A5101603720- Cardiac Imaging and Diagnostics
- Advanced Image Processing Techniques
- Cardiovascular Function and Risk Factors
- Image and Signal Denoising Methods
- Formal Methods in Verification
- Cardiac electrophysiology and arrhythmias
- Advanced MRI Techniques and Applications
- Image Processing Techniques and Applications
- Renal cell carcinoma treatment
- Medical Imaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- HER2/EGFR in Cancer Research
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Real-Time Systems Scheduling
- Advanced Vision and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Rough Sets and Fuzzy Logic
- Logic, programming, and type systems
- Data Mining Algorithms and Applications
- Software Testing and Debugging Techniques
- Urologic and reproductive health conditions
First Affiliated Hospital of Anhui Medical University
2023-2025
Shanghai Public Health Clinical Center
2025
Fifth Affiliated Hospital of Zhengzhou University
2023-2025
Zhengzhou University
2025
First Hospital of China Medical University
2017-2024
China Medical University
2017-2024
Anhui Medical University
2015-2024
Lu'an First People's Hospital
2024
Zhejiang University
2023-2024
Zhejiang University of Science and Technology
2023-2024
Magnetic resonance imaging (MRI) can present multicontrast images of the same anatomical structures, enabling multi-contrast super-resolution (SR) techniques. Compared with SR reconstruction using a single-contrast, is promising to yield higher quality by leveraging diverse yet complementary information embedded in different modalities. However, existing methods still have two shortcomings: (1) they neglect that features at scales contain details and hence lack effective mechanisms match...
Deep learning based generative adversarial networks (GAN) can effectively perform image reconstruction with under-sampled MR data. In general, a large number of training samples are required to improve the performance certain model. However, in real clinical applications, it is difficult obtain tens thousands raw patient data train model since saving k-space not routine flow. Therefore, enhancing generalizability network on small urgently needed. this study, three novel applications were...
Abstract Background The purpose of this study was to investigate the correlation between novel anthropometric indices, specifically body shape index (ABSI) and roundness (BRI), prevalence kidney stone disease (KSD) within general population United States (U.S.). Methods This employed a cross-sectional analysis participants in National Health Nutrition Examination Survey from 2007 2020. Various statistical methods, including multivariable logistic regression analysis, restricted cubic spline...
The hypothesis that marrow-derived cells, and specifically proinflammatory proteins in those play a critical role the development of diabetes-induced retinopathy tactile allodynia was investigated. Abnormalities characteristic early stages were measured chimeric mice lacking inducible nitric oxide synthase (iNOS) or poly(ADP-ribosyl) polymerase (PARP1) only their cells. Diabetes-induced capillary degeneration, changes, superoxide production retina inhibited diabetic animals which iNOS PARP1...
Magnetic resonance imaging (MRI) possesses the unique versatility to acquire images under a diverse array of distinct tissue contrasts, which makes multicontrast super-resolution (SR) techniques possible and needful. Compared with single-contrast MRI SR, SR is expected produce higher quality by exploiting variety complementary information embedded in different contrasts. However, existing approaches still have two shortcomings: 1) most them are convolution-based methods and, hence, weak...
Abstract Introduction Previous RC48 (Disitamab Vedotin) studies established that the safety and efficacy of RC48‐antibody–drug conjugate (ADC), either alone or combined with toripalimab, for metastatic urothelial carcinoma (mUC) patients exhibiting human epidermal growth factor receptor 2 (HER2)‐positive even HER2‐negative status after standard chemotherapy failure. Methods With locally advanced (la/mUC), who received RC48‐ADC monotherapy a combination programmed cell death protein 1 (PD‐1)...
Guanylate‑binding protein 2 (GBP2) has been widely studied in cancer, however, its potential role clear cell renal carcinoma (ccRCC) is not fully elucidated. The present study aimed to explore the effect of GBP2 on tumor progression and possible underlying molecular mechanisms ccRCC. Cancer Genome Atlas, Gene Expression Omnibus, Cell Line Encyclopedia databases, several bioinformatics analysis tools, such as Profiling Interactive Analysis 2, Kaplan‑Meier plotter, UALCAN, LinkedOmics,...
Recently, several methods have explored the potential of multi-contrast magnetic resonance imaging (MRI) super-resolution (SR) and obtain results superior to single-contrast SR methods. However, existing approaches still two shortcomings: (1) They can only address fixed integer upsampling scales, such as 2×, 3×, 4×, which require training storing corresponding model separately for each scale in clinic. (2) lack direct interaction among different windows they adopt square window (e.g., 8×8)...
Understanding the early pathogenesis of DR may uncover new therapeutic targets to prevent or slow progression this sight-threatening disorder. We investigated role leukocyte-mediated generation LTs in regulation retinal capillary degeneration and inflammation diabetic mouse. generated (1) chimeric mice that lacked ability generate by transplanting 5LO-/- bone marrow cells into ND.WT SD.WT (2) "control" WT mice. Retinas from with demonstrated same extent as retinas diabetic, nonchimeric In...
We set out to study the key effectors of resistance and sensitivity ErbB2 tyrosine kinase inhibitors, such as lapatinib in ErbB2-positive breast lung cancers. A cell-based vitro site-directed mutagenesis model identified several mutations, including gatekeeper mutation ErbB2-T798I, mediating resistance. ErbB2-T798I engineered cell models indeed show but remain sensitive irreversible EGFR/ErbB2 inhibitor, PD168393, suggestive potential alternative treatment strategies overcome Gene expression...
Magnetic resonance imaging (MRI) is an important medical modality, but its acquisition speed quite slow due to the physiological limitations. Recently, super-resolution methods have shown excellent performance in accelerating MRI. In some circumstances, it difficult obtain high-resolution images even with prolonged scan time. Therefore, we proposed a novel method that uses generative adversarial network cyclic loss and attention mechanism generate MR from low-resolution by upsampling factors...
Compressed sensing (CS) can speed up the magnetic resonance imaging (MRI) process and reconstruct high-quality images from under-sampled k-space data. However, traditional CS-MRI suffers slow iterations artifacts caused by noise when acceleration factor is high. Currently, deep learning has been introduced to address these issues. Although some improvements have achieved, reconstruction problem under high under-sampling rates not solved. Thus, our study proposed a novel method called...
Virtual try-on methods based on diffusion models achieve realistic effects. They use an extra reference network or additional image encoder to process multiple conditional inputs, which results in high training costs. Besides, they require more than 25 inference steps, bringing a long time. In this work, with the development of transformer (DiT), we rethink necessity encoder, then propose MC-VTON, enabling DiT integrate minimal inputs by utilizing its intrinsic backbone. Compared existing...
Metallothioneins (MTs) are a class of cysteine-rich proteins that actively participate in the cellular defense against free radicals. However, owing to high heterogeneity among different MTs, comprehensive investigations needed determine biological activities and distribution patterns each MT tissues. In present study, ectopic expression MT1H significantly inhibited proliferation gastric cancer cells. Mechanistically, was transported into nucleus regulated key genes involved nutrient...