A5083094483- Polysaccharides and Plant Cell Walls
- Legume Nitrogen Fixing Symbiosis
- Analytical Chemistry and Chromatography
- Enzyme Production and Characterization
- Microbial Metabolites in Food Biotechnology
- Microtubule and mitosis dynamics
- Proteoglycans and glycosaminoglycans research
- Plant biochemistry and biosynthesis
- Drug Solubulity and Delivery Systems
- Polysaccharides Composition and Applications
- Chemical Synthesis and Analysis
- Animal Ecology and Behavior Studies
- Forest Insect Ecology and Management
- Innovative Microfluidic and Catalytic Techniques Innovation
- Carbohydrate Chemistry and Synthesis
- Grouting, Rheology, and Soil Mechanics
- DNA and Nucleic Acid Chemistry
- Biological Stains and Phytochemicals
- Microfluidic and Capillary Electrophoresis Applications
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Polyamine Metabolism and Applications
- Clay minerals and soil interactions
- Probiotics and Fermented Foods
- Insect Pest Control Strategies
Centre National de la Recherche Scientifique
2001-2024
Université Grenoble Alpes
2003-2024
Département de Pharmacochimie Moléculaire
2003-2023
Département de Chimie Moléculaire
2003-2023
Université Joseph Fourier
1998-2011
CEA Grenoble
2003-2004
Institut de Biologie Structurale
2003-2004
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2003-2004
Centre de Recherches sur les Macromolécules Végétales
2003-2004
The strain MWAP71 of Burkholderia caribensis produces a branched charged exopolysaccharide (EPS) that is responsible for soil aggregation. Understanding the conformational properties isolated polysaccharide prerequisite proper investigation interactions between and at atomic level. aim this study first to have an overall view flexibility backbone then ascertain role played by side groups in main chain. Conformational analysis each oligomeric segment has been performed means adiabatic mapping...
Interferons are cytokines that play a complex role in the resistance of mammalian hosts to pathogens. IFNγ (interferon-γ) is secreted by activated T-cells and natural killer cells. involved wide range physiological processes, including antiviral activity, immune response, cell proliferation apoptosis, as well stimulation repression variety genes. activity modulated binding its C-terminal domain HS (heparan sulphate), glycosaminoglycan found extracellular matrix at surface. In present study,...
Nanoparticles of amphiphilic α-, β-, and γ-cyclodextrins were obtained by formulation cyclodextrins enzymatically transesterified with vinyl decanoate. The product this synthesis is a mixture bioesterified various degrees substitution (DS) presenting for same DS different regio-isomers. In first step, the efficiency MALDI-TOF procedure to characterize average molecular weight derivative bulk was demonstrated comparing results those from complementary NMR HPLC techniques. second...
Abstract The synthesis of new β‐cyclodextrin dimers linked through their primary faces by different glycerol‐like moieties click chemistry is described. unusual behaviour these cyclodextrin–glycerol in aqueous solution has been studied NMR spectroscopy. We show that, depending on the length linking arm between two cyclodextrins, could adopt very conformations water: symmetrical or pseudo[1]rotaxane‐like structures one D ‐glucopyranose unit tumbling β‐cyclodextrin.
Mistletoe (Viscum album L.) is used in German-speaking European countries the field of integrative oncology linking conventional and complementary medicine therapies to improve quality life. Various companies sell extracts, fermented or not, for injection by subcutaneous intra-tumoral route with a regulatory status anthroposophic medicinal products (European Medicinal Agency (EMA) assessment status). These as well anthroposophical physicians argue that complex matrices composed many...
In this paper, a new ligand-exchange -MEKC mode, based on the design of unique lipohilic species (4'-octadecylneamine derivative), which served both as micelle-forming surfactant (by its hydrophobic part) and central ion-complexing ligand hydrophilic is described. The CMC used lipophilic neamine derivative was first determined by surface tension measurements. Subsequent NMR experiments were performed in order to investigate Cu(II) binding properties micellar phase. enantioseparation...
Abstract Aptamers constitute an emerging class of molecules designed and selected to recognize any given target that ranges from small compounds large biomolecules, even cells. However, the underlying physicochemical principles govern ligand‐binding process still have be clarified. A major issue when dealing with short oligonucleotides is their intrinsic flexibility renders active conformation highly sensitive experimental conditions. To overcome this problem determine best parameters,...
F-STOP is a microtubule-associated protein that stabilizes microtubules in calmodulin (CaM)-dependent manner. All members of the stable tubule only polypeptide (STOP) family have central domain contains nearly identical multiple repeats, and CaM binding motif present copies within this domain. We here an analysis interaction find it highly unusual nature. For work, we synthesized two model peptides single STOP repeat analyzed their to by fluorescence, circular dichroism, infrared NMR...
Secondary metabolites are essential for plant survival and reproduction. Wild undomesticated tropical plants expected to harbor highly diverse metabolomes. We investigated the metabolomic diversity of two morphologically similar trees Africa, Erythrophleum suaveolens E. ivorense, known particular secondary named cassaine-type diterpenoids. To assess how metabolome varies between within species, we sampled leaves from individuals different geographic origins but grown seeds in a common garden...
The recent biological invasion of box tree moth Cydalima perspectalis on Buxus trees has a major impact European boxwood stands through severe defoliation. This can hinder further regrowth and threaten survival populations. In mesocosm approach controlled larval density over 2-month period, responses B. sempervirens essential specialized metabolites were characterized using metabolomics, combining