A5090033381- Hematopoietic Stem Cell Transplantation
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Mesenchymal stem cell research
- T-cell and B-cell Immunology
- Corneal Surgery and Treatments
- Lung Cancer Treatments and Mutations
- Corneal surgery and disorders
- Acute Myeloid Leukemia Research
- MicroRNA in disease regulation
- Ocular Surface and Contact Lens
- Nanoparticle-Based Drug Delivery
- Virus-based gene therapy research
- Pharmacological Effects of Natural Compounds
- Acute Lymphoblastic Leukemia research
- Diabetes and associated disorders
- Fire dynamics and safety research
- Monoclonal and Polyclonal Antibodies Research
- Radiopharmaceutical Chemistry and Applications
- Gastrointestinal motility and disorders
- COVID-19 Clinical Research Studies
- Medical Research and Treatments
- Combustion and Detonation Processes
- Immune cells in cancer
- Histone Deacetylase Inhibitors Research
Xinqiao Hospital
2018-2025
Army Medical University
2018-2025
Chongqing Medical University
2025
Second Affiliated Hospital of Chongqing Medical University
2025
Dalian Medical University
2025
Beijing Luhe Hospital Affiliated to Capital Medical University
2025
Shandong First Medical University
2020-2024
Jinan Central Hospital
2013-2024
Anhui University of Traditional Chinese Medicine
2024
Hunan University
2024
Significance Conventional electroencephalogram (EEG) recording systems, particularly the hardware components that form physical interfaces to head, have inherent drawbacks limit widespread use of continuous EEG measurements for medical diagnostics, sleep monitoring, and cognitive control. Here we introduce soft electronic constructs designed intimately conform complex surface topology auricle mastoid, provide long-term, high-fidelity data. Systematic studies reveal key aspects extreme levels...
Non‐invasive, biomedical devices have the potential to provide important, quantitative data for assessment of skin diseases and wound healing. Traditional methods either rely on qualitative visual tactile judgments a professional and/or obtained using instrumentation with forms that do not readily allow intimate integration sensitive near site. Here, an electronic sensor platform can softly reversibly laminate perilesionally at wounds highly accurate, relevance management surgical healing is...
Background: Elevated level of D-dimer was reported in some patients with COVID-19 pneumonia on admission, especially severe However, it wa
The hypothesis that marrow-derived cells, and specifically proinflammatory proteins in those play a critical role the development of diabetes-induced retinopathy tactile allodynia was investigated. Abnormalities characteristic early stages were measured chimeric mice lacking inducible nitric oxide synthase (iNOS) or poly(ADP-ribosyl) polymerase (PARP1) only their cells. Diabetes-induced capillary degeneration, changes, superoxide production retina inhibited diabetic animals which iNOS PARP1...
Abstract Safety and efficacy of allogeneic anti-CD19 chimeric antigen receptor T cells (CAR-T cells) in persons with CD19-positive B-cell acute lymphoblastic leukemia (B-ALL) relapsing after an allotransplant remain unclear. Forty-three subjects B-ALL post received CAR-T were analyzed. 34 (79%; 95% confidence interval [CI]: 66, 92%) achieved complete histological remission (CR). Cytokine release syndrome (CRS) occurred 38 (88%; 78, 98%) was ≥grade-3 7. Two died from multiorgan failure CRS....
The epidemic of novel coronavirus disease was first reported in China late December 2019 and brought under control after some 2 months China. However, it has become a global pandemic, the number cases deaths continues to increase outside We describe emergence detail 100 days China's response as phase 1 containment strategy followed by containment, briefly highlight areas focus for future. Specific, simple, pragmatic strategies used risk assessment, prioritization, deployment resources are...
Chemotherapy resistance and the tumor immune microenvironment are dual reasons for poor therapeutic efficacy of treating acute myeloid leukemia (AML), causing suboptimal clinical outcomes high relapse rates. Activation stimulator interferon genes (STING) pathway based on innate immunity can effectively improve antitumor immunity. However, traditional STING agonists limited due to their easy degradation difficult membrane transport. Here, a bioinspired nanomedicine synergizing chemo-...
Methane/air explosion is one of the common hazards in process and mining industries. In this study, methane propagation studied, two-dimensional configuration considered. The gas phase equations are solved using an OpenFOAM code for compressible reacting flow, EXiFOAM. effects low blockage ratio (LBR) obstacles investigated. results show that flame speed, structure, shock wave propagation, flow considerably affected by LBR obstacles. Specifically, speed first increases then decreases. As...
Background Atherosclerosis is a chronic inflammatory disease mediated by immune cells. Th22 cells are CD4+ T that secret IL-22 but not IL-17 or IFN-γ and implicated in the pathogenesis of disease. The roles pathophysiologic procedures acute coronary syndrome (ACS) remain unclear. purpose this study to investigate profile Th22, Th17 Th17/Th1 ACS patients, including unstable angina (UA) myocardial infarction (AMI) patients. Design Methods In study, 26 AMI 16 UA stable (SA) patients healthy...
We set out to study the key effectors of resistance and sensitivity ErbB2 tyrosine kinase inhibitors, such as lapatinib in ErbB2-positive breast lung cancers. A cell-based vitro site-directed mutagenesis model identified several mutations, including gatekeeper mutation ErbB2-T798I, mediating resistance. ErbB2-T798I engineered cell models indeed show but remain sensitive irreversible EGFR/ErbB2 inhibitor, PD168393, suggestive potential alternative treatment strategies overcome Gene expression...