Irene Zammarchi

ORCID: 0000-0002-3121-0639
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Colorectal Cancer Screening and Detection
  • Microscopic Colitis
  • Radiomics and Machine Learning in Medical Imaging
  • Gut microbiota and health
  • Eosinophilic Esophagitis
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Adrenal Hormones and Disorders
  • Celiac Disease Research and Management
  • Mycobacterium research and diagnosis
  • Diabetes and associated disorders
  • Barrier Structure and Function Studies
  • Diverticular Disease and Complications
  • Congenital gastrointestinal and neural anomalies
  • Digestive system and related health
  • Whipple's Disease and Interleukins
  • Ultrasound in Clinical Applications
  • AI in cancer detection
  • Nuclear Physics and Applications
  • Abdominal Surgery and Complications
  • Phonocardiography and Auscultation Techniques
  • Liver Diseases and Immunity
  • Pancreatic and Hepatic Oncology Research
  • Photoacoustic and Ultrasonic Imaging
  • Intraperitoneal and Appendiceal Malignancies

APC Microbiome Institute
2023-2025

University College Cork
2023-2025

University of Brescia
2020-2025

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2023-2024

Brescia University
2023

University of Pavia
2023

A lifelong gluten-free diet (GFD) is the only treatment for celiac disease and other gluten-related disorders. Nevertheless, strict adherence to GFD often challenging due concerns about social isolation, risk of gluten contaminations, high cost, poor quality taste products. Moreover, although effective in achieving mucosal healing, it may lead dietary imbalances nutrient deficiencies over a long period time. To overcome these issues, several wheat flours have been developed create products...

10.3390/nu16071006 article EN Nutrients 2024-03-29

Absence of neutrophils is the minimum standard to consider histological remission ulcerative colitis [UC]. The PICaSSO Histological Remission Index [PHRI] a new simple index for UC, based only on detection neutrophils. We evaluate PHRI's correlation with endoscopy and its prognostic value compared other established indices.

10.1093/ecco-jcc/jjad110 article EN cc-by Journal of Crohn s and Colitis 2023-06-29

Patients with inflammatory bowel disease (IBD) in clinical and endoscopic remission may still experience relapse. Therefore, there is a need to identify outcome predictors. Recently, the role of neutrophils predicting outcomes ulcerative colitis (UC) has been highlighted. Furthermore, impairment intestinal barrier plays key forecasting IBD.

10.1002/ueg2.12677 article EN cc-by-nc-nd United European Gastroenterology Journal 2024-10-03

Abstract Background Incidence of ulcerative colitis (UC) in elderly population is increasing because ageing and its minimal impact on life span. Data natural history, outcomes therapeutic strategies are limited. Our aim to characterize UC elderly-onset patients followed at our Inflammatory Bowel Disease outpatient clinic compare with adult-onset UC. Methods From January 2000 June 2019, 94 diagnosed after the age 65 years (elderly group, E-O) were identified matched 1–1 according gender...

10.1186/s12876-020-01296-x article EN cc-by BMC Gastroenterology 2020-05-12

To characterize patients with APS type 4 among those affected by diagnosed and monitored at our local Reference Center for Autoimmune Polyglandular Syndromes.Monocentric observational retrospective study enrolling in a Center. Clinical records were retrieved analyzed.111 subjects (51 males) 4, mean age the onset was 23.1 ± 15.1 years. In 15 diagnosis of performed during first clinical evaluation, other 96 after latency 11 years (range 1-46). The most frequent diseases I diabetes mellitus...

10.3389/fendo.2023.1236878 article EN cc-by Frontiers in Endocrinology 2023-10-23
Marietta Iacucci Stefanos Bonovas Alina Bazarova Rosanna Cannatelli R Ingram and 95 more Nunzia Labarile Olga Maria Nardone Tommaso Lorenzo Parigi Daniele Piovani Keith Siau Samuel C. Smith Irene Zammarchi José G. Ferraz Gionata Fiorino R Kiesslich Remo Panaccione Adolfo Parra‐Blanco Mariabeatrice Principi Gian Eugenio Tontini Toshio Uraoka Subrata Ghosh Abdullah Abbasi Adele Wargen Ahmed Feroz Alessandra Dell’Era Alessandra Piagnani Alessandro Rimondi Alessia Chini Alessia Dalila Guarino Alessia Todeschini Amar Srinivasa Andrea Sorge Angelica Toppeta Anna M Carvalhas Gabrielli Anna Testa Anthony R. MacLean Antonella Contaldo A. M. D. Churchhouse Anderson Matheus Pereira da Silva Beatrice Marinoni Chiara Lillo Christopher N. Andrews Ciro Lentano Costantino Sgamato Daniele Gridavilla Daniele Noviello Danny Cheung Dhanai Di Paolo D. Novielli Dominic King Edoardo Borsotti Eleanor Liu Elena Arsiè Elisa Farina Elisabetta Filippi E. Annoscia Fabiana Castiglione Fenella Marley Francesca Ferretti Francesco Conforti Francis Egbuonu Fulvio Salvatore D’Abramo Giulia Scardino Giuseppe Indellicati Giuseppe Losurdo Antonietta Gerarda Gravina Ian Beales Ibrahim Al Bakir Ilaria Ditonno Imma Di Luna Imran Tahir Irene Bergns Irene Brescia Isabel Carbery Ismaeel Al-Talib Jawad Azhar Jeffrey Butterworth Joel James Joëlle St‐Pierre John R. Jacob Jordan Iannuzzi Kathleen Todd Kelly Chatten Leah Gilroy Lekshmy S. Pillai Luca Pastorelli Lucienne Pellegrini Lushen Pillay Marco Romano Maria Camilla Monico Mariapaola Piazzolla Marius Paraoan Marta Patturelli Martino Mezzapesa Matthew Woo Maxime Delisle Melissa Chan Michael A. Gómez Zoe Michael Milli Gupta

Inflammatory bowel disease (IBD) increases risk of dysplasia and colorectal cancer. Advanced endoscopic techniques allow for the detection characterization IBD dysplastic lesions, but specialized training is not widely available. We aimed to develop validate an online platform improve colonic lesions in IBD: OPtical diagnosis Training Improve Characterization Bowel Disease (OPTIC-IBD).

10.1016/j.gie.2023.11.018 article EN cc-by-nc-nd Gastrointestinal Endoscopy 2023-11-21

Abstract Background In Italy, the incidence of SARS-CoV-2 infection peaked in April and November 2020, defining two pandemic waves coronavirus disease 2019 (COVID-19). This study compared characteristics outcomes patients with inflammatory bowel (IBD) infections between waves. Methods Observational longitudinal IBD infection. Patients established diagnoses were consecutively enrolled periods: (i) first wave, from 1 March 2020 to 31 May 2020; (ii) second 15 September December 2020. Results We...

10.1186/s12876-023-02841-0 article EN cc-by BMC Gastroenterology 2023-07-05

Aims Virtual Chromoendoscopy (VCE) has proven effective in predicting disease activity Ulcerative Colitis (UC), although challenges persist regarding local availability and expertise. Artificial intelligence (AI) models applied to VCE have demonstrated a remarkable ability rapidly, objectively, accurately predict inflammation. Nonetheless, training machine algorithms across different enhancement modalities remains challenging. Hence, this study pioneers novel model designed simultaneously...

10.1055/s-0044-1782901 article EN Endoscopy 2024-04-01

Aims PSC colitis is associated with an increased risk of colorectal carcinoma. Endoscopic monitoring crucial since endoscopic and histological activity can persist in even during clinical remission. Recent evidence suggests that the presence barrier dysfunction may predict relapse quiescent patients. This study aims to assess mucosal healing evaluate potential outcomes by combining ultra-high magnification endocytoscope (ECS) intestinal protein markers.

10.1055/s-0044-1783014 article EN Endoscopy 2024-04-01
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