A5045898757- Cancer, Hypoxia, and Metabolism
- Glioma Diagnosis and Treatment
- Mitochondrial Function and Pathology
- Regional Development and Environment
- Adipose Tissue and Metabolism
- Monetary Policy and Economic Impact
- Retinal Diseases and Treatments
- Nanomaterials for catalytic reactions
- Urban Design and Spatial Analysis
- Ammonia Synthesis and Nitrogen Reduction
- Global trade and economics
- Retinal Development and Disorders
- Peroxisome Proliferator-Activated Receptors
- Vascular Malformations and Hemangiomas
- Energy, Environment, Economic Growth
- Catalytic Cross-Coupling Reactions
- Economics of Agriculture and Food Markets
- Urban Transport and Accessibility
- Esophageal and GI Pathology
- Metal-Organic Frameworks: Synthesis and Applications
- Foreign Body Medical Cases
- Water Resources and Management
- Covalent Organic Framework Applications
- Calcium signaling and nucleotide metabolism
- RNA Interference and Gene Delivery
Nanjing Medical University
2014-2025
Wannan Medical College
2025
Jiangsu Province Hospital
2020-2024
Ningbo University Affiliated Hospital
2023
Zhengzhou University
2020-2023
Second Affiliated Hospital of Nanjing Medical University
2023
Jiangsu Cancer Hospital
2023
Zhengzhou Children's Hospital
2023
Beijing Institute of Technology
2017-2022
Nanjing University
2022
Radiotherapy is a major component of standard-of-care treatment for gliomas, the most prevalent type brain tumor. However, resistance to radiotherapy remains concern. Identification mechanisms governing radioresistance in gliomas could reveal improved therapeutic strategies treating patients. Here, we report that mitochondrial metabolic pathways are suppressed radioresistant through integrated analyses transcriptomic data from glioma specimens and cell lines. Decreased expression peroxisome...
The tunability of reaction pathways is required for exploring efficient and low cost catalysts ammonia synthesis. There an obstacle by the limitations arising from scaling relation this purpose. Here, we demonstrate that alkali earth imides (AeNH) combined with transition metal (TM = Fe, Co Ni) can overcome difficulty utilizing functionalities concerted role active defects on support surface loaded metals. These enable production through multiple pathways. rate Co/SrNH as high 1686.7...
As a global phenomenon, the gating form of gated community is often understood within general context which by and large ignores significance unique historical, political socio-cultural momentums in specific urban context. Through historical review vicissitudes cities, neighbourhoods residential compounds China their physical evolution as well social change behind them, this paper endeavours to reveal that enclosed forms organizational patterns are deeply ingrained Chinese history city...
Abstract Researchers commonly use cyclization recombination enzyme/locus of X-over P1 (Cre/loxP) technology-based conditional gene knockouts model mice to investigate the functional roles genes interest in Sertoli and Leydig cells within testis. However, shortcomings these genetic tools include high costs, lengthy experimental periods, limited accessibility for researchers. Therefore, exploring alternative silencing techniques is great practical value. In this study, we employed...
This study aims to examine the association between single nucleotide gene polymorphisms (SNPs) of GAB1, GAB2, and GAB3 genetic susceptibility essential hypertension in Chinese Han population. The findings this research will contribute understanding underlying causes hypertension. A community-based sampling survey was conducted two towns south Jiangsu Province investigate correlation included a total 2119 cases 2317 healthy controls, with an average follow-up period 10.75 years. genotypes...
MSX1 is a favorable candidate gene for susceptibility to non-syndromic orofacial clefts (NSOCs). However, the roles of genetic variants in development NSOC are controversial and vary among human populations. In present study, 4 potentially functional single-nucleotide polymorphisms (SNPs) (rs12532 3′-untranslated region [UTR], rs3821947, rs3821949, rs4464513 5′ upstream) were investigated case-control study 602 cases 605 healthy controls. The findings showed that rs12532 located within...
This study investigates the effect of environmental regulation on green total factor productivity (GTFP) marine economy in China.Environmental can reduce pollution, and it is key to sustainable development, but we scarcely know its effects economy.Although increases cost economic operation reduces profits, also improve through stimulating more innovation activities.Therefore, net depends relative size two competitive effects.We present following evidence basis China's coastal provinces.(1)...
A multistep electron transfer process is realized over C12A7:e − electride composite material. The graphene promotes from through surface Pd to the aryl halide substrates, affording a series of cross-coupling reactions.
The recent proliferation of alluring, consumerism-based Central Pedestrian Districts (CPDs) in large Chinese cities raises the question as to how far these newly redeveloped environments can truly contribute supply diverse public use. Based upon recognition that nature space is fluid and constantly evolving, this paper reviews historical evolution physical form social function Nanjing Road Shanghai, one biggest CPDs China, argues that, contrast with its past, currently offering more uses...
Abstract Transition metal catalysis has played an important role in modern organic chemistry. In order to develop highly efficient and sustainable methodologies, considerable efforts have been devoted combining the benefits of homogeneous heterogeneous catalysis. Porous cages (POCs) are a relatively new type discrete molecules with permanent cavities good solubilities. These intrinsic properties make POCs expedient catalyst support for homogenization transition nanoparticles (MNPs). This...
Abstract Choroidal neovascularization (CNV) occurs in neovascular age-related macular degeneration (AMD) and often leads to permanent visual impairment. Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is the gold standard for treatment CNV. However, anti-VEGF did not always cause vision improvement sometimes had detrimental effects on normal retinal tissues. Herein, we identified a novel retinoic acid drug, EYE-502, which great therapeutic Administration...
Abstract Traditional villages, as an important bearer of traditional culture, are the foundation for survival and reproduction but with impact rapid urbanization development information, cultural protection inheritance villages facing a huge impact. This paper takes Dayu Bay research object, from point perspective genes, systematically sorts out elements Bay, constructs genealogy Bay's classifies analyzes its material immaterial problems exposed in by sorting builds system village genes...
Introduction 11β-Hydroxylase deficiency (11β-OHD, OMIM#202010) is the second most common form of congenital adrenal hyperplasia (CAH) caused by pathogenic variants in CYP11B1 gene. Both single nucleotide variations (SNV)/small insertion and deletion genomic rearrangements are important causes 11β-OHD. Among these variant types, CYP11B2 / chimeras only contribute to a minority cases. Heterozygote cases (chimera combined with SNV) very rare, genetic analysis can be challenging. Case...
In recent decades the Yinma River Basin has been receiving increasing pollution from industrial and domestic wastewater, agriculture, livestock production -which are all potential 4-NP sources.Thus, this work investigated spatial-seasonal distribution, risks, seasonal variations of 4-nonylphenol in aquatic environment Basin.The results indicated that highest concentrations water sediment occurred livestock-production, industrial, domestic-wastewater areas, lowest agricultural areas; a...
Abstract Sulfonyl chloride has been rarely used as Cl source in transition metal‐catalyzed C−H functionalizations. We report the unprecedented copper‐catalyzed remote C5‐chlorination of substituted 8‐amidoquinolines with sulfonyl under 1 atm oxygen. 10 chlorides and 15 were tested, generating moderate to high yields. The catalytic system showed regio‐selectivity, well good functional group tolerance.
Complete congenital achromatopsia is a devastating hereditary visual disorder. Mutations in the CNGB3 gene account for more than 50% of all known cases achromatopsia. This work investigated efficiency subretinal (SR) delivered AAV8 (Y447, 733F) vector containing human PR2.1 promoter and cDNA Cngb3-/-/ Nrl-/- mice. The mouse was cone-dominant model with Cngb3 channel deficiency, which partially mimicked all-cone foveal structure mutations. Following SR delivery vector, AAV-mediated expression...
HomePlant DiseaseVol. 106, No. 3First Report of Pantoea dispersa Causing Brown Blotch Disease in Flammulina filiformis China PreviousNext DISEASE NOTE OPENOpen Access licenseFirst ChinaHaijing Hu, Miao Xu, Haiyan Song, Zhijun Zhai, Minghui Chen, Jianping Zhou, Dianming and Yang GaoHaijing HuBioengineering Technological Research Centre for Edible Medicinal Fungi, Jiangxi Agricultural University, Nanchang, 330045, P.R. China, XuBioengineering SongKey Laboratory Crop Physiology, Ecology Genetic...