb. yielded three beyerene type diterpenoids ent-beyer-15-ene (1), ent-beyer-15-en-19-ol (erythroxylol A) (2) and ent-beyer-15-en-19-al (3). Ent-beyer-15-en-19-al (3) was found to be unstable at room temperature, giving rise hitherto unknown 15,16-epoxy-ent-beyeran-19-oic acid (4). This conversion involves auto-oxidation a C-4 axial aldehyde group an diterpenoid with concurrent epoxidation C-15...

Link Samahan® (LS) is a standardized modern formulation of polyherbal preparation used in the indigenous system medicine Sri Lanka.Evaluation immunostimulatory activity LS and molecular mechanisms that modulate humoral immune response.Immunostimulatory was tested rats following oral administration on days 1-5 15-19 immunization with bovine serum albumin (BSA) day 1 15. Anti-BSA IgM IgG response treated LS, water sugar (as controls) were compared 0-35, using ELISA. The expression...

Meso-azoporhyrins exist in the meso-imino tautomeric form. Attempts to trap or generate meso-amino tautomer were unsuccessful. STO-3G and CNDO/2 calculations indicate lie > 22 kcal mol–1 below both meso-monoaza- meso-tetra-aza-porphyrins. The crystal structure of a meso-monoazaocta-alkylporphyrinatocobalt(II) complex is reported.