- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Advanced Steganography and Watermarking Techniques
- Digital Media Forensic Detection
- Chaos-based Image/Signal Encryption
- Spectroscopy Techniques in Biomedical and Chemical Research
- Medical Imaging Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Image Processing Techniques
- Nanoplatforms for cancer theranostics
- Image Enhancement Techniques
- Advanced Fluorescence Microscopy Techniques
- Human Pose and Action Recognition
- Photodynamic Therapy Research Studies
- Advanced Neural Network Applications
- Face and Expression Recognition
- Medical Image Segmentation Techniques
- Video Surveillance and Tracking Methods
- Advanced Radiotherapy Techniques
- Laser-Ablation Synthesis of Nanoparticles
- Cancer-related molecular mechanisms research
- Optical Coherence Tomography Applications
- Advanced Optical Sensing Technologies
- Nonlinear Optical Materials Studies
- Diabetic Foot Ulcer Assessment and Management
Hunan Normal University
2021-2025
Polytechnic University of Timişoara
2019
ETH Zurich
2019
Xidian University
2009-2018
MEI Technologies (United States)
2018
Korea University
2013-2015
Air Force Medical University
2012-2013
Xijing Hospital
2012-2013
Institute of Automation
2012-2013
Chinese Academy of Sciences
2012-2013
Existing enhancement methods are empirically expected to help the high-level end computer vision task: however, that is observed not always be case in practice. We focus on object or face detection poor visibility enhancements caused by bad weathers (haze, rain) and low light conditions. To provide a more thorough examination fair comparison, we introduce three benchmark sets collected real-world hazy, rainy, low-light conditions, respectively, with annotated objects/faces. launched UG <sup...
Among various digital image formats used in daily life, the Joint Photographic Experts Group (JPEG) is most popular. Therefore, reversible data hiding (RDH) JPEG images important and useful for many applications such as archive management authentication. However, RDH considerably more difficult than that uncompressed because there less information redundancy images, any modification compressed domain may introduce distortion host image. Furthermore, along with embedding capacity fidelity...
As the most accurate model for simulating light propagation in heterogeneous tissues, Monte Carlo (MC) method has been widely used field of optical molecular imaging. However, MC is time-consuming due to calculations a large number photons tissues. The structural complexity tissues further increases computational time. In this paper we present parallel implementation simulation whose surfaces are constructed by different triangle meshes. On basis graphics processing units (GPU), code...
This paper reviews the first challenge on image dehazing (restoration of rich details in hazy image) with focus proposed solutions and results. The had 2 tracks. Track 1 employed indoor images (using I-HAZE dataset), while outdoor O-HAZE dataset). have been captured presence real haze, generated by professional haze machines. dataset contains 35 scenes that correspond to domestic environments, objects different colors specularities. 45 depicting same visual content recorded haze-free...
Fluorescent gold nanoclusters (AuNCs) have been extensively studied due to their unique construction and distinctive properties, which place them between single metal atoms larger nanoparticles. The dimension of AuNCs is comparable the Fermi wavelength electrons, lead size‐dependent fluorescence other molecule‐like properties. In this review, we summarize various synthesis strategies fluorescent recent advances biological applications such as biosensing, biolabeling, bioimaging. synthetic...
Optical molecular imaging resulting from Cerenkov radiation has become a motivating topic recently and will potentially open new avenues for the study of small animal imaging. Cerenkov-based optical taken living animals in vivo been studied with two-dimensional (2D) planar geometry three-dimensional (3D) homogeneous mouse model. In this study, we performed 3D luminescence tomography (CLT) using heterogeneous model an implanted Na(131)I radioactive source, which provided accurate location...
Reversible data hiding hides in an image such that the original is recoverable. This paper presents a novel embedding framework with reduced distortion called skewed histogram shifting using pair of extreme predictions. Unlike traditional prediction error schemes, where only one good used to generate histogram, proposed scheme uses predictions two histograms. By exploiting structure pixels from peak and short tail are for embedding, which decreases lesser number being shifted. Detailed...
In this paper, we present an incomplete variables truncated conjugate gradient (IVTCG) method for bioluminescence tomography (BLT). Considering the sparse characteristic of light source and insufficient surface measurement in BLT scenarios, combine a sparseness-inducing (ℓ1 norm) regularization term with quadratic error IVTCG-based framework solving inverse problem. By limiting number updated at each iterative combining variable splitting strategy to find search direction more efficiently,...
In this paper, we present a novel Distribution-Aware Single-stage (DAS) model for tackling the challenging multi-person 3D pose estimation problem. Different from existing top-down and bottom-up methods, proposed DAS simultaneously localizes person positions their corresponding body joints in camera space one-pass manner. This leads to simplified pipeline with enhanced efficiency. addition, learns true distribution of regression positions, rather than making simple Laplacian or Gaussian...
The study of light propagation in turbid media has attracted extensive attention the field biomedical optical molecular imaging. In this paper, we present a software platform for simulation named "Molecular Optical Simulation Environment (MOSE)". Based on gold standard Monte Carlo method, MOSE simulates both tissues with complicated structures and through free-space. particular, synthesizes realistic data bioluminescence tomography (BLT), fluorescence (FMT), diffuse (DOT). user-friendly...
Recent advances have recognized metabolic reprogramming as an underlying mechanism for cancer drug resistance. However, the role of cholesterol metabolism in resistance remain elusive. Herein, we report increased accumulation cholesteryl ester gemcitabine-resistant pancreatic ductal adenocarcinoma (PDAC) cells. A potent inhibitor acyl-CoA acyltransferase-1 (ACAT-1), avasimibe, effectively suppressed proliferation PDAC Combination avasimibe and gemcitabine showed strong synergistic effect...
Reversible data hiding with automatic contrast enhancement methods provide an interoperable way to reduce the storage requirement for image applications: original can be recovered from enhanced without any additional information. Unlike previous work, where goal was maximize contrast, proposed method increases appropriate level using idea called brightness preservation. This is achieved by adaptive bin selection process based on brightness. Extensive experimental results verify that images...
This paper reviews the first NTIRE challenge on perceptual image enhancement with focus proposed solutions and results. The participating teams were solving a real-world photo problem, where goal was to map low-quality photos from iPhone 3GS device same captured Canon 70D DSLR camera. considered problem embraced number of computer vision subtasks, such as denoising, resolution sharpness enhancement, color/contrast/exposure adjustment, etc. target metric used in this combined PSNR SSIM scores...
This paper reviews the first NTIRE challenge on quality enhancement of compressed video, with a focus proposed methods and results.In this challenge, new Large-scale Diverse Video (LDV) dataset is employed.The has three tracks.Tracks 1 2 aim at enhancing videos by HEVC fixed QP, while Track 3 designed for x265 bit-rate.Besides, Tracks targets improving fidelity (PSNR), perceptual quality.The tracks totally attract 482 registrations.In test phase, 12 teams, 8 teams 11 submitted final results...
Background Both obesity (OB) and periodontitis (PD) are chronic non-communicable diseases, numerous epidemiological studies have demonstrated the association between these two diseases. However, molecular mechanisms that could explain OB PD largely unclear. This study aims to investigate common gene signatures biological pathways in through bioinformatics analysis of publicly available transcriptome datasets. Methods The RNA expression profile datasets (GSE104815) (GSE106090) were used as...
Light-absorbing nanoparticles that are heated by short laser pulses can transiently increase membrane permeability. We evaluate the permeability flow cytometry assaying of propidium iodide and fluorescein isothiocyanate dextran (FITC-D) using different sources. The dependence transfection efficiency on parameters such as pulse duration, irradiant exposure, irradiation mode is investigated. For nano- also picosecond irradiation, we show a parameter range where reliable permeabilization...
Bioluminescence tomography (BLT) is a new optical molecular imaging modality, which can monitor both physiological and pathological processes by using bioluminescent light-emitting probes in small living animal. Especially, this technology possesses great potential drug development, early detection, therapy monitoring preclinical settings. In the present study, we developed dual modality BLT prototype system with Micro-computed (MicroCT) registration approach, improved quantitative...
Optical tomography can demonstrate accurate three-dimensional (3D) imaging that recovers the 3D spatial distribution and concentration of luminescent probes in biological tissues, compared with planar imaging. However, tomographic approach is extremely difficult to implement due complexity reconstruction surface flux from multi-view two dimensional (2D) measurements on subject surface. To handle this problem, a novel effective method proposed paper determine 2D photographic images acquired...
Background Cerenkov luminescence tomography (CLT) provides the three-dimensional (3D) radiopharmaceutical biodistribution in small living animals, which is vital to biomedical imaging. However, existing single-spectral and multispectral methods are not very efficient effective at reconstructing distribution of radionuclide tracer. In this paper, we present a semi-quantitative radiation spectral characteristic-based source reconstruction method named hybrid CLT, efficiently reconstruct tracer...
This paper reviews the second NTIRE challenge on image dehazing (restoration of rich details in hazy image) with focus proposed solutions and results. The training data consists from 55 images (with dense haze generated an indoor or outdoor environment) their corresponding ground truth (haze-free) same scene. has been produced using a professional haze/fog generator that imitates real conditions scenes. evaluation comparison dehazed images. process was learnable through provided pairs...
Automatic image enhancement is increasingly becoming a popular tool for the smartphone environment. The automatically enhances right after it has been stored to enhance user's experience. But, because enhancements are subjective and dependent on image, original backed up provide recovery option. This requirement inevitably increases storage requirement. In order reduce it, novel automatic contrast based reversible data hiding (ACERDH) proposed. proposed method mimics equalization effect...
As a novel modality of molecular imaging, bioluminescence tomography (BLT) is used to in vivo observe and measure the biological process at cellular level small animals. The core issue BLT determine distribution internal bioluminescent sources from optical measurements on external surface. In this paper, new algorithm presented for source reconstruction based adaptive hp-finite element method. Using mesh refinement strategy intelligent permissible region, we can obtain more accurate...
Cerenkov luminescence tomography (CLT) has become a valuable tool for preclinical imaging because of its ability reconstructing the three-dimensional distribution and activity radiopharmaceuticals. However, it is still far from mature technology suffers relatively low spatial resolution due to ill-posed inverse problem tomographic reconstruction. In this paper, we presented single photon emission computed (SPECT)-guided reconstruction method CLT, in which priori information permissible...
Purpose: Due to the efficient bioconjugation and highly photothermal effect, gold nanoparticles can stain receptor-overexpressing cancer cells through specific targeting of ligands receptors, strongly absorb light efficiently convert it into heat based on property surface plasmon resonance, then induce localized protein denaturation cell death. Methods: Two nanoparticle–antibody conjugates, gold-BerH2 antibody (anti-CD30 receptor) gold-ACT1 (anti-CD25-receptor), were synthesized. Gold-BerH2...