A5055597962- Analytical Chemistry and Chromatography
- Glioma Diagnosis and Treatment
- Analytical Methods in Pharmaceuticals
- Brain Metastases and Treatment
- Protein purification and stability
- COVID-19 Clinical Research Studies
- Advanced Chemical Sensor Technologies
- Occupational and environmental lung diseases
- Cancer Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- Cancer, Hypoxia, and Metabolism
- Wireless Body Area Networks
- Sleep and Wakefulness Research
- Viral gastroenteritis research and epidemiology
- Neurological disorders and treatments
- Epilepsy research and treatment
Istituto Superiore di Sanità
2021-2023
Sapienza University of Rome
2020-2022
Istituto Neurologico Mediterraneo
2022
The increasing use of information technology in the discovery new molecular entities encourages modern molecular-modeling tools to help teach important concepts drug design chemistry and pharmacy undergraduate students. In particular, statistical models such as quantitative structure–activity relationships (QSAR)—often its 3D QSAR variant—are commonly used development optimization a leading compound. We describe how these methods can be taught learned by means free open-source web...
Antibodies targeting Receptor Binding Domain (RBD) of SARS-CoV-2 have been suggested to account for the majority neutralizing activity in COVID-19 convalescent sera and several antibodies (nAbs) isolated, characterized proposed as emergency therapeutics form monoclonal (mAbs). However, variants are rapidly spreading worldwide from sites initial identification. The concern (VOC) B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) B.1.167.2 (Delta) showed mutations spike protein potentially able...
Abstract Background to analyze GBM recurrence pattern after standard chemoradiotherapy according different target volume delineations. We hypothesized that reduced margins may result in similar of failure. Material and Methods 207 patients with who recurred chemoradiation were evaluated. According the Advisory Committee for Radiation Oncology Practice (ACROP) committee European Organisation Research Treatment Cancer (EORTC) delineation guideline, clinical (CTV) used treatment planning...
Abstract Background Diffuse gliomas display heterogeneous biology, natural history, response to treatments, and outcome. According the 2021 WHO Classification, an integration of histological molecular factors is needed for diagnosis diffuse gliomas. The Italian Association Neuro-Oncology (AINO), with participation Society Neurosurgery (SINch), promoted a survey explore how diagnostic criteria are integrated into clinical practice in national framework. Material Methods A web-based containing...